The everolimus eluting Synergy Megatron

bifurcation drug-eluting stent left main

Journal

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
ISSN: 1522-726X
Titre abrégé: Catheter Cardiovasc Interv
Pays: United States
ID NLM: 100884139

Informations de publication

Date de publication:
Dec 2023
Historique:
revised: 03 10 2023
received: 12 07 2023
accepted: 22 10 2023
pubmed: 10 11 2023
medline: 10 11 2023
entrez: 10 11 2023
Statut: ppublish

Résumé

The Synergy Megatron To report the short- to medium-term clinical outcomes from the European Synergy Megatron This registry was an investigator-initiated study conducted at 14 European centers. The primary outcome was target lesion failure (TLF), defined as the composite of cardiovascular death, target vessel myocardial infarction (MI), and target lesion revascularisation. Five hundred seventy-five patients underwent PCI with Megatron Use of the Synergy Megatron

Sections du résumé

BACKGROUND BACKGROUND
The Synergy Megatron
AIMS OBJECTIVE
To report the short- to medium-term clinical outcomes from the European Synergy Megatron
METHODS METHODS
This registry was an investigator-initiated study conducted at 14 European centers. The primary outcome was target lesion failure (TLF), defined as the composite of cardiovascular death, target vessel myocardial infarction (MI), and target lesion revascularisation.
RESULTS RESULTS
Five hundred seventy-five patients underwent PCI with Megatron
CONCLUSIONS CONCLUSIONS
Use of the Synergy Megatron

Identifiants

pubmed: 37948428
doi: 10.1002/ccd.30902
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1222-1228

Subventions

Organisme : British Heart Foundation
Pays : United Kingdom

Informations de copyright

© 2023 The Authors. Catheterization and Cardiovascular Interventions published by Wiley Periodicals LLC.

Références

Mohammad MA, Persson J, Buccheri S, et al. Trends in clinical practice and outcomes after percutaneous coronary intervention of unprotected left main coronary artery. J Am Heart Assoc. 2022;11:24040.
Vora AN, Dai D, Gurm H, et al. Temporal trends in the risk profile of patients undergoing outpatient percutaneous coronary intervention: a report from the National Cardiovascular Data Registry's CathPCI Registry. Circul Cardiovasc Interv. 2016;9(3):e003070.
Jaffe R, Halon DA, Shiran A, Rubinshtein R. Percutaneous treatment of aorto-ostial coronary lesions: current challenges and future directions. Int J Cardiol. 2015;186:61-66.
Tsunoda T, Nakamura M, Wada M, et al. Chronic stent recoil plays an important role in restenosis of the right coronary ostium. Coron Artery Dis. 2004;15:39-44.
Hsieh IC, Chen CC, Chang SH, et al. Acute and long-term outcomes of drug-eluting stent implantations in aorto-ostial, left anterior descending artery-ostial, and nonostial lesions. Catheter Cardiovasc Interv. 2013;82:727-734.
Musallam A, Chezar-Azerrad C, Torguson R, et al. Procedural outcomes of patients undergoing percutaneous coronary intervention for De Novo lesions in the ostial and proximal left circumflex coronary artery. Am J Cardiol. 2020;135:62-67.
Hyun J, Kim JH, Jeong Y, et al. Long-term outcomes after PCI or CABG for left main coronary artery disease according to lesion location. JACC: Cardiovasc Interv. 2020;13:2825-2836.
Boston Scientific. SYNERGY MEGATRONTM Stent System n.d. Accessed November 17, 2022. https://www.bostonscientific.com/en-EU/products/stents-coronary/synergy-stent-system/megatron.html
Samant S, Wu W, Zhao S, et al. Computational and experimental mechanical performance of a new everolimus-eluting stent purpose-built for left main interventions. Sci Rep. 2021;11:8728.
Mailey JA, Ahmed M, Hogg M, et al. Initial experiences of percutaneous coronary intervention using a new-generation Everolimus-Eluting Stent platform. J Invasive Cardiol. 2021;33:784.
Chatzizisis YS, Makadia J, Zhao S, et al. First-in-human computational preprocedural planning of left main interventions using a new Everolimus-Eluting Stent. JACC: Case Reports. 2022;4:325-335.
Neumann F-J, Sousa-Uva M, Ahlsson A, et al. 2018 ESC/EACTS guidelines on myocardial revascularization. Eur Heart J. 2018;40:87-165.
Garcia-Garcia HM, McFadden EP, Farb A, et al. Standardized end point definitions for coronary intervention trials: the academic research consortium-2 consensus document. Circulation. 2018;137:2635-2650.
Doll JA, O'Donnell CI, Plomondon ME, Waldo SW. Contemporary clinical and coronary anatomic risk model for 30-day mortality after percutaneous coronary intervention. Circul Cardiovasc Interv. 2021;14:E010863.
McAllister KSL, Ludman PF, Hulme W, et al. A contemporary risk model for predicting 30-day mortality following percutaneous coronary intervention in England and Wales. Int J Cardiol. 2016;210:125-132.
Peterson ED, Dai D, DeLong ER, et al. Contemporary mortality risk prediction for percutaneous coronary intervention. JACC. 2010;55:1923-1932.
Rubinshtein R, Ben-Dov N, Halon DA, Lavi I, Finkelstein A, Lewis BS. Geographic miss with aorto-ostial coronary stent implantation: insights from high-resolution coronary computed tomography angiography. EuroIntervention. 2015;11:301-307.
Yamamoto K, Sato T, Salem H, et al. Mechanisms and treatment outcomes of ostial right coronary artery in-stent restenosis. EuroIntervention. 2023;19(5):e383-e393. doi:10.4244/eij-d-23-00107
Rhee TM, Park KW, Lee JM, et al. Predictors and long-term clinical outcome of longitudinal stent deformation: insights from pooled analysis of Korean multicenter drug-eluting stent cohort. Circul Cardiovasc Interv. 2017;10:e005518.
Kim S-Y, Maehara A, Merkely B, et al. TCT-44 frequency and impact of acute stent deformation after PCI of left main coronary artery disease: an EXCEL trial intravascular ultrasound substudy. JACC. 2017;70:B19.
Gil RJ, Bil J, Kern A, et al. Angiographic restenosis in coronary bifurcations treatment with regular drug eluting stents and dedicated bifurcation drug-eluting BiOSS stents: analysis based on randomized POLBOS i and POLBOS II studies. Cardiovasc Ther. 2020;2020:1-8.
Toth GT, Achim A, Kafka M, et al. Bench test and in vivo evaluation of longitudinal stent deformation during proximal optimisation. EuroIntervention. 2022;18:83-90.
Stone GW, Sabik JF, Serruys PW, et al. Everolimus-Eluting stents or bypass surgery for left main coronary artery disease. N Engl J Med. 2016;375:2223-2235.
Mäkikallio T, Holm NR, Lindsay M, et al. Percutaneous coronary angioplasty versus coronary artery bypass grafting in treatment of unprotected left main stenosis (NOBLE): a prospective, randomised, open-label, non-inferiority trial. The Lancet. 2016;388:2743-2752.
Hildick-Smith D, Egred M, Banning A, et al. The European bifurcation club left main coronary stent study: a randomized comparison of stepwise provisional vs. systematic dual stenting strategies (EBC MAIN). Eur Heart J. 2021;42:3829-3839.
Fath-Ordoubadi F, Spaepen E, El-Omar M, et al. Outcomes in patients with acute and stable coronary syndromes; insights from the prospective NOBORI-2 study. PLoS One. 2014;9:e88577.
Chung SC, Gedeborg R, Nicholas O, et al. Acute myocardial infarction: a comparison of short-term survival in national outcome registries in Sweden and the UK. The Lancet. 2014;383:1305-1312.
Chan MY, Sun JL, Newby LK, et al. Long-term mortality of patients undergoing cardiac catheterization for ST-elevation and non-ST-elevation myocardial infarction. Circulation. 2009;119:3110-3117.
Heestermans AACM, van Werkum JW, Zwart B, et al. Acute and subacute stent thrombosis after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: incidence, predictors and clinical outcome. J Thromb Haemostasis. 2010;8:2385-2393.
Han Y, Liu H, Yang Y, et al. A randomised comparison of biodegradable polymer-and permanent polymer-coated platinum-chromium everolimus eluting coronary stents in China: the EVOLVE China study. EuroIntervention. 2017;13:1210-1217.
Ploumen EH, Pinxterhuis TH, Buiten RA, et al. Final 5-year report of the randomized BIO-RESORT trial comparing 3 contemporary drug-eluting stents in all-comers. J Am Heart Assoc. 2022;11:26041.
Kereiakes DJ, Meredith IT, Windecker S, et al. Efficacy and safety of a novel bioabsorbable polymer-coated, everolimus-eluting coronary stent. Circul Cardiovasc Interv. 2015;8:e002372.

Auteurs

Kalpa De Silva (K)

Cardiovascular Division, St Thomas' Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Coronary Research Group, British Heart Foundation Centre of Research Excellence, King's College London, London, UK.

Matthew E Li Kam Wa (ME)

Cardiovascular Division, St Thomas' Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Coronary Research Group, British Heart Foundation Centre of Research Excellence, King's College London, London, UK.

Tim Wells (T)

Cardiology Department, Salisbury District Hospital, Salisbury NHS Foundation Trust, Salisbury, UK.

Abdul Mozid (A)

Cardio Respiratory Clinical Services Unit, Leeds General Infirmary, The Leeds Teaching Hospitals NHS Trust, Leeds, UK.

Andrew Ladwiniec (A)

Department of Cardiology, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, UK.

Brian G Hynes (BG)

Cardiology Department, University Hospital Galway, Galway, Ireland.

Ashish Kotecha (A)

Department of Cardiology, Royal Devon and Exeter Hospital, Royal Devon University Healthcare NHS Foundation Trust, Exeter, UK.

Karim Ratib (K)

Cardiology Department, Royal Stoke University Hospital, University Hospitals of North Midlands NHS Trust, Stoke, UK.

Sinjini Biswas (S)

Bristol Heart Institute, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.

Nicolas Amabile (N)

Cardiology Department, L'Institut Mutualiste Montsouris, Paris, France.

Pierre Deharo (P)

Cardiology Department, Assistance Publique Hôpitaux de Marseille, Marseille, France.

Margaret McEntagart (M)

Cardiology Department, Golden Jubilee Hospital, NHS Golden Jubilee, Glasgow, UK.

James C Spratt (JC)

Cardiology Clinical Academic Group, St George's University Hospital, St George's University Hospitals NHS Foundation Trust, London, UK.

Franck Digne (F)

Cardiology Department, Centre Cardiologique du Nord, Saint Denis, France.

Meadhbh Hogg (M)

Department of Cardiology, Belfast Health and Social Care Trust, Belfast, UK.

Jonathan A Mailey (JA)

Department of Cardiology, Belfast Health and Social Care Trust, Belfast, UK.

Simon J Walsh (SJ)

Department of Cardiology, Belfast Health and Social Care Trust, Belfast, UK.

Sundeep S Kalra (SS)

Cardiology Department, Royal Free Hospital, Royal Free London NHS Foundation Trust, London, UK.

Classifications MeSH