Solid-state NMR spectroscopy for structural studies of polypeptides and lipids in extended physiological membranes.
(1)H-detected ultrafast MAS
Dynamics
Membrane proteins
Solid-state NMR
Structural biology
Supported lipid bilayers
Journal
Biochimica et biophysica acta. Biomembranes
ISSN: 1879-2642
Titre abrégé: Biochim Biophys Acta Biomembr
Pays: Netherlands
ID NLM: 101731713
Informations de publication
Date de publication:
13 May 2023
13 May 2023
Historique:
received:
06
04
2023
revised:
18
04
2023
accepted:
26
04
2023
medline:
11
11
2023
pubmed:
11
11
2023
entrez:
10
11
2023
Statut:
aheadofprint
Résumé
Solid-state NMR is a quickly developing technique that allows one to obtain structural information at atomic resolution in extended lipid bilayers in a rather unique manner. Two approaches have been developed for membrane proteins and peptides namely magic angle sample spinning and the use of uniaxially oriented membrane samples. The state-of-the-art of both approaches will be introduced and the perspectives of solid-state NMR spectroscopy in the context of other structural biology techniques, pressing biomedical questions and membrane biophysics will be discussed.
Identifiants
pubmed: 37949788
pii: S0005-2736(23)00044-5
doi: 10.1016/j.bbamem.2023.184162
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
184162Informations de copyright
Copyright © 2023 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: BB is Executive Editor of BBA Biomembranes.