Endothelial progenitor cells as biomarkers of diabetes-related cardiovascular complications.
Biomarkers
Diabetes mellitus
Diabetic vascular complications
Endothelial progenitor cells
Journal
Stem cell research & therapy
ISSN: 1757-6512
Titre abrégé: Stem Cell Res Ther
Pays: England
ID NLM: 101527581
Informations de publication
Date de publication:
10 Nov 2023
10 Nov 2023
Historique:
received:
19
07
2023
accepted:
13
10
2023
medline:
13
11
2023
pubmed:
11
11
2023
entrez:
11
11
2023
Statut:
epublish
Résumé
Diabetes mellitus (DM) constitutes a chronic metabolic disease characterized by elevated levels of blood glucose which can also lead to the so-called diabetic vascular complications (DVCs), responsible for most of the morbidity, hospitalizations and death registered in these patients. Currently, different approaches to prevent or reduce DM and its DVCs have focused on reducing blood sugar levels, cholesterol management or even changes in lifestyle habits. However, even the strictest glycaemic control strategies are not always sufficient to prevent the development of DVCs, which reflects the need to identify reliable biomarkers capable of predicting further vascular complications in diabetic patients. Endothelial progenitor cells (EPCs), widely known for their potential applications in cell therapy due to their regenerative properties, may be used as differential markers in DVCs, considering that the number and functionality of these cells are affected under the pathological environments related to DM. Besides, drugs commonly used with DM patients may influence the level or behaviour of EPCs as a pleiotropic effect that could finally be decisive in the prognosis of the disease. In the current review, we have analysed the relationship between diabetes and DVCs, focusing on the potential use of EPCs as biomarkers of diabetes progression towards the development of major vascular complications. Moreover, the effects of different drugs on the number and function of EPCs have been also addressed.
Identifiants
pubmed: 37950274
doi: 10.1186/s13287-023-03537-8
pii: 10.1186/s13287-023-03537-8
pmc: PMC10636846
doi:
Substances chimiques
Blood Glucose
0
Biomarkers
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
324Subventions
Organisme : Instituto de Salud Carlos III
ID : PI20-00716
Organisme : Consejería de Salud y Consumo, Junta de Andalucía
ID : PI20-00932
Informations de copyright
© 2023. The Author(s).
Références
J Am Coll Cardiol. 2005 May 3;45(9):1449-57
pubmed: 15862417
N Engl J Med. 2001 May 24;344(21):1608-21
pubmed: 11372014
Biomedicines. 2021 Sep 03;9(9):
pubmed: 34572333
Am J Pathol. 2010 Jan;176(1):504-15
pubmed: 19948824
PLoS One. 2012;7(11):e48283
pubmed: 23139771
Diabetes Care. 2006 Mar;29(3):714-6
pubmed: 16505536
Mol Med Rep. 2017 Dec;16(6):8691-8698
pubmed: 28990070
Int J Angiol. 2021 Apr 20;30(4):257-261
pubmed: 34853572
Arch Med Sci. 2012 Nov 9;8(5):899-906
pubmed: 23185202
J Mol Cell Cardiol. 2022 Feb;163:133-146
pubmed: 34743936
Diabetes Care. 2004 May;27(5):1047-53
pubmed: 15111519
J Diabetes Complications. 2020 Apr;34(4):107517
pubmed: 31928893
JAMA Neurol. 2014 Sep;71(9):1143-9
pubmed: 25048157
Cytometry A. 2012 Oct;81(10):856-64
pubmed: 22930579
J Diabetes Investig. 2021 Nov;12(11):1934-1941
pubmed: 34132491
Arterioscler Thromb Vasc Biol. 2014 Jun;34(6):1136-43
pubmed: 24743430
Endocrine. 2015 Feb;48(1):342-5
pubmed: 24802059
Pediatr Res. 2018 Jan;83(1-2):283-290
pubmed: 28915234
Exp Eye Res. 2010 Aug;91(2):229-37
pubmed: 20493838
Acta Histochem. 2022 Jan;124(1):151833
pubmed: 34929523
Endocrine. 2010 Oct;38(2):266-75
pubmed: 20972736
Stem Cells Transl Med. 2022 May 27;11(5):451-460
pubmed: 35365823
Diabetes. 2007 Mar;56(3):666-74
pubmed: 17327434
Diabet Med. 2009 Feb;26(2):171-3
pubmed: 19236621
Diabetologia. 2012 Sep;55(9):2501-12
pubmed: 22648662
Diabetes Metab Syndr Obes. 2020 Oct 09;13:3611-3616
pubmed: 33116712
Diabetes Obes Metab. 2021 Jun;23(6):1409-1414
pubmed: 33565691
Stem Cells Int. 2018 Nov 18;2018:9847015
pubmed: 30581475
Biochim Biophys Acta Gen Subj. 2022 Oct;1866(10):130188
pubmed: 35691459
Am J Cardiol. 1985 Dec 6;56(16):97H-100H
pubmed: 2866709
Nephrol Dial Transplant. 2017 Mar 1;32(3):556-564
pubmed: 28339557
Int J Mol Sci. 2020 Jul 24;21(15):
pubmed: 32722151
N Engl J Med. 2000 Apr 6;342(14):1040-2
pubmed: 10749967
Oxid Med Cell Longev. 2017;2017:7809581
pubmed: 28373902
Ophthalmology. 2018 Oct;125(10):1608-1622
pubmed: 29776671
Diabetes Metab J. 2022 Jan;46(1):15-37
pubmed: 34965646
PLoS One. 2022 May 19;17(5):e0267433
pubmed: 35587929
J Diabetes Res. 2017;2017:1478294
pubmed: 29279853
JAMA Neurol. 2015 Dec;72(12):1510-8
pubmed: 26437251
Diabetes Care. 2005 May;28(5):1163-8
pubmed: 15855583
Front Endocrinol (Lausanne). 2013 Mar 27;4:37
pubmed: 23542897
J Diabetes Investig. 2018 Sep;9(5):998-1015
pubmed: 29499103
Nutrients. 2021 Sep 24;13(10):
pubmed: 34684345
Circ Res. 2012 Feb 17;110(4):624-37
pubmed: 22343557
PeerJ. 2019 Oct 17;7:e7815
pubmed: 31637120
Diabetes Care. 2010 Jul;33(7):1607-9
pubmed: 20357375
Diabetes Res Clin Pract. 2019 Nov;157:107840
pubmed: 31733978
J Clin Endocrinol Metab. 2022 Aug 18;107(9):e3910-e3918
pubmed: 35583559
Endocrine. 2016 May;52(2):244-52
pubmed: 26184417
Eur J Pharmacol. 2011 Jun 1;659(2-3):296-301
pubmed: 21453695
Diabetes. 2007 Jun;56(6):1559-68
pubmed: 17389326
Nat Rev Dis Primers. 2019 Jun 13;5(1):41
pubmed: 31197153
Invest Ophthalmol Vis Sci. 2009 Jan;50(1):392-8
pubmed: 18719083
In Vivo. 2019 Jul-Aug;33(4):1039-1049
pubmed: 31280191
Cardiovasc Diabetol. 2022 Oct 3;21(1):200
pubmed: 36199064
Stem Cells Int. 2022 May 16;2022:4460041
pubmed: 35615696
Nat Rev Dis Primers. 2015 Jul 23;1:15019
pubmed: 27189025
Diabetologia. 2017 Sep;60(9):1668-1677
pubmed: 28597075
J Clin Endocrinol Metab. 2016 Nov;101(11):4205-4213
pubmed: 27583476
Arterioscler Thromb Vasc Biol. 2008 Sep;28(9):1584-95
pubmed: 18669889
Arterioscler Thromb Vasc Biol. 2006 Sep;26(9):2140-6
pubmed: 16857948
Diabetes Res Clin Pract. 2015 Jan;107(1):85-93
pubmed: 25451902
Clinics (Sao Paulo). 2013 May;68(5):665-73
pubmed: 23778412
Cardiovasc Diabetol. 2014 Jul 30;13:110
pubmed: 25074318
Int J Mol Sci. 2018 Jun 20;19(6):
pubmed: 29925789
J Cell Biochem. 2016 Nov;117(11):2443-53
pubmed: 27128219
Int J Mol Sci. 2022 Jul 12;23(14):
pubmed: 35887039
Diabetes. 2004 Jan;53(1):195-9
pubmed: 14693715
J Clin Endocrinol Metab. 2020 Apr 1;105(4):
pubmed: 31589290
Eur Heart J. 2010 Nov;31(21):2625-32
pubmed: 20543191
JACC Cardiovasc Interv. 2017 Aug 28;10(16):1646-1658
pubmed: 28838475
Endothelium. 2008 Sep-Oct;15(5-6):246-53
pubmed: 19065316
Lancet Diabetes Endocrinol. 2015 Feb;3(2):105-13
pubmed: 25466521
Cells. 2022 Dec 28;12(1):
pubmed: 36611906
Diabetes Ther. 2022 Jul;13(7):1327-1337
pubmed: 35676613
World J Diabetes. 2015 Jun 25;6(6):850-67
pubmed: 26131326
Basic Res Cardiol. 2013 Jan;108(1):313
pubmed: 23184393
Circ Res. 2013 Feb 1;112(3):510-22
pubmed: 23250986
Acta Pharmacol Sin. 2018 Jan;39(1):1-11
pubmed: 28713160
Biomed Res Int. 2016;2016:3182764
pubmed: 27243031
Life (Basel). 2022 Aug 08;12(8):
pubmed: 36013381
BMC Endocr Disord. 2010 Apr 07;10:5
pubmed: 20374643
Circulation. 2002 Nov 26;106(22):2781-6
pubmed: 12451003
Hypertension. 2005 Apr;45(4):526-9
pubmed: 15767470
Diabet Med. 2009 Feb;26(2):134-41
pubmed: 19236615
Eur J Vasc Endovasc Surg. 2011 Sep;42 Suppl 1:S4-6
pubmed: 21855019
Diabetes Ther. 2022 Apr;13(4):679-690
pubmed: 34894328
Future Cardiol. 2018 Nov;14(6):491-509
pubmed: 30409037
High Blood Press Cardiovasc Prev. 2018 Dec;25(4):369-378
pubmed: 30203268
Eye (Lond). 2006 May;20(5):546-52
pubmed: 15905870
Am Heart J. 2006 Dec;152(6):1051.e1-8
pubmed: 17161050
Diabetes Metab Syndr Obes. 2021 Aug 10;14:3567-3602
pubmed: 34413662
Diabetes Care. 2013 Jan;36 Suppl 1:S67-74
pubmed: 23264425
BMC Med. 2017 Jul 19;15(1):131
pubmed: 28720102
J Diabetes. 2012 Jun;4(2):140-6
pubmed: 22078109
Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3422-7
pubmed: 10725398
Cardiovasc Diabetol. 2016 Jun 18;15:88
pubmed: 27316923
Am J Hypertens. 2015 Jan;28(1):22-9
pubmed: 24994608
Circ Res. 2009 Jan 2;104(1):32-40
pubmed: 19023133
Cell Death Dis. 2020 Jul 13;11(7):526
pubmed: 32661238
Ann Hematol. 2013 Sep;92(9):1189-94
pubmed: 23625296
PLoS One. 2015 Jul 31;10(7):e0134718
pubmed: 26230390
Diabetes Obes Metab. 2020 Jul;22(7):1220-1225
pubmed: 32166899
Cardiovasc Diabetol. 2014 Jul 16;13:111
pubmed: 25027585
Cell Biol Int. 2023 Jul;47(7):1267-1280
pubmed: 37017413
J Clin Invest. 2007 May;117(5):1249-59
pubmed: 17476357
Lancet. 2013 Oct 19;382(9901):1329-40
pubmed: 23915883
Acta Cardiol Sin. 2014 Sep;30(5):375-81
pubmed: 27122814
Nat Rev Nephrol. 2020 Apr;16(4):206-222
pubmed: 31942046
Nanomaterials (Basel). 2022 Oct 25;12(21):
pubmed: 36364516
Exp Clin Endocrinol Diabetes. 2017 Jun;125(6):400-407
pubmed: 28407661
N Engl J Med. 2016 Jul 28;375(4):380-2
pubmed: 27331286
Int J Cardiol. 2013 Sep 1;167(5):1688-95
pubmed: 23171577
Mol Metab. 2019 Sep;27S:S139-S146
pubmed: 31500825
Indian J Endocrinol Metab. 2016 Jul-Aug;20(4):546-51
pubmed: 27366724
Nephron Clin Pract. 2011;118(3):c309-14
pubmed: 21252582
Diabetologia. 2011 Aug;54(8):1946-56
pubmed: 21614571
J Cell Mol Med. 2022 Jan;26(2):306-311
pubmed: 34904385
Diabetes. 2011 Feb;60(2):652-61
pubmed: 21270275
Diabetes Obes Metab. 2011 Aug;13(8):718-25
pubmed: 21410861
Br J Pharmacol. 2009 Dec;158(8):1865-73
pubmed: 19917066
J Atheroscler Thromb. 2018 Jan 1;25(1):27-39
pubmed: 28966336
Atherosclerosis. 2005 Nov;183(1):163-7
pubmed: 15907852
Cell Transplant. 2018 May;27(5):786-795
pubmed: 29882417
Diabetes Care. 2018 Jan;41(Suppl 1):S86-S104
pubmed: 29222380
Diabetes Metab J. 2021 Sep;45(5):641-654
pubmed: 34610719
J Intern Med. 2010 Apr;267(4):385-93
pubmed: 19754853
Chin Med Sci J. 2011 Jun;26(2):69-76
pubmed: 21703113
World J Diabetes. 2015 Oct 10;6(13):1246-58
pubmed: 26468341
Phys Ther. 2008 Nov;88(11):1254-64
pubmed: 18801858
Am J Med. 2019 Oct;132(10):1133-1141
pubmed: 31150643
Diabetes Obes Metab. 2020 Apr;22 Suppl 1:3-15
pubmed: 32267079
Am J Transl Res. 2016 May 15;8(5):2169-78
pubmed: 27347324
Diabetologia. 2022 Feb;65(2):275-285
pubmed: 34718834
Int J Mol Sci. 2021 Nov 28;22(23):
pubmed: 34884679
J Cardiovasc Pharmacol Ther. 2009 Mar;14(1):14-21
pubmed: 19158317
Stem Cell Res Ther. 2020 Oct 15;11(1):441
pubmed: 33059750
Diabetologia. 2010 Oct;53(10):2129-33
pubmed: 20607514
Cardiovasc Drugs Ther. 2022 Feb;36(1):85-92
pubmed: 33394363
Metabolism. 2016 Jun;65(6):852-62
pubmed: 27173464
Biomed Res Int. 2017;2017:7839101
pubmed: 29238721
J Mol Cell Cardiol. 2017 Apr;105:12-23
pubmed: 28223221
Postgrad Med. 2020 Nov;132(8):676-686
pubmed: 32543261
Diabetes Care. 2003 Dec;26(12):3333-41
pubmed: 14633825
Endocrine. 2015 Dec;50(3):659-64
pubmed: 26209038
J Cell Biochem. 2019 May;120(5):7115-7124
pubmed: 30378162
Exp Clin Endocrinol Diabetes. 2019 Apr;127(4):215-219
pubmed: 29558784
Cardiovasc Diabetol. 2017 Feb 23;16(1):27
pubmed: 28231835
J Cell Mol Med. 2018 Jan;22(1):89-100
pubmed: 28799229
Eur Heart J. 2021 Jun 14;42(23):2235-2259
pubmed: 33764414
Diabetes. 2012 Apr;61(4):908-14
pubmed: 22338095
N Engl J Med. 2009 Jan 8;360(2):129-39
pubmed: 19092145
Diabetes Metab Syndr. 2015 Oct-Dec;9(4):305-9
pubmed: 25470647
Am J Pathol. 2021 Jan;191(1):52-65
pubmed: 33069720
Circulation. 2012 Jun 26;125(25):3220-8
pubmed: 22733336
Circulation. 2007 Jul 10;116(2):163-73
pubmed: 17592079
Cells. 2022 May 18;11(10):
pubmed: 35626716
Arterioscler Thromb Vasc Biol. 2004 Feb;24(2):288-93
pubmed: 14699017
Vasc Med. 2016 Feb;21(1):3-11
pubmed: 26511986
Hum Gene Ther Methods. 2013 Jun;24(3):171-84
pubmed: 23570242
Endocrine. 2018 Oct;62(1):263-266
pubmed: 30062543
Diabetologia. 2008 Jul;51(7):1296-305
pubmed: 18286257
Curr Diabetes Rev. 2006 Feb;2(1):71-98
pubmed: 18220619
Circ Res. 2016 May 27;118(11):1771-85
pubmed: 27230641
Invest Ophthalmol Vis Sci. 2015 Jun;56(6):4090-8
pubmed: 26114486
Diabetes. 2020 Aug;69(8):1779-1792
pubmed: 32404351
Diabetes. 2015 Apr;64(4):1407-19
pubmed: 25368097
Arterioscler Thromb Vasc Biol. 2005 Apr;25(4):698-703
pubmed: 15662022
Biomed Pharmacother. 2021 Nov;143:112183
pubmed: 34560536
Circ Res. 2016 Aug 5;119(4):564-71
pubmed: 27267067
Microvasc Res. 2011 Nov;82(3):227-36
pubmed: 21964072
Front Biosci (Landmark Ed). 2009 Jan 01;14(9):3608-18
pubmed: 19273297
Front Pharmacol. 2022 Aug 09;13:953691
pubmed: 36016568
PLoS One. 2014 Apr 08;9(4):e93965
pubmed: 24713821
Cardiovasc Diabetol. 2016 Aug 26;15(1):116
pubmed: 27561827
Sci Rep. 2021 Jul 15;11(1):14502
pubmed: 34267242
Cardiovasc Diabetol. 2018 May 3;17(1):65
pubmed: 29724198
Int J Clin Pharmacol Ther. 2020 Sep;58(9):491-503
pubmed: 32567544
Diabetes Obes Metab. 2010 Jul;12(7):570-83
pubmed: 20590732
Diabetes Obes Metab. 2019 Mar;21(3):467-478
pubmed: 30280465
Endocrinol Metab Clin North Am. 2018 Mar;47(1):51-63
pubmed: 29407056
Cardiovasc Diabetol. 2022 May 14;21(1):74
pubmed: 35568946
Stem Cells Int. 2016;2016:8043792
pubmed: 26839569
Diabetes Metab Syndr Obes. 2017 Aug 14;10:345-361
pubmed: 28860833
Cardiovasc Diabetol. 2021 Feb 13;20(1):44
pubmed: 33581737
Eur J Clin Pharmacol. 2014 Oct;70(10):1181-93
pubmed: 25048407
Diabetes Metab Syndr Obes. 2023 Apr 13;16:1043-1054
pubmed: 37077576
Vascul Pharmacol. 2016 Aug;83:10-6
pubmed: 26187355
Int J Cardiol. 2017 Oct 1;244:112-118
pubmed: 28668399
Am J Pathol. 2017 Jan;187(1):9-19
pubmed: 27846381
Sci Rep. 2021 May 6;11(1):9659
pubmed: 33958634
Growth Factors. 2014 Jun;32(3-4):83-116
pubmed: 24712317
Int J Mol Sci. 2020 Aug 30;21(17):
pubmed: 32872570
Diabetes Metab Res Rev. 2012 Jul;28(5):462-73
pubmed: 22492468
Diabetes Care. 2020 Apr;43(4):843-851
pubmed: 31988066
Rev Diabet Stud. 2015 Spring-Summer;12(1-2):48-62
pubmed: 26676661
Vascul Pharmacol. 2015 Apr-Jun;67-69:21-9
pubmed: 25483979
Front Med (Lausanne). 2018 Oct 16;5:273
pubmed: 30460233
World J Diabetes. 2021 Jun 15;12(6):827-838
pubmed: 34168731
Front Endocrinol (Lausanne). 2014 Apr 09;5:44
pubmed: 24782825
Acta Diabetol. 2019 Jul;56(7):785-795
pubmed: 30859314
Int J Mol Sci. 2020 Mar 06;21(5):
pubmed: 32155866
Biochem Biophys Res Commun. 2009 Apr 3;381(2):192-7
pubmed: 19232321
J Mol Med (Berl). 2022 Nov;100(11):1569-1585
pubmed: 36094536
PLoS One. 2015 Mar 30;10(3):e0122022
pubmed: 25822410
Cells. 2022 Nov 29;11(23):
pubmed: 36497087
Oncotarget. 2018 Apr 3;9(25):17858-17866
pubmed: 29707151
Diabetes Metab Syndr Obes. 2020 Mar 18;13:777-784
pubmed: 32256094
Cardiovasc Diabetol. 2014 Oct 11;13:137
pubmed: 25300286
Physiol Rev. 2013 Jan;93(1):137-88
pubmed: 23303908
PeerJ. 2020 Jul 7;8:e9306
pubmed: 32704438
J Clin Endocrinol Metab. 2018 Oct 1;103(10):3773-3782
pubmed: 30113651