Chronic Recurrent Multifocal Osteomyelitis.

Humans Osteomyelitis / diagnostic imaging Diphosphonates / therapeutic use Magnetic Resonance Imaging Chronic Disease
Bone pain CNO CRMO Chronic recurrent multifocal osteomyelitis Whole-body MRI

Journal

The Medical clinics of North America
ISSN: 1557-9859
Titre abrégé: Med Clin North Am
Pays: United States
ID NLM: 2985236R

Informations de publication

Date de publication:
Jan 2024
Historique:
medline: 13 11 2023
pubmed: 12 11 2023
entrez: 11 11 2023
Statut: ppublish

Résumé

Chronic recurrent multifocal osteomyelitis (CRMO) is an underrecognized autoinflammatory disease affecting the skeletal system. Its vague symptoms are often first attributed to growing pains, infection, or malignancy, which can lead to a delay in diagnosis for days to years. Untreated CRMO has the potential to cause debilitating skeletal deformities, arthritis, and chronic pain; hence early recognition and treatment are paramount. MRI is the gold standard for diagnosis. Treatment consists of various antiinflammatory medications and may also include bisphosphonates if vulnerable skeletal sites are involved. Even when treated, the disease may have a relapsing course lasting years.

Identifiants

DOI: 10.1016/j.mcna.2023.05.022 PMID: 37951653
pubmed: 37951653
pii: S0025-7125(23)00082-2
doi: 10.1016/j.mcna.2023.05.022
pii:
doi:

Substances chimiques

Diphosphonates 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

227-239

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Bridget A Rafferty (BA)

Medical College of Wisconsin, 8701 W. Watertown Plank Road, Milwaukee, WI 53226, USA.

Pooja Thakrar (P)

Medical College of Wisconsin/Children's Wisconsin, 9000 W. Wisconsin Avenue, MS-721, Milwaukee, WI 53226, USA. Electronic address: pthakrar@childrenswi.org.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Chronic Recurrent Multifocal Osteomyelitis.
questionsmedicales.fr › Maladies ostéomusculaires › Maladies osseuses › Infections osseuses › Ostéomyélite › Chronic Recurrent Multifocal Osteomyelitis.
questionsmedicales.fr › Composés chimiques organiques › Composés organiques du phosphore › Phosphonates › Diphosphonates › Chronic Recurrent Multifocal Osteomyelitis.
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Imagerie par résonance magnétique › Chronic Recurrent Multifocal Osteomyelitis.
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Caractéristiques de la maladie › Maladie chronique › Chronic Recurrent Multifocal Osteomyelitis.