Immunotherapy and Liver Transplantation: The Future or the Failure?

Humans Carcinoma, Hepatocellular / surgery Liver Neoplasms / surgery Liver Transplantation Treatment Outcome Immunotherapy Neoplasm Recurrence, Local / pathology
Hepatocellular carcinoma Immunotherapy Liver transplantation Outcomes Rejection

Journal

The Surgical clinics of North America
ISSN: 1558-3171
Titre abrégé: Surg Clin North Am
Pays: United States
ID NLM: 0074243

Informations de publication

Date de publication:
Feb 2024
Historique:
medline: 14 11 2023
pubmed: 13 11 2023
entrez: 12 11 2023
Statut: ppublish

Résumé

A quarter century has passed since the milestone study by Mazzaferro and colleagues on liver transplantation (LT) for hepatocellular carcinoma (HCC). The increasing demand for LT for HCC has led to the continued efforts to expand LT indications. Downstaging to within Milan criteria has been incorporated into the organ allocation policy for HCC in the United States in 2017 and provides acceptable long-term survival. The present review focuses on the rationale of neoadjuvant immune checkpoint inhibitor (ICI) in HCC, the experience of ICI in the pre- and posttransplant setting.

Identifiants

DOI: 10.1016/j.suc.2023.07.009 PMID: 37953034
pubmed: 37953034
pii: S0039-6109(23)00121-4
doi: 10.1016/j.suc.2023.07.009
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

163-182

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Parissa Tabrizian (P)

Liver Transplant and Hepatobiliary Surgery, Recanati/Miller Transplantation Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy, New York, NY 10029, USA. Electronic address: parissa.tabrizian@mountsinai.org.

Allen Yu (A)

Liver Transplant and Hepatobiliary Surgery, Recanati/Miller Transplantation Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy, New York, NY 10029, USA.

Neha Debnath (N)

Liver Transplant and Hepatobiliary Surgery, Recanati/Miller Transplantation Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy, New York, NY 10029, USA.

Bryan Myers (B)

Liver Transplant and Hepatobiliary Surgery, Recanati/Miller Transplantation Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy, New York, NY 10029, USA.

Thomas Marron (T)

Liver Transplant and Hepatobiliary Surgery, Recanati/Miller Transplantation Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy, New York, NY 10029, USA.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Immunotherapy and Liver Transplantation: The...
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies du foie › Tumeurs du foie › Carcinome hépatocellulaire › Immunotherapy and Liver Transplantation: The...
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies du foie › Tumeurs du foie › Immunotherapy and Liver Transplantation: The...
questionsmedicales.fr › Procédures de chirurgie opératoire › Transplantation › Transplantation de tissu › Transplantation hépatique › Immunotherapy and Liver Transplantation: The...
questionsmedicales.fr › Qualité, accès, évaluation des soins de santé › Qualité des soins de santé › Mécanismes d'évaluation des soins de santé › Évaluation des résultats et des processus en soins de santé › Évaluation de résultat (soins) › Résultat thérapeutique › Immunotherapy and Liver Transplantation: The...
questionsmedicales.fr › Thérapeutique › Biothérapie › Immunothérapie › Immunotherapy and Liver Transplantation: The...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Processus néoplasiques › Récidive tumorale locale › Immunotherapy and Liver Transplantation: The...