Liver Transplant for Intrahepatic Cholangiocarcinoma.

Humans Liver Transplantation / methods Bile Duct Neoplasms / surgery Cholangiocarcinoma / surgery Neoadjuvant Therapy Bile Ducts, Intrahepatic / surgery
Intrahepatic cholangiocarcinoma Liver resection Liver transplant Transplant oncology

Journal

The Surgical clinics of North America
ISSN: 1558-3171
Titre abrégé: Surg Clin North Am
Pays: United States
ID NLM: 0074243

Informations de publication

Date de publication:
Feb 2024
Historique:
medline: 14 11 2023
pubmed: 13 11 2023
entrez: 12 11 2023
Statut: ppublish

Résumé

Intrahepatic cholangiocarcinoma (iCCA) tends to be asymptomatic until late stages, leading most of the patients to present at advanced stages of the disease. A combination of medical and surgical therapy is crucial for patient management. Historically, poor outcomes resulted in liver transplantation being formally contraindicated for patients with iCCA; however, recent advances in patient selection and neoadjuvant therapy have resulted in a paradigm shift in liver transplant oncology. As a result, the feasibility of liver transplantation for iCCA is being reevaluated by several centers as a therapeutic alternative for select patients with locally advanced unresectable disease.

Identifiants

DOI: 10.1016/j.suc.2023.07.006 PMID: 37953037
pubmed: 37953037
pii: S0039-6109(23)00116-0
doi: 10.1016/j.suc.2023.07.006
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

215-225

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Olanrewaju A Eletta (OA)

Department of Surgery, Rutgers Robert Wood Johnson Medical School, 125 Paterson Street, MEB 596, New Brunswick, NJ 08901, USA.

Guergana G Panayotova (GG)

Division of Transplant and HPB Surgery, Department of Surgery Rutgers, New Jersey Medical School, 185 South Orange Avenue, Newark, NJ 07103, USA.

Keri E Lunsford (KE)

Division of Transplant and HPB Surgery, Department of Surgery Rutgers, New Jersey Medical School, 185 South Orange Avenue, Newark, NJ 07103, USA. Electronic address: keri.lunsford@rutgers.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Liver Transplant for Intrahepatic Cholangiocarcinoma.
questionsmedicales.fr › Procédures de chirurgie opératoire › Transplantation › Transplantation de tissu › Transplantation hépatique › Liver Transplant for Intrahepatic Cholangiocarcinoma.
questionsmedicales.fr › Maladies de l'appareil digestif › Tumeurs de l'appareil digestif › Tumeurs des voies biliaires › Tumeurs des canaux biliaires › Liver Transplant for Intrahepatic Cholangiocarcinoma.
questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Tumeurs épithéliales épidermoïdes et glandulaires › Carcinomes › Adénocarcinome › Cholangiocarcinome › Liver Transplant for Intrahepatic Cholangiocarcinoma.
questionsmedicales.fr › Thérapeutique › Association thérapeutique › Traitement néoadjuvant › Liver Transplant for Intrahepatic Cholangiocarcinoma.
questionsmedicales.fr › Système digestif › Foie › Conduits biliaires intrahépatiques › Liver Transplant for Intrahepatic Cholangiocarcinoma.