Donor Viral Hepatitis and Liver Transplantation.

Humans Liver Transplantation Antiviral Agents / therapeutic use Hepatitis C, Chronic / drug therapy Hepatitis C / drug therapy Tissue Donors Hepatitis, Viral, Human / drug therapy
Hepatitis B Hepatitis C Liver Transplantation

Journal

The Surgical clinics of North America
ISSN: 1558-3171
Titre abrégé: Surg Clin North Am
Pays: United States
ID NLM: 0074243

Informations de publication

Date de publication:
Feb 2024
Historique:
medline: 14 11 2023
pubmed: 13 11 2023
entrez: 12 11 2023
Statut: ppublish

Résumé

Despite increasing numbers of organ transplants completed each year, there continues to be an organ shortage in liver transplantation. This has led to the utilization of previously discarded or "marginal" allografts, such as those from donors with hepatitis C virus (HCV) or hepatitis B virus (HBV). The advent of direct acting antivirals and nucleos(t)ide analogs has allowed these allografts to be safely transplanted regardless of the recipients' hepatitis status with comparable graft and patient survival. Recent advances have even allowed usage of actively viremic donors with similar graft and patient outcomes. This article presents an overview of the use of HCV positive and HBV positive allografts.

Identifiants

DOI: 10.1016/j.suc.2023.07.002 PMID: 37953041
pubmed: 37953041
pii: S0039-6109(23)00112-3
doi: 10.1016/j.suc.2023.07.002
pii:
doi:

Substances chimiques

Antiviral Agents 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

67-77

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Sara-Catherine Whitney Zingg (SW)

Department of Surgery, University of Cincinnati College of Medicine, 231 Albert Sabin Way, ML 0558, Cincinnati, OH 45267, USA. Electronic address: https://twitter.com/transplant_u.

Kristina Lemon (K)

Department of Surgery, University of Cincinnati College of Medicine, 231 Albert Sabin Way, ML 0558, Cincinnati, OH 45267, USA; Division of Transplantation, University of Cincinnati School of Mediicne, 231 Albert Sabin Way, ML 0558, Cincinnati, OH 45267, USA. Electronic address: lemonkh@ucmail.uc.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Donor Viral Hepatitis and Liver Transplantation.
questionsmedicales.fr › Procédures de chirurgie opératoire › Transplantation › Transplantation de tissu › Transplantation hépatique › Donor Viral Hepatitis and Liver Transplantation.
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiviraux › Donor Viral Hepatitis and Liver Transplantation.
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Caractéristiques de la maladie › Maladie chronique › Hépatite chronique › Hépatite C chronique › Donor Viral Hepatitis and Liver Transplantation.
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies du foie › Hépatite › Hépatites virales humaines › Hépatite C › Donor Viral Hepatitis and Liver Transplantation.
questionsmedicales.fr › Personnes › Donneurs de tissus › Donor Viral Hepatitis and Liver Transplantation.
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies du foie › Hépatite › Hépatites virales humaines › Donor Viral Hepatitis and Liver Transplantation.