Association of Neighborhood-Level Material Deprivation with Adverse Outcomes and Processes of Care Among Patients with Heart Failure in a Single-Payer Healthcare System: A Population-Based Cohort Study.


Journal

European journal of heart failure
ISSN: 1879-0844
Titre abrégé: Eur J Heart Fail
Pays: England
ID NLM: 100887595

Informations de publication

Date de publication:
13 Nov 2023
Historique:
revised: 10 10 2023
received: 26 07 2023
accepted: 07 11 2023
medline: 13 11 2023
pubmed: 13 11 2023
entrez: 13 11 2023
Statut: aheadofprint

Résumé

We studied the association between neighborhood material deprivation, a metric estimating inability to attain basic material needs, with outcomes and processes of care among incident heart failure (HF) patients in a universal healthcare system. In a population-based retrospective study (2007-2019), we examined the association of material deprivation with one-year all-cause mortality, cause-specific hospitalization, and 90-day processes of care. Using cause-specific hazards regression we quantified the relative rate of events after multiple covariate adjustment, stratifying by age ≤65 or ≥66 years. Among 395,763 patients (median age 76 [IQR 66-84] years, 47% women), there was significant interaction between age and deprivation quintile for mortality/hospitalization outcomes (P≤0.001). Younger residents (age ≤65 years) of the most versus least deprived neighborhoods had higher hazards of all-cause death (HR 1.19 [95%CI, 1.10-1.29]) and cardiovascular hospitalization (HR 1.29 [95%CI, 1.19-1.39]). Older individuals (≥66 years) in the most deprived neighbourhoods had significantly higher hazard of death (HR 1.11 [95%CI, 1.08-1.14]) and cardiovascular hospitalization (HR 1.13 [95%CI, 1.09-1.18]) compared to the least deprived. The magnitude of the association between deprivation and outcomes was amplified in the younger compared to the older age group. More deprived individuals in both age groups had a lower hazard of cardiology visits and advanced cardiac imaging (all P<0.001), while the most deprived of younger ages were less likely to undergo ICD/CRT-P implantation (P=0.023), compared to the least deprived. Patients with newly-diagnosed HF residing in the most deprived neighborhoods had worse outcomes and reduced access to care than those less deprived. This article is protected by copyright. All rights reserved.

Sections du résumé

BACKGROUND BACKGROUND
We studied the association between neighborhood material deprivation, a metric estimating inability to attain basic material needs, with outcomes and processes of care among incident heart failure (HF) patients in a universal healthcare system.
METHODS METHODS
In a population-based retrospective study (2007-2019), we examined the association of material deprivation with one-year all-cause mortality, cause-specific hospitalization, and 90-day processes of care. Using cause-specific hazards regression we quantified the relative rate of events after multiple covariate adjustment, stratifying by age ≤65 or ≥66 years.
RESULTS RESULTS
Among 395,763 patients (median age 76 [IQR 66-84] years, 47% women), there was significant interaction between age and deprivation quintile for mortality/hospitalization outcomes (P≤0.001). Younger residents (age ≤65 years) of the most versus least deprived neighborhoods had higher hazards of all-cause death (HR 1.19 [95%CI, 1.10-1.29]) and cardiovascular hospitalization (HR 1.29 [95%CI, 1.19-1.39]). Older individuals (≥66 years) in the most deprived neighbourhoods had significantly higher hazard of death (HR 1.11 [95%CI, 1.08-1.14]) and cardiovascular hospitalization (HR 1.13 [95%CI, 1.09-1.18]) compared to the least deprived. The magnitude of the association between deprivation and outcomes was amplified in the younger compared to the older age group. More deprived individuals in both age groups had a lower hazard of cardiology visits and advanced cardiac imaging (all P<0.001), while the most deprived of younger ages were less likely to undergo ICD/CRT-P implantation (P=0.023), compared to the least deprived.
CONCLUSION CONCLUSIONS
Patients with newly-diagnosed HF residing in the most deprived neighborhoods had worse outcomes and reduced access to care than those less deprived. This article is protected by copyright. All rights reserved.

Identifiants

pubmed: 37953731
doi: 10.1002/ejhf.3090
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

This article is protected by copyright. All rights reserved.

Auteurs

David Bobrowski (D)

Department of Medicine, University of Toronto, Toronto, Canada.

Andrew Dorovenis (A)

Royal College of Surgeons in Ireland, Dublin, Ireland.

Husam Abdel-Qadir (H)

Department of Medicine, University of Toronto, Toronto, Canada.
Women's College Hospital, Toronto, Canada.
University Health Network, Toronto, Canada.
ICES (formerly known as the Institute for Clinical Evaluative Sciences), Toronto, Canada.
Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada.

Candace D McNaughton (CD)

Department of Medicine, University of Toronto, Toronto, Canada.
ICES (formerly known as the Institute for Clinical Evaluative Sciences), Toronto, Canada.
Sunnybrook Health Sciences Centre, Toronto, Canada.

Rea Alonzo (R)

ICES (formerly known as the Institute for Clinical Evaluative Sciences), Toronto, Canada.

Jiming Fang (J)

ICES (formerly known as the Institute for Clinical Evaluative Sciences), Toronto, Canada.

Peter C Austin (PC)

ICES (formerly known as the Institute for Clinical Evaluative Sciences), Toronto, Canada.
Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada.

Jacob A Udell (JA)

Department of Medicine, University of Toronto, Toronto, Canada.
Women's College Hospital, Toronto, Canada.
University Health Network, Toronto, Canada.
ICES (formerly known as the Institute for Clinical Evaluative Sciences), Toronto, Canada.
Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada.

Cynthia A Jackevicius (CA)

University Health Network, Toronto, Canada.
ICES (formerly known as the Institute for Clinical Evaluative Sciences), Toronto, Canada.
Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada.
Western University of Health Sciences, Pomona, California.

David A Alter (DA)

Department of Medicine, University of Toronto, Toronto, Canada.
University Health Network, Toronto, Canada.
ICES (formerly known as the Institute for Clinical Evaluative Sciences), Toronto, Canada.
Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada.

Clare L Atzema (CL)

Department of Medicine, University of Toronto, Toronto, Canada.
ICES (formerly known as the Institute for Clinical Evaluative Sciences), Toronto, Canada.
Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada.
Sunnybrook Health Sciences Centre, Toronto, Canada.

R Sacha Bhatia (RS)

Department of Medicine, University of Toronto, Toronto, Canada.
University Health Network, Toronto, Canada.

Gillian L Booth (GL)

Department of Medicine, University of Toronto, Toronto, Canada.
ICES (formerly known as the Institute for Clinical Evaluative Sciences), Toronto, Canada.
Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada.
Li Ka Shing Knowledge Institute of St Michael's Hospital, Toronto, Canada.

Andrew C T Ha (ACT)

Department of Medicine, University of Toronto, Toronto, Canada.
University Health Network, Toronto, Canada.

Sharon Johnston (S)

Departments of Family Medicine, University of Ottawa, Ottawa, Canada.
Institut du Savoir, Hôpital Montfort', Ottawa, Canada.

Irfan Dhalla (I)

Department of Medicine, University of Toronto, Toronto, Canada.
Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada.
Li Ka Shing Knowledge Institute of St Michael's Hospital, Toronto, Canada.

Moira K Kapral (MK)

Department of Medicine, University of Toronto, Toronto, Canada.
University Health Network, Toronto, Canada.
ICES (formerly known as the Institute for Clinical Evaluative Sciences), Toronto, Canada.
Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada.

Harlan M Krumholz (HM)

Center for Outcomes Research and Evaluation, Yale New Haven Hospital, New Haven, Connecticut.
Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.
Department of Health Policy and Management, Yale School of Public Health, New Haven, Connecticut.

Idan Roifman (I)

Department of Medicine, University of Toronto, Toronto, Canada.
ICES (formerly known as the Institute for Clinical Evaluative Sciences), Toronto, Canada.
Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada.
Sunnybrook Health Sciences Centre, Toronto, Canada.

Harindra C Wijeysundera (HC)

Department of Medicine, University of Toronto, Toronto, Canada.
ICES (formerly known as the Institute for Clinical Evaluative Sciences), Toronto, Canada.
Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada.
Sunnybrook Health Sciences Centre, Toronto, Canada.

Dennis T Ko (DT)

Department of Medicine, University of Toronto, Toronto, Canada.
ICES (formerly known as the Institute for Clinical Evaluative Sciences), Toronto, Canada.
Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada.
Sunnybrook Health Sciences Centre, Toronto, Canada.

Karen Tu (K)

University Health Network, Toronto, Canada.
Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada.
Department of Family and Community Medicine, University of Toronto, Toronto, Canada.
North York General Hospital, Toronto, Canada.

Heather J Ross (HJ)

Department of Medicine, University of Toronto, Toronto, Canada.
University Health Network, Toronto, Canada.

Michael J Schull (MJ)

Department of Medicine, University of Toronto, Toronto, Canada.
ICES (formerly known as the Institute for Clinical Evaluative Sciences), Toronto, Canada.
Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada.
Sunnybrook Health Sciences Centre, Toronto, Canada.

Douglas S Lee (DS)

Department of Medicine, University of Toronto, Toronto, Canada.
University Health Network, Toronto, Canada.
ICES (formerly known as the Institute for Clinical Evaluative Sciences), Toronto, Canada.
Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada.

Classifications MeSH