Amnion responses to intrauterine inflammation and effects of inhibition of TNF signaling in preterm Rhesus macaque.

Bioinformatics Immunology Omics

Journal

iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038

Informations de publication

Date de publication:
17 Nov 2023
Historique:
received: 28 02 2023
revised: 26 05 2023
accepted: 29 09 2023
medline: 13 11 2023
pubmed: 13 11 2023
entrez: 13 11 2023
Statut: epublish

Résumé

Intrauterine infection/inflammation (IUI) is a frequent complication of pregnancy leading to preterm labor and fetal inflammation. How inflammation is modulated at the maternal-fetal interface is unresolved. We compared transcriptomics of amnion (a fetal tissue in contact with amniotic fluid) in a preterm Rhesus macaque model of IUI induced by lipopolysaccharide with human cohorts of chorioamnionitis. Bulk RNA sequencing (RNA-seq) amnion transcriptomic profiles were remarkably similar in both Rhesus and human subjects and revealed that induction of key labor-mediating genes such as

Identifiants

DOI: 10.1016/j.isci.2023.108118 PMID: 37953944 PMC: PMC10637919
pubmed: 37953944
doi: 10.1016/j.isci.2023.108118
pii: S2589-0042(23)02195-8
pmc: PMC10637919
doi:

Types de publication

Journal Article

Langues

eng

Pagination

108118

Subventions

Organisme : NIEHS NIH HHS
ID : U01 ES029234
Pays : United States

Informations de copyright

© 2023 The Author(s).

Déclaration de conflit d'intérêts

The authors declare no competing interests.

Références

Mucosal Immunol. 2008 Nov;1(6):497-507
pubmed: 19079217
Hum Immunol. 2016 Sep;77(9):734-9
pubmed: 27476049
iScience. 2022 Jan 12;25(2):103759
pubmed: 35141503
Biol Reprod. 2015 Feb;92(2):56
pubmed: 25537373
Mol Hum Reprod. 2019 Apr 1;25(4):228-240
pubmed: 30753586
J Reprod Immunol. 2008 Oct;79(1):50-7
pubmed: 18550178
Br J Obstet Gynaecol. 1997 Sep;104(9):1087-91
pubmed: 9307541
Proc Natl Acad Sci U S A. 2017 Sep 12;114(37):E7786-E7795
pubmed: 28830992
Nat Commun. 2016 Apr 25;7:11414
pubmed: 27108815
Sci Adv. 2021 Jan 22;7(4):
pubmed: 33523942
Front Immunol. 2020 May 22;11:866
pubmed: 32528468
J Perinat Med. 1998;26(1):17-26
pubmed: 9595363
Front Immunol. 2020 Apr 03;11:558
pubmed: 32308656
Stem Cells. 2014 Jun;32(6):1408-19
pubmed: 24578244
Cytometry A. 2011 Aug;79(8):635-45
pubmed: 21735544
BMC Genomics. 2012 Mar 27;13:115
pubmed: 22448651
Stem Cells Dev. 2011 Dec;20(12):2115-26
pubmed: 21381973
PLoS One. 2012;7(4):e34707
pubmed: 22485186
Semin Perinatol. 2017 Nov;41(7):409-419
pubmed: 28807394
Cell Rep Methods. 2023 Jun 12;3(6):100498
pubmed: 37426759
Nature. 2018 Nov;563(7731):347-353
pubmed: 30429548
Bioinformatics. 2009 Jan 15;25(2):288-9
pubmed: 19033274
Nat Biotechnol. 2020 Dec;38(12):1408-1414
pubmed: 32747759
BMC Bioinformatics. 2013 Apr 15;14:128
pubmed: 23586463
Immunol Rev. 2012 Mar;246(1):346-58
pubmed: 22435565
Stem Cells. 2008 Jan;26(1):182-92
pubmed: 17901399
Mol Hum Reprod. 2001 Jun;7(6):581-6
pubmed: 11385114
Nat Rev Immunol. 2015 Jun;15(6):362-74
pubmed: 26008591
Science. 2014 Aug 15;345(6198):760-5
pubmed: 25124429
Placenta. 2018 Aug;68:9-14
pubmed: 30055672
BJOG. 2009 Jan;116(2):257-67
pubmed: 18947340
Placenta. 2008 Dec;29(12):995-1002
pubmed: 18952281
Am J Obstet Gynecol. 1985 Dec 15;153(8):899-903
pubmed: 4073165
J Infect Dis. 2020 Oct 13;222(10):1713-1722
pubmed: 32453818
Placenta. 2016 Jun;42:59-73
pubmed: 27238715
J Immunol. 2011 Sep 1;187(5):2766-74
pubmed: 21775685
Placenta. 2016 Feb;38:57-66
pubmed: 26907383
PLoS Biol. 2021 Sep 8;19(9):e3001385
pubmed: 34495952
Biol Reprod. 2008 Nov;79(5):954-61
pubmed: 18685129
Am J Obstet Gynecol. 2015 Dec;213(6):836.e1-836.e18
pubmed: 26232508
J Clin Endocrinol Metab. 2005 Jun;90(6):3534-43
pubmed: 15755849
Genome Res. 2017 Mar;27(3):349-361
pubmed: 28174237
PLoS One. 2014 Dec 03;9(12):e113799
pubmed: 25469638
Pharmacoepidemiol Drug Saf. 2020 Mar;29(3):316-327
pubmed: 32020767
Am J Respir Crit Care Med. 2001 Sep 15;164(6):982-8
pubmed: 11587983
JCI Insight. 2020 Dec 17;5(24):
pubmed: 33328385
Pediatr Dev Pathol. 2003 Sep-Oct;6(5):435-48
pubmed: 14708737
Mucosal Immunol. 2022 Apr;15(4):730-744
pubmed: 35314757
J Clin Endocrinol Metab. 2017 Apr 1;102(4):1261-1269
pubmed: 28388726
Am J Pathol. 2018 Sep;188(9):2004-2015
pubmed: 29981743
Mol Hum Reprod. 2017 Sep 1;23(9):628-645
pubmed: 28911210
Int J Mol Sci. 2021 Jan 19;22(2):
pubmed: 33478081
Cell Transplant. 2018 Jan;27(1):31-44
pubmed: 29562786
Reprod Sci. 2016 Jan;23(1):69-80
pubmed: 26156854
Am J Reprod Immunol. 2014 Nov;72(5):458-74
pubmed: 25078709
J Immunol. 2020 May 15;204(10):2651-2660
pubmed: 32238461
Am J Obstet Gynecol. 2006 Dec;195(6):1578-89
pubmed: 17132473
JCI Insight. 2018 Mar 22;3(6):
pubmed: 29563340
BMC Bioinformatics. 2019 Dec 30;20(1):743
pubmed: 31888436
Stem Cells Transl Med. 2018 Sep;7(9):628-635
pubmed: 30078207
Elife. 2019 Dec 12;8:
pubmed: 31829938
Sci Signal. 2020 Feb 11;13(618):
pubmed: 32047115
Curr Protoc Bioinformatics. 2017 Jun 27;58:8.23.1-8.23.16
pubmed: 28654729
Immunity. 2019 Nov 19;51(5):885-898.e7
pubmed: 31542340
Nature. 2019 May;569(7758):723-728
pubmed: 31043742
Lancet. 2008 Jan 5;371(9606):75-84
pubmed: 18177778

Auteurs

Pietro Presicce (P)

Divisions of Neonatology and Developmental Biology, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, CA, USA.

Monica Cappelletti (M)

Divisions of Neonatology and Developmental Biology, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, CA, USA.

Marco Morselli (M)

Department of Molecular, Cell and Developmental Biology Medicine at the University of California Los Angeles, Los Angeles, CA, USA.
Institute for Quantitative and Computational Biosciences - Collaboratory at the University of California Los Angeles, Los Angeles, CA, USA.

Feiyang Ma (F)

Department of Molecular, Cell and Developmental Biology Medicine at the University of California Los Angeles, Los Angeles, CA, USA.
Institute for Quantitative and Computational Biosciences - Collaboratory at the University of California Los Angeles, Los Angeles, CA, USA.

Paranthaman Senthamaraikannan (P)

Division of Neonatology/Pulmonary Biology, Cincinnati Children's Hospital Research Foundation, The University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Division of Immunobiology, Cincinnati Children's Hospital Research Foundation, The University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Giulia Protti (G)

Institute for Quantitative and Computational Biosciences - Collaboratory at the University of California Los Angeles, Los Angeles, CA, USA.
Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.

Brian B Nadel (BB)

Department of Molecular Cellular and Developmental Biology, and Institute for Genomics and Proteomics, University of California Los Angeles, Los Angeles, CA, USA.
California National Primate Research Center, University of California Davis, Davis, CA, USA.

Laila Aryan (L)

Division of Molecular Medicine, Department of Anesthesiology, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, CA, USA.

Mansoureh Eghbali (M)

Division of Molecular Medicine, Department of Anesthesiology, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, CA, USA.

Lukasz Salwinski (L)

UCLA-DOE Institute of Genomics and Proteomics, University of California Los Angeles, Los Angeles, CA, USA.

Neema Pithia (N)

Divisions of Neonatology and Developmental Biology, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, CA, USA.

Emily De Franco (E)

Department of Obstetrics/Gynecology, Maternal-Fetal Medicine, University of Cincinnati, Cincinnati, OH, USA.

Lisa A Miller (LA)

Department of Anatomy, Physiology, and Cell Biology, School of Veterinary Medicine, University of California Davis, CA, USA.

Matteo Pellegrini (M)

Department of Molecular, Cell and Developmental Biology Medicine at the University of California Los Angeles, Los Angeles, CA, USA.
Institute for Quantitative and Computational Biosciences - Collaboratory at the University of California Los Angeles, Los Angeles, CA, USA.

Alan H Jobe (AH)

Division of Neonatology/Pulmonary Biology, Cincinnati Children's Hospital Research Foundation, The University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Division of Immunobiology, Cincinnati Children's Hospital Research Foundation, The University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Claire A Chougnet (CA)

Division of Immunobiology, Cincinnati Children's Hospital Research Foundation, and the University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Suhas G Kallapur (SG)

Divisions of Neonatology and Developmental Biology, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, CA, USA.

Classifications MeSH