Advances in the Applications of Extracellular Vesicle for the Treatment of Skin Photoaging: A Comprehensive Review.
exosomes
extracellular vesicles
liposomes
skin photoaging
skin rejuvenation
stem cells
Journal
International journal of nanomedicine
ISSN: 1178-2013
Titre abrégé: Int J Nanomedicine
Pays: New Zealand
ID NLM: 101263847
Informations de publication
Date de publication:
2023
2023
Historique:
received:
02
08
2023
accepted:
27
10
2023
medline:
14
11
2023
pubmed:
13
11
2023
entrez:
13
11
2023
Statut:
epublish
Résumé
Skin photoaging is a complex biological process characterized by the accumulation of oxidative damage and structural changes in the skin, resulting from chronic exposure to ultraviolet (UV) radiation. Despite the growing demand for effective treatments, current therapeutic options for skin photoaging remain limited. However, emerging research has highlighted the potential of extracellular vesicles (EVs), including exosomes, micro-vesicles, apoptotic bodies and liposomes, as promising therapeutic agents in skin rejuvenation. EVs are involved in intercellular communication and can deliver bioactive molecules, including proteins, nucleic acids, and lipids, to recipient cells, thereby influencing various cellular processes. This comprehensive review aims to summarize the current research progress in the application of EVs for the treatment of skin photoaging, including their isolation and characterization methods, roles in skin homeostasis, therapeutic potential and clinical applications for skin photoaging. Additionally, challenges and future directions in EVs-based therapies for skin rejuvenation are discussed.
Identifiants
pubmed: 37954453
doi: 10.2147/IJN.S433611
pii: 433611
pmc: PMC10638935
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
6411-6423Informations de copyright
© 2023 Cai et al.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest in this work.
Références
J Extracell Vesicles. 2019 Jan 20;8(1):1565885
pubmed: 30719241
Semin Cutan Med Surg. 1996 Sep;15(3):177-88
pubmed: 8948536
Photodermatol Photoimmunol Photomed. 2023 May;39(3):235-245
pubmed: 35950642
Pharmaceuticals (Basel). 2021 Aug 18;14(8):
pubmed: 34451909
Stem Cell Res Ther. 2020 Jul 1;11(1):264
pubmed: 32611371
Int J Mol Sci. 2022 Oct 28;23(21):
pubmed: 36361857
Methods Mol Biol. 2018;1678:79-92
pubmed: 29071676
J Biomed Mater Res A. 2021 Oct;109(10):1849-1857
pubmed: 34060700
Biochem Pharmacol. 2017 Oct 15;142:1-12
pubmed: 28408343
Ther Deliv. 2021 Feb;12(2):145-158
pubmed: 33583219
Nat Protoc. 2021 Mar;16(3):1548-1580
pubmed: 33495626
Biomed Res Int. 2020 Dec 21;2020:6406395
pubmed: 33415151
JCI Insight. 2022 May 9;7(9):
pubmed: 35316219
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017 Sep;9(5):
pubmed: 28198148
Stem Cell Res Ther. 2022 Apr 8;13(1):147
pubmed: 35395929
Am J Clin Dermatol. 2016 Jun;17(3):265-76
pubmed: 26969582
Trends Cell Biol. 2023 Aug;33(8):667-681
pubmed: 36737375
Clin Interv Aging. 2006;1(4):327-48
pubmed: 18046911
Cells. 2022 Dec 01;11(23):
pubmed: 36497136
Cell Transplant. 2015;24(3):339-47
pubmed: 25622293
Adv Biosyst. 2019 Jun;3(6):e1800324
pubmed: 32648708
Acta Biomater. 2022 Jul 15;147:342-355
pubmed: 35580827
Pharmaceutics. 2021 Sep 23;13(10):
pubmed: 34683836
Physiol Rev. 2019 Jan 1;99(1):665-706
pubmed: 30475656
Semin Immunol. 2013 Nov 30;25(5):370-7
pubmed: 24268438
Int J Pharm. 2021 May 15;601:120571
pubmed: 33812967
Facial Plast Surg Clin North Am. 2022 Aug;30(3):331-346
pubmed: 35934435
Crit Rev Anal Chem. 2022;52(2):392-412
pubmed: 32799645
J Invest Dermatol. 2021 Apr;141(4S):1119-1126
pubmed: 33349436
Protoplasma. 2020 Jan;257(1):3-12
pubmed: 31468195
Front Immunol. 2023 Feb 28;14:1136098
pubmed: 36926346
Ageing Res Rev. 2020 May;59:101036
pubmed: 32105850
Arch Dermatol. 2002 Nov;138(11):1462-70
pubmed: 12437452
Plast Reconstr Surg. 2014 Apr;133(4):481e-490e
pubmed: 24675201
Subcell Biochem. 2021;97:19-43
pubmed: 33779912
Nat Commun. 2021 Jul 19;12(1):4389
pubmed: 34282141
Biomaterials. 2022 Aug;287:121644
pubmed: 35772350
Photodermatol Photoimmunol Photomed. 2022 May;38(3):191-196
pubmed: 34585779
Adv Drug Deliv Rev. 2018 Apr;129:394-406
pubmed: 29408181
Cells. 2019 Jul 15;8(7):
pubmed: 31311206
J Cosmet Dermatol. 2021 Nov;20(11):3427-3431
pubmed: 33655657
J Cell Biol. 2013 Feb 18;200(4):373-83
pubmed: 23420871
ACS Nano. 2019 Oct 22;13(10):11273-11282
pubmed: 31449388
Int J Environ Res Public Health. 2021 Feb 26;18(5):
pubmed: 33652987
Plast Reconstr Surg. 2006 Jun;117(7 Suppl):1e-S-32e-S
pubmed: 16801750
Cell Prolif. 2021 Dec;54(12):e13123
pubmed: 34609779
Oxid Med Cell Longev. 2022 Jan 4;2022:6037303
pubmed: 35028009
Head Neck Pathol. 2016 Jun;10(2):139-44
pubmed: 26975629
Tissue Eng Part B Rev. 2023 Jun;29(3):190-202
pubmed: 36200631
Curr Med Chem. 2018 Feb 13;25(5):606-635
pubmed: 28990515
J Neurooncol. 2013 May;113(1):1-11
pubmed: 23456661
J Control Release. 2022 Jul;347:533-543
pubmed: 35597405
Oxid Med Cell Longev. 2019 Dec 13;2019:8135985
pubmed: 31915514
Oxid Med Cell Longev. 2022 Aug 8;2022:6742792
pubmed: 35979398
Facial Plast Surg Clin North Am. 2022 Aug;30(3):291-300
pubmed: 35934431
Int J Nanomedicine. 2020 Apr 23;15:2859-2872
pubmed: 32368058
Free Radic Biol Med. 2017 Jun;107:110-124
pubmed: 28109890
Med Res Rev. 2022 Nov;42(6):2102-2125
pubmed: 35757979
Front Endocrinol (Lausanne). 2017 Jul 24;8:174
pubmed: 28790977
J Nanobiotechnology. 2022 Oct 21;20(1):455
pubmed: 36271377
Facial Plast Surg Clin North Am. 2020 Feb;28(1):87-100
pubmed: 31779945
Adv Drug Deliv Rev. 2020;154-155:102-122
pubmed: 32650041
Curr Med Chem. 2018;25(41):5782-5797
pubmed: 28933299
Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):E968-77
pubmed: 26858453
Curr Issues Mol Biol. 2022 Jan 21;44(2):526-540
pubmed: 35723322
Methods Mol Biol. 2017;1660:111-130
pubmed: 28828652
Facial Plast Surg Clin North Am. 2018 Nov;26(4):513-532
pubmed: 30213431
Photodermatol Photoimmunol Photomed. 2015 Mar;31(2):65-74
pubmed: 25351668
Photochem Photobiol Sci. 2020 Mar 1;19(3):406-414
pubmed: 32125331
Methods Mol Biol. 2017;1660:25-32
pubmed: 28828645
Cold Spring Harb Perspect Med. 2015 Jan 05;5(1):a015370
pubmed: 25561721
Drug Deliv. 2020 Dec;27(1):585-598
pubmed: 32264719
Photochem Photobiol Sci. 2023 Jan;22(1):135-146
pubmed: 36114328
Annu Rev Biochem. 2019 Jun 20;88:487-514
pubmed: 31220978
Int J Mol Sci. 2021 Apr 12;22(8):
pubmed: 33921444
Front Bioeng Biotechnol. 2022 Dec 09;10:1053217
pubmed: 36568307
Pharmacol Res. 2021 Apr;166:105490
pubmed: 33582246
Rejuvenation Res. 2021 Aug;24(4):283-293
pubmed: 33607932
Am J Reprod Immunol. 2021 Feb;85(2):e13367
pubmed: 33118232
Oxid Med Cell Longev. 2018 Aug 2;2018:1454936
pubmed: 30174780
Nat Biomed Eng. 2023 Jul;7(7):887-900
pubmed: 36635419
Front Bioeng Biotechnol. 2022 Nov 07;10:1043320
pubmed: 36420445
Exp Dermatol. 2014 Oct;23 Suppl 1:7-12
pubmed: 25234829
Stem Cell Res Ther. 2020 Nov 27;11(1):507
pubmed: 33246491
Int J Mol Sci. 2020 Sep 04;21(18):
pubmed: 32899828
Am J Clin Dermatol. 2021 Nov;22(6):819-828
pubmed: 34387824
Int J Mol Sci. 2021 Apr 08;22(8):
pubmed: 33917759
Theranostics. 2020 Aug 7;10(22):9937-9955
pubmed: 32929326
Arch Dermatol Res. 2022 Nov;314(9):823-838
pubmed: 34609598
Int J Mol Sci. 2018 Jun 09;19(6):
pubmed: 29890746
Nanomedicine (Lond). 2023 Feb;18(3):217-231
pubmed: 37125627
J Extracell Vesicles. 2021 Dec;10(14):e12175
pubmed: 34918479
J Pharm Biomed Anal. 2021 Jan 5;192:113642
pubmed: 33011580
Int J Mol Sci. 2022 Jun 16;23(12):
pubmed: 35743181
Mol Ther. 2021 Jan 6;29(1):13-31
pubmed: 33278566
J Drugs Dermatol. 2021 Sep 1;20(9):996-1003
pubmed: 34491027
Int J Mol Sci. 2022 Dec 06;23(23):
pubmed: 36499715
Adv Ther. 2022 Dec;39(12):5351-5375
pubmed: 36220974
Subcell Biochem. 2021;97:61-88
pubmed: 33779914