Development of photoreactive demineralized bone matrix 3D printing colloidal inks for bone tissue engineering.
3D printing
bone tissue engineering
colloidal hydrogels
demineralized bone matrix
Journal
Regenerative biomaterials
ISSN: 2056-3418
Titre abrégé: Regen Biomater
Pays: England
ID NLM: 101652150
Informations de publication
Date de publication:
2023
2023
Historique:
received:
02
08
2023
revised:
15
09
2023
accepted:
28
09
2023
medline:
13
11
2023
pubmed:
13
11
2023
entrez:
13
11
2023
Statut:
epublish
Résumé
Demineralized bone matrix (DBM) has been widely used clinically for dental, craniofacial and skeletal bone repair, as an osteoinductive and osteoconductive material. 3D printing (3DP) enables the creation of bone tissue engineering scaffolds with complex geometries and porosity. Photoreactive methacryloylated gelatin nanoparticles (GNP-MAs) 3DP inks have been developed, which display gel-like behavior for high print fidelity and are capable of post-printing photocrosslinking for control of scaffold swelling and degradation. Here, novel DBM nanoparticles (DBM-NPs, ∼400 nm) were fabricated and characterized prior to incorporation in 3DP inks. The objectives of this study were to determine how these DBM-NPs would influence the printability of composite colloidal 3DP inks, assess the impact of ultraviolet (UV) crosslinking on 3DP scaffold swelling and degradation and evaluate the osteogenic potential of DBM-NP-containing composite colloidal scaffolds. The addition of methacryloylated DBM-NPs (DBM-NP-MAs) to composite colloidal inks (100:0, 95:5 and 75:25 GNP-MA:DBM-NP-MA) did not significantly impact the rheological properties associated with printability, such as viscosity and shear recovery or photocrosslinking. UV crosslinking with a UV dosage of 3 J/cm
Identifiants
pubmed: 37954896
doi: 10.1093/rb/rbad090
pii: rbad090
pmc: PMC10634525
doi:
Types de publication
Journal Article
Langues
eng
Pagination
rbad090Informations de copyright
© The Author(s) 2023. Published by Oxford University Press.
Références
Connect Tissue Res. 2004;45(4-5):257-60
pubmed: 15763935
ACS Appl Mater Interfaces. 2014 Jun 25;6(12):9328-37
pubmed: 24865253
Sci Rep. 2019 May 3;9(1):6863
pubmed: 31053756
Biomaterials. 2020 Feb;230:119632
pubmed: 31761486
Adv Biol (Weinh). 2021 Jan;5(1):e202000135
pubmed: 33585837
Biomater Sci. 2019 May 28;7(6):2452-2467
pubmed: 30942200
Mater Sci Eng C Mater Biol Appl. 2020 Jul;112:110958
pubmed: 32409091
Tissue Eng Part A. 2020 Mar;26(5-6):239-252
pubmed: 31696784
Int J Spine Surg. 2021 Apr;15(s1):113-119
pubmed: 34376500
Differentiation. 2012 Jun;83(5):249-59
pubmed: 22469856
Sci Rep. 2016 Aug 09;6:31036
pubmed: 27503340
J Mater Chem B. 2021 Jan 21;9(2):479-493
pubmed: 33289774
J Vet Sci. 2015;16(3):381-4
pubmed: 26040617
J Tissue Eng Regen Med. 2020 Mar;14(3):475-485
pubmed: 32011080
J Oral Maxillofac Surg. 2008 Feb;66(2):235-45
pubmed: 18201602
Biomacromolecules. 2018 Jan 8;19(1):42-52
pubmed: 29211461
Clin Plast Surg. 1987 Jan;14(1):27-35
pubmed: 3545620
Carbohydr Polym. 2020 Dec 15;250:116914
pubmed: 33049834
J Mater Chem B. 2021 Feb 25;9(7):1858-1866
pubmed: 33533364
Mater Sci Eng C Mater Biol Appl. 2021 May;124:112065
pubmed: 33947558
Materials (Basel). 2019 Apr 26;12(9):
pubmed: 31027339
Biointerphases. 2015 Dec 06;10(4):041001
pubmed: 26443012
Biofabrication. 2021 Apr 09;13(3):
pubmed: 35130535
ACS Appl Mater Interfaces. 2019 Oct 30;11(43):39449-39458
pubmed: 31584255
Biofabrication. 2022 Aug 26;14(4):
pubmed: 35931060
Annu Rev Biochem. 2009;78:929-58
pubmed: 19344236
Ann Periodontol. 2003 Dec;8(1):321-7
pubmed: 14971259
Pathol Biol (Paris). 2009 Jun;57(4):318-23
pubmed: 18842361
Mater Today Bio. 2022 Sep 09;16:100422
pubmed: 36133794
Annu Rev Chem Biomol Eng. 2019 Jun 7;10:17-42
pubmed: 30951639
Expert Opin Biol Ther. 2009 Jan;9(1):9-19
pubmed: 19063689
J Periodontol. 1997 Nov;68(11):1085-92
pubmed: 9407401
Connect Tissue Res. 2006;47(5):271-7
pubmed: 17118749
Birth Defects Res C Embryo Today. 2010 Mar;90(1):75-85
pubmed: 20301221
Gen Dent. 2000 May-Jun;48(3):304-12
pubmed: 11199597
Adv Drug Deliv Rev. 2012 Sep;64(12):1063-77
pubmed: 22728914
Eur Cell Mater. 2015 Apr 19;29:224-36; discussion 236
pubmed: 25890595
Acta Biomater. 2023 Jan 1;155:99-112
pubmed: 36384222
Front Neurosci. 2020 Oct 26;14:538404
pubmed: 33192240
Biomaterials. 2021 Jul;274:120871
pubmed: 34029914
Tissue Eng Part C Methods. 2017 Apr;23(4):243-250
pubmed: 28406755
J Funct Biomater. 2021 Oct 04;12(4):
pubmed: 34698233
Acta Biomater. 2014 Nov;10(11):4574-4582
pubmed: 25046637
Ann Rheum Dis. 2000 Jun;59(6):455-61
pubmed: 10834863
Tissue Eng Part A. 2009 Jan;15(1):13-21
pubmed: 18652539
Organogenesis. 2012 Oct-Dec;8(4):114-24
pubmed: 23247591
Acta Biomater. 2021 Jun;127:146-158
pubmed: 33831576
Orthop Surg. 2019 Oct;11(5):725-737
pubmed: 31496049
Biomaterials. 2011 Apr;32(12):3233-43
pubmed: 21296410
Tissue Eng Part A. 2010 Mar;16(3):815-27
pubmed: 19778183
Biomaterials. 2008 Mar;29(9):1189-97
pubmed: 18083224
Nat Commun. 2014 Jun 02;5:3935
pubmed: 24887553
Tissue Eng Part A. 2020 Feb;26(3-4):157-166
pubmed: 31469055
Spine (Phila Pa 1976). 2022 Jan 1;47(1):82-89
pubmed: 34115714
Prog Polym Sci. 2019 Apr;91:126-140
pubmed: 31571701