Local field potentials, spiking activity, and receptive fields in human visual cortex.

human visual cortex intracranial EEG local field potential receptive field spiking activity

Journal

Science China. Life sciences
ISSN: 1869-1889
Titre abrégé: Sci China Life Sci
Pays: China
ID NLM: 101529880

Informations de publication

Date de publication:
09 Nov 2023
Historique:
received: 29 06 2023
accepted: 21 08 2023
medline: 14 11 2023
pubmed: 14 11 2023
entrez: 13 11 2023
Statut: aheadofprint

Résumé

The concept of receptive field (RF) is central to sensory neuroscience. Neuronal RF properties have been substantially studied in animals, while those in humans remain nearly unexplored. Here, we measured neuronal RFs with intracranial local field potentials (LFPs) and spiking activity in human visual cortex (V1/V2/V3). We recorded LFPs via macro-contacts and discovered that RF sizes estimated from low-frequency activity (LFA, 0.5-30 Hz) were larger than those estimated from low-gamma activity (LGA, 30-60 Hz) and high-gamma activity (HGA, 60-150 Hz). We then took a rare opportunity to record LFPs and spiking activity via microwires in V1 simultaneously. We found that RF sizes and temporal profiles measured from LGA and HGA closely matched those from spiking activity. In sum, this study reveals that spiking activity of neurons in human visual cortex could be well approximated by LGA and HGA in RF estimation and temporal profile measurement, implying the pivotal functions of LGA and HGA in early visual information processing.

Identifiants

pubmed: 37957484
doi: 10.1007/s11427-023-2436-x
pii: 10.1007/s11427-023-2436-x
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2023. Science China Press.

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pubmed: 31747389 pmcid: 6892546 doi: 10.1371/journal.pcbi.1007484

Auteurs

Lu Luo (L)

School of Psychological and Cognitive Sciences and Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, 100871, China.
School of Psychology, Beijing Sport University, Beijing, 100084, China.

Xiongfei Wang (X)

Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, 100093, China.
Beijing Key Laboratory of Epilepsy, Epilepsy Center, Sanbo Brain Hospital, Capital Medical University, Beijing, 100093, China.

Junshi Lu (J)

School of Psychological and Cognitive Sciences and Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, 100871, China.
IDG/McGovern Institute for Brain Research, Peking University, Beijing, 100871, China.

Guanpeng Chen (G)

School of Psychological and Cognitive Sciences and Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, 100871, China.
IDG/McGovern Institute for Brain Research, Peking University, Beijing, 100871, China.
Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, 100871, China.

Guoming Luan (G)

Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, 100093, China.
Beijing Key Laboratory of Epilepsy, Epilepsy Center, Sanbo Brain Hospital, Capital Medical University, Beijing, 100093, China.
Beijing Institute for Brain Disorders, Beijing, 100069, China.

Wu Li (W)

State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, 100875, China.

Qian Wang (Q)

School of Psychological and Cognitive Sciences and Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, 100871, China. wangqianpsy@pku.edu.cn.
IDG/McGovern Institute for Brain Research, Peking University, Beijing, 100871, China. wangqianpsy@pku.edu.cn.

Fang Fang (F)

School of Psychological and Cognitive Sciences and Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, 100871, China. ffang@pku.edu.cn.
IDG/McGovern Institute for Brain Research, Peking University, Beijing, 100871, China. ffang@pku.edu.cn.
Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, 100871, China. ffang@pku.edu.cn.

Classifications MeSH