Novel Antimicrobial Peptide from the Hepatopancreas of the Red King Crab.
antimicrobial peptides
hepatopancreas
red king crab
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
26 Oct 2023
26 Oct 2023
Historique:
received:
28
09
2023
revised:
17
10
2023
accepted:
23
10
2023
medline:
15
11
2023
pubmed:
14
11
2023
entrez:
14
11
2023
Statut:
epublish
Résumé
Crustaceans have successfully adapted to survive in their natural habitat, rich in microorganisms, due to the presence of antimicrobial peptides (AMPs) in their organism. They achieve this adaptation despite lacking the highly specific adaptive immune system found in vertebrates. One valuable source of AMPs is the hepatopancreas, a waste product from crab fishery and its processing. Applying zymographic and spectrophotometric techniques, we discovered a small peptide (approximately 5 kDa) within a low molecular weight protein fraction extracted from the acetone powder of the red king crab hepatopancreas. This peptide hydrolyzes both
Identifiants
pubmed: 37958589
pii: ijms242115607
doi: 10.3390/ijms242115607
pmc: PMC10649287
pii:
doi:
Substances chimiques
Antimicrobial Peptides
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : RSF
ID : 23-24-00278
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