Archaeal GPN-loop GTPases involve a lock-switch-rock mechanism for GTP hydrolysis.
GPN-loop
GTPase
RNA polymerase II
allostery
sulfolobus
Journal
mBio
ISSN: 2150-7511
Titre abrégé: mBio
Pays: United States
ID NLM: 101519231
Informations de publication
Date de publication:
14 Nov 2023
14 Nov 2023
Historique:
medline:
14
11
2023
pubmed:
14
11
2023
entrez:
14
11
2023
Statut:
aheadofprint
Résumé
GPN-loop GTPases have been found to be crucial for eukaryotic RNA polymerase II assembly and nuclear trafficking. Despite their ubiquitous occurrence in eukaryotes and archaea, the mechanism by which these GTPases mediate their function is unknown. Our study on an archaeal representative from
Identifiants
pubmed: 37962382
doi: 10.1128/mbio.00859-23
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM