Microglia in Central Control of Metabolism.

Humans Microglia / metabolism Obesity Hypothalamus / metabolism Energy Metabolism / physiology Homeostasis / physiology
diet-induced obesity glial hypothalamus metabolism

Journal

Physiology (Bethesda, Md.)
ISSN: 1548-9221
Titre abrégé: Physiology (Bethesda)
Pays: United States
ID NLM: 101208185

Informations de publication

Date de publication:
01 Jan 2024
Historique:
medline: 5 12 2023
pubmed: 14 11 2023
entrez: 14 11 2023
Statut: ppublish

Résumé

Beyond their role as brain immune cells, microglia act as metabolic sensors in response to changes in nutrient availability, thus playing a role in energy homeostasis. This review highlights the evidence and challenges of studying the role of microglia in metabolism regulation.

Identifiants

DOI: 10.1152/physiol.00021.2023 PMID: 37962895
pubmed: 37962895
doi: 10.1152/physiol.00021.2023
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

0

Subventions

Organisme : HHS | NIH | NIDDK | Division of Diabetes, Endocrinology, and Metabolic Diseases (DEM)
ID : DK130321, DK131717, DK136079

Auteurs

Jung Dae Kim (JD)

Institute of Human Nutrition, Columbia University Irving Medical Center, New York, New York, United States.

Francesca Copperi (F)

Institute of Human Nutrition, Columbia University Irving Medical Center, New York, New York, United States.

Sabrina Diano (S)

Institute of Human Nutrition, Columbia University Irving Medical Center, New York, New York, United States.
Department of Molecular Pharmacology and Therapeutics, Columbia University Irving Medical Center, New York, New York, United States.
Department of Physiology and Cellular Biophysics, Columbia University Irving Medical Center, New York, New York, United States.
ORCID: 0000-0002-7921-2617

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Microglia in Central Control of Metabolism.
questionsmedicales.fr › Cellules › Névroglie › Microglie › Microglia in Central Control of Metabolism.
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Obésité › Microglia in Central Control of Metabolism.
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Prosencéphale › Diencéphale › Hypothalamus › Microglia in Central Control of Metabolism.
questionsmedicales.fr › Métabolisme › Métabolisme énergétique › Microglia in Central Control of Metabolism.
questionsmedicales.fr › Phénomènes physiologiques › Homéostasie › Microglia in Central Control of Metabolism.