People with obesity exhibit losses in muscle proteostasis that are partly improved by exercise training.
biosynthetic labelling
deuterium oxide
fractional synthesis rate
heat shock proteins
heavy water
muscle protein synthesis
protein turnover
proteomics
skeletal muscle
ubiquitin proteasome system
Journal
Proteomics
ISSN: 1615-9861
Titre abrégé: Proteomics
Pays: Germany
ID NLM: 101092707
Informations de publication
Date de publication:
14 Nov 2023
14 Nov 2023
Historique:
received:
18
10
2023
accepted:
03
11
2023
medline:
15
11
2023
pubmed:
15
11
2023
entrez:
14
11
2023
Statut:
aheadofprint
Résumé
This pilot experiment examines if a loss in muscle proteostasis occurs in people with obesity and whether endurance exercise positively influences either the abundance profile or turnover rate of proteins in this population. Men with (n = 3) or without (n = 4) obesity were recruited and underwent a 14-d measurement protocol of daily deuterium oxide (D
Identifiants
pubmed: 37963832
doi: 10.1002/pmic.202300395
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2300395Subventions
Organisme : Royal Thai Government
Informations de copyright
© 2023 The Authors. Proteomics published by Wiley-VCH GmbH.
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