Domestic Parasitic Infections in Patients with Asthma and Eosinophilia in Germany - Three Cases with Learnings in the Era of Anti- IL5 Treatments.
anti-IL5 treatment
asthma
biologic
eosinophilia
parasitic infections
Journal
Journal of asthma and allergy
ISSN: 1178-6965
Titre abrégé: J Asthma Allergy
Pays: New Zealand
ID NLM: 101543450
Informations de publication
Date de publication:
2023
2023
Historique:
received:
05
07
2023
accepted:
18
10
2023
medline:
15
11
2023
pubmed:
15
11
2023
entrez:
15
11
2023
Statut:
epublish
Résumé
Eosinophilic inflammation is a hallmark of asthma, and blood eosinophilia has been established as a biomarker for phenotyping asthma and predicting the response to anti-IL5 treatments. Although parasitic infections are rare in European adults, they remain an important differential diagnosis for blood eosinophilia. We present three patients with both domestic parasitic infections and asthma to raise awareness of the potential challenge of eosinophilia and to provide experience in the management of parasitic infections in the setting of planned or ongoing anti-IL5 treatment. One, a patient from Croatia with moderate asthma but severe blood eosinophilia had an underlying
Identifiants
pubmed: 37965273
doi: 10.2147/JAA.S428607
pii: 428607
pmc: PMC10642391
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1229-1232Informations de copyright
© 2023 Barnikel et al.
Déclaration de conflit d'intérêts
KM received speaker fees from AstraZeneca, GSK, Novartis, and Sanofi, all outside of the submitted work.
Références
Clin Infect Dis. 2001 Oct 1;33(7):1040-7
pubmed: 11528578
PLoS Negl Trop Dis. 2013 Jul 11;7(7):e2288
pubmed: 23875033
J Asthma Allergy. 2019 Dec 11;12:415-420
pubmed: 31849501
BMC Pulm Med. 2023 Mar 22;23(1):96
pubmed: 36949398
PLoS Negl Trop Dis. 2022 Jul 20;16(7):e0010561
pubmed: 35857754
Eur Respir J. 2023 Jan 12;61(1):
pubmed: 35953100
Clin Microbiol Infect. 2015 Jun;21(6):543-52
pubmed: 25887711