Langerhans cell histiocytosis: current advances in molecular pathogenesis.
BRAFV600E
MAP2K1
dendritic cells
langerhans cell histiocytosis
monocytes
oncogene
senescence
Journal
Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960
Informations de publication
Date de publication:
2023
2023
Historique:
received:
09
08
2023
accepted:
16
10
2023
medline:
15
11
2023
pubmed:
15
11
2023
entrez:
15
11
2023
Statut:
epublish
Résumé
Langerhans cell histiocytosis (LCH) is a rare and clinically heterogeneous hematological disease characterized by the accumulation of mononuclear phagocytes in various tissues and organs. LCH is often characterized by activating mutations of the mitogen-activated protein kinase (MAPK) pathway with
Identifiants
pubmed: 37965340
doi: 10.3389/fimmu.2023.1275085
pmc: PMC10642229
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1275085Informations de copyright
Copyright © 2023 Sconocchia, Foßelteder, Sconocchia and Reinisch.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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