The wonders of stem cells therapeutic application towards chronic obstructive pulmonary disease.

Cell therapy Chronic obstructive pulmonary disease Regenerative medicine Stem cell Translational medicine

Journal

Pulmonary pharmacology & therapeutics
ISSN: 1522-9629
Titre abrégé: Pulm Pharmacol Ther
Pays: England
ID NLM: 9715279

Informations de publication

Date de publication:
Dec 2023
Historique:
received: 23 09 2023
revised: 01 10 2023
accepted: 09 11 2023
pubmed: 16 11 2023
medline: 16 11 2023
entrez: 15 11 2023
Statut: ppublish

Résumé

Chronic obstructive pulmonary disease (COPD) is a respiratory condition characterized by its heterogeneous nature, progressive course, and significant impact on individuals' quality of life. It is a prevalent global health issue affecting a substantial number of individuals and can pose life-threatening complications if left unmanaged. The development and course of COPD can be influenced by a range of risk factors, including genetic predisposition and environmental exposures. Nevertheless, as researchers adopt a more comprehensive and expansive viewpoint of therapeutic techniques, the associated obstacles become more apparent. Indeed, a definitive medication for COPD that reliably leads to symptom alleviation has not yet been discovered. Therefore, the limitations of conventional therapy methods prompted researchers to focus on the advancement of novel procedures, potentially leading to significant outcomes. In contemporary times, the field of regenerative medicine and cell therapy has presented unprecedented opportunities for the exploration of innovative treatments for COPD, owing to the distinctive attributes exhibited by stem cells. Hence, it is imperative to provide due consideration to preclinical investigations and notable characteristics of stem cells as they serve as a means to comprehensively comprehend the fundamental mechanisms of COPD and uncover novel therapeutic strategies with enhanced efficacy for patients.

Identifiants

pubmed: 37967760
pii: S1094-5539(23)00081-0
doi: 10.1016/j.pupt.2023.102269
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

102269

Informations de copyright

Copyright © 2023. Published by Elsevier Ltd.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Akram Tayanloo-Beik (A)

Cell Therapy and Regenerative Medicine Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: a.tayanloo@gmail.com.

Shayesteh Kokabi Hamidpour (S)

Iranian Cancer Control Center (MACSA), Tehran, Iran. Electronic address: sh.k.hamidpour@gmail.com.

Mohaddese Chaharbor (M)

Cell Therapy and Regenerative Medicine Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: mohaddesechaharbor@yahoo.com.

Mostafa Rezaei-Tavirani (M)

Proteomics Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: Tavirany@yahoo.com.

Rasta Arjmand (R)

Cell Therapy and Regenerative Medicine Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: rastaarjmand52@gmail.com.

Hossein Adibi (H)

Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: adibi@tums.ac.ir.

Hamid Ojagh (H)

Student Research Committee of Nursing, Faculty of Nursing, Aja University of Medical Sciences, Tehran, Iran. Electronic address: Hamid.ojagh31@gmail.com.

Bagher Larijani (B)

Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: emrc@tums.ac.ir.

Babak Arjmand (B)

Cell Therapy and Regenerative Medicine Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: barjmand@sina.tums.ac.ir.

Classifications MeSH