Illuminating protein space with a programmable generative model.


Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
Nov 2023
Historique:
received: 20 12 2022
accepted: 06 10 2023
medline: 1 12 2023
pubmed: 16 11 2023
entrez: 15 11 2023
Statut: ppublish

Résumé

Three billion years of evolution has produced a tremendous diversity of protein molecules

Identifiants

pubmed: 37968394
doi: 10.1038/s41586-023-06728-8
pii: 10.1038/s41586-023-06728-8
pmc: PMC10686827
doi:

Substances chimiques

Proteins 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1070-1078

Informations de copyright

© 2023. The Author(s).

Références

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Auteurs

John B Ingraham (JB)

Generate Biomedicines, Somerville, MA, USA.

Max Baranov (M)

Generate Biomedicines, Somerville, MA, USA.

Zak Costello (Z)

Generate Biomedicines, Somerville, MA, USA.

Karl W Barber (KW)

Generate Biomedicines, Somerville, MA, USA.

Wujie Wang (W)

Generate Biomedicines, Somerville, MA, USA.

Ahmed Ismail (A)

Generate Biomedicines, Somerville, MA, USA.

Vincent Frappier (V)

Generate Biomedicines, Somerville, MA, USA.

Dana M Lord (DM)

Generate Biomedicines, Somerville, MA, USA.

Christopher Ng-Thow-Hing (C)

Generate Biomedicines, Somerville, MA, USA.

Erik R Van Vlack (ER)

Generate Biomedicines, Somerville, MA, USA.

Shan Tie (S)

Generate Biomedicines, Somerville, MA, USA.

Vincent Xue (V)

Generate Biomedicines, Somerville, MA, USA.

Sarah C Cowles (SC)

Generate Biomedicines, Somerville, MA, USA.

Alan Leung (A)

Generate Biomedicines, Somerville, MA, USA.

João V Rodrigues (JV)

Generate Biomedicines, Somerville, MA, USA.

Claudio L Morales-Perez (CL)

Generate Biomedicines, Somerville, MA, USA.

Alex M Ayoub (AM)

Generate Biomedicines, Somerville, MA, USA.

Robin Green (R)

Generate Biomedicines, Somerville, MA, USA.

Katherine Puentes (K)

Generate Biomedicines, Somerville, MA, USA.

Frank Oplinger (F)

Generate Biomedicines, Somerville, MA, USA.

Nishant V Panwar (NV)

Generate Biomedicines, Somerville, MA, USA.

Fritz Obermeyer (F)

Generate Biomedicines, Somerville, MA, USA.

Adam R Root (AR)

Generate Biomedicines, Somerville, MA, USA.

Andrew L Beam (AL)

Generate Biomedicines, Somerville, MA, USA.

Frank J Poelwijk (FJ)

Generate Biomedicines, Somerville, MA, USA.

Gevorg Grigoryan (G)

Generate Biomedicines, Somerville, MA, USA. ggrigoryan@generatebiomedicines.com.

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Classifications MeSH