The optimal frozen embryo transfer strategy for the recurrent implantation failure patient without blastocyst freezing: thawing day 3 embryos and culturing to day 5 blastocysts.
Blastocyst
Day 3 embryo
Frozen–thawed embryo transfer
In vitro embryo culture
Repeated implantation failure
Journal
Zygote (Cambridge, England)
ISSN: 1469-8730
Titre abrégé: Zygote
Pays: England
ID NLM: 9309124
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
medline:
7
12
2023
pubmed:
16
11
2023
entrez:
16
11
2023
Statut:
ppublish
Résumé
This study aimed to investigate the optimal frozen embryo transfer (FET) strategy for recurrent implantation failure (RIF) patients with three consecutive failed cleaved embryo implantations and no blastocyst preservation. This retrospective analysis was divided into three groups based on the FET strategy: thawed day 3 embryo transfer (D3 FET group); and extended culture of frozen-thawed day 3 embryos to day 5 blastocysts transfer (D3-D5 FET group); thawed blastocyst transfer (D5 FET group). Transplant cycle data were compared between the three groups. In total, 43.8% of vitrified-thawed cleavage embryos developed into blastocysts. Analysis of the three transplantation strategies showed that, compared with the D3 FET group, D3-D5 had a significantly better hCG-positivity rate and live-birth rate (
Identifiants
pubmed: 37969109
pii: S0967199423000503
doi: 10.1017/S0967199423000503
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM