Crucial role of corticotropin-releasing hormone, corticotropin-releasing hormone -binding protein, mir-200c, and mir-181a in preterm delivery: A case-control study.
mir-181a
CRH
CRH-BP
Preterm labor.
mir-200c
Journal
International journal of reproductive biomedicine
ISSN: 2476-4108
Titre abrégé: Int J Reprod Biomed
Pays: Iran
ID NLM: 101679102
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
received:
03
04
2023
revised:
11
06
2023
accepted:
19
06
2023
medline:
16
11
2023
pubmed:
16
11
2023
entrez:
16
11
2023
Statut:
epublish
Résumé
Preterm birth before 37 The present study aimed to investigate the expression of mir-200c, mir-181a, CRH, and CRH-BP in women with a history of preterm birth. In this case-control study, the gene expression level of mir-200c, mir-181a, CRH, and CRH-BP in placental tissue samples obtained from 48 women with a history of preterm labor was assessed in the Mojibian hospital of Yazd, Iran, from January to March 2023. Differences between The outcomes indicated that the expression of CRH increased with going on to the regular parturition time (p In conclusion, the expressions of mir-200c, mir-181a, CRH, and CRH-BP were dissimilar in different weeks of gestation. It could be proposed to use mir-200c, mir-181a, CRH, and CRH-BP as biomarkers to weigh the exact delivery time, which could minimize the side effects of preterm labor for the mother and fetus.
Sections du résumé
Background
UNASSIGNED
Preterm birth before 37
Objective
UNASSIGNED
The present study aimed to investigate the expression of mir-200c, mir-181a, CRH, and CRH-BP in women with a history of preterm birth.
Materials and Methods
UNASSIGNED
In this case-control study, the gene expression level of mir-200c, mir-181a, CRH, and CRH-BP in placental tissue samples obtained from 48 women with a history of preterm labor was assessed in the Mojibian hospital of Yazd, Iran, from January to March 2023. Differences between
Results
UNASSIGNED
The outcomes indicated that the expression of CRH increased with going on to the regular parturition time (p
Conclusion
UNASSIGNED
In conclusion, the expressions of mir-200c, mir-181a, CRH, and CRH-BP were dissimilar in different weeks of gestation. It could be proposed to use mir-200c, mir-181a, CRH, and CRH-BP as biomarkers to weigh the exact delivery time, which could minimize the side effects of preterm labor for the mother and fetus.
Identifiants
pubmed: 37969569
doi: 10.18502/ijrm.v21i9.14398
pmc: PMC10643681
doi:
Types de publication
Journal Article
Langues
eng
Pagination
715-722Informations de copyright
Copyright © 2023 Mohiti Ardakani et al.
Déclaration de conflit d'intérêts
The authors declare that there is no conflict of interest.
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