Urine Quantification Following Furosemide for Severe Acute Kidney Injury Prediction in Critically Ill Children.
acute kidney injury
critically ill
furosemide
pediatrics
urine flow rate
Journal
Journal of pediatric intensive care
ISSN: 2146-4618
Titre abrégé: J Pediatr Intensive Care
Pays: Germany
ID NLM: 101592756
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
received:
14
04
2021
accepted:
12
06
2021
medline:
29
7
2021
pubmed:
29
7
2021
entrez:
16
11
2023
Statut:
epublish
Résumé
A standardized, quantified assessment of furosemide responsiveness predicts acute kidney injury (AKI) in children after cardiac surgery and AKI progression in critically ill adults. The purpose of this study was to determine if response to furosemide is predictive of severe AKI in critically ill children outside of cardiac surgery. We performed a multicenter retrospective study of critically ill children. Quantification of furosemide response was based on urine flow rate (normalized for weight) measurement 0 to 6 hours after the dose. The primary outcome was presence of creatinine defined severe AKI (Kidney Disease Improving Global Outcomes stage 2 or greater) within 7 days of furosemide administration. Secondary outcomes included mortality, duration of mechanical ventilation and length of stay. A total of 110 patients were analyzed. Severe AKI occurred in 20% (
Identifiants
pubmed: 37970140
doi: 10.1055/s-0041-1732447
pii: 2100049
pmc: PMC10631834
doi:
Types de publication
Journal Article
Langues
eng
Pagination
289-295Informations de copyright
Thieme. All rights reserved.
Déclaration de conflit d'intérêts
Conflict of interest None declared.
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