Can physicians and schools mitigate social inequalities in human papillomavirus vaccine awareness, uptake and vaccination intention among adolescents? A cross-sectional study, France, 2021 to 2022.
Humans
Adolescent
Cross-Sectional Studies
Human Papillomavirus Viruses
Papillomavirus Vaccines
Intention
Papillomavirus Infections
/ prevention & control
Vaccination
Schools
Physicians
Socioeconomic Factors
Surveys and Questionnaires
Patient Acceptance of Health Care
France
Health Knowledge, Attitudes, Practice
France
HPV vaccination
acceptance
awareness
general practitioner
school-based initiatives
social inequalities
uptake
Journal
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
ISSN: 1560-7917
Titre abrégé: Euro Surveill
Pays: Sweden
ID NLM: 100887452
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
medline:
20
11
2023
pubmed:
17
11
2023
entrez:
16
11
2023
Statut:
ppublish
Résumé
BackgroundIn France, human papillomavirus (HPV) vaccination coverage varies across socioeconomic levels.AimWe aimed at assessing HPV vaccine awareness, uptake and vaccination intention among adolescents in France.MethodsIn a cluster-randomised study, 13-15-year-old students in 61 French middle schools completed a web-based questionnaire. We used multivariable logistic regression to evaluate determinants of HPV vaccine awareness, self-reported uptake and vaccination intention among unvaccinated students and interaction terms to explore effects of visits to family physician and remembering school lessons on vaccination. The French deprivation index of school municipalities served as proxy for socioeconomic levels.ResultsAmong 6,992 participants, awareness was significantly associated with parental education (odds ratio (OR) = 0.82; 95% confidence interval (CI): 0.71-0.95), language spoken at home (OR = 0.59; 95% CI: 0.52-0.66) and deprivation level (OR = 0.57; 95% CI: 0.44-0.71), regardless of physician visit or school lessons. Vaccine uptake was associated with parental education without a recent physician visit (OR = 0.31; 95% CI: 0.16-0.59, vs OR = 0.64; 95% CI: 0.52-0.78 with a visit, interaction p = 0.045). Vaccination intention among unvaccinated was associated with deprivation level (moderate-low vs low) among students not remembering school lessons on vaccination (OR = 0.17; 95% CI: 0.05-0.62, vs OR = 0.93; 95% CI: 0.51-1.67 remembering school lessons, interaction p = 0.022). Parental education was associated with vaccination intention among students reporting a physician visit (OR = 0.41; 95% CI: 0.26-0.64 vs OR = 1.05; 95% CI: 0.50-2.20 without a visit, interaction p = 0.034).ConclusionOur results suggest that healthcare and school could promote vaccination and mitigate social inequalities in HPV vaccination coverage.
Identifiants
pubmed: 37971661
doi: 10.2807/1560-7917.ES.2023.28.46.2300166
pmc: PMC10655205
doi:
Substances chimiques
Papillomavirus Vaccines
0
Types de publication
Randomized Controlled Trial
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Références
Vaccine. 2016 Feb 3;34(6):762-8
pubmed: 26752063
J Prim Care Community Health. 2017 Oct;8(4):349-362
pubmed: 29161946
J Community Health. 2017 Apr;42(2):400-412
pubmed: 27734247
Vaccine. 2015 Sep 22;33(39):5188-95
pubmed: 26254978
Expert Rev Vaccines. 2018 Apr;17(4):311-321
pubmed: 29569498
BMC Public Health. 2009 Jan 22;9:33
pubmed: 19161613
Hum Vaccin Immunother. 2019;15(7-8):1615-1627
pubmed: 30633623
Sante Publique. 2020 Jun 18;Vol. 32(1):29-41
pubmed: 32706224
Public Health Rev. 2020 May 14;41:10
pubmed: 32435520
PLoS One. 2020 Oct 22;15(10):e0234693
pubmed: 33091021
Vaccine. 2021 Jun 29;39(29):3916-3925
pubmed: 34088507
N Engl J Med. 2023 May 11;388(19):1790-1798
pubmed: 37163625
Hum Vaccin Immunother. 2021 Nov 2;17(11):4470-4486
pubmed: 34473589
Hum Vaccin Immunother. 2018 Jul 3;14(7):1566-1572
pubmed: 29303677
Hum Vaccin Immunother. 2016 Jun 2;12(6):1454-68
pubmed: 26838681
BMJ Open. 2022 Mar 24;12(3):e057943
pubmed: 35332045
Asian Pac J Cancer Prev. 2021 Feb 01;22(2):349-357
pubmed: 33639647
Vaccine X. 2019 Aug 05;3:100037
pubmed: 31463471
Soc Sci Med. 2013 Apr;82:115-25
pubmed: 23337830
BMC Public Health. 2013 Jul 09;13:640
pubmed: 23837819
Vaccines (Basel). 2021 Jun 05;9(6):
pubmed: 34198885
Hum Vaccin Immunother. 2019;15(7-8):1752-1759
pubmed: 30735440
Hum Vaccin Immunother. 2019;15(7-8):1465-1475
pubmed: 30779682
Vaccine. 2020 Feb 5;38(6):1315-1331
pubmed: 31836255