Total Synthesis of Taxol Enabled by Intermolecular Radical Coupling and Pd-Catalyzed Cyclization.

Paclitaxel / chemistry Cyclization Palladium Ethers, Cyclic Stereoisomerism

Journal

Journal of the American Chemical Society
ISSN: 1520-5126
Titre abrégé: J Am Chem Soc
Pays: United States
ID NLM: 7503056

Informations de publication

Date de publication:
29 Nov 2023
Historique:
medline: 30 11 2023
pubmed: 17 11 2023
entrez: 16 11 2023
Statut: ppublish

Résumé

Taxol (

Identifiants

DOI: 10.1021/jacs.3c10658 PMID: 37972241
pubmed: 37972241
doi: 10.1021/jacs.3c10658
doi:

Substances chimiques

Paclitaxel P88XT4IS4D
oxetane I279Q16FU6
Palladium 5TWQ1V240M
Ethers, Cyclic 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

25894-25902

Auteurs

Takahiro Watanabe (T)

Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo113-0033, Japan.

Kyohei Oga (K)

Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo113-0033, Japan.

Hiroaki Matoba (H)

Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo113-0033, Japan.

Masanori Nagatomo (M)

Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo113-0033, Japan.
ORCID: 0000-0001-9204-194X

Masayuki Inoue (M)

Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo113-0033, Japan.
ORCID: 0000-0003-3274-551X

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Classifications MeSH

questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Terpènes › Diterpènes › Taxoïdes › Paclitaxel › Total Synthesis of Taxol Enabled by...
questionsmedicales.fr › Métabolisme › Cyclisation › Total Synthesis of Taxol Enabled by...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux lourds › Palladium › Total Synthesis of Taxol Enabled by...
questionsmedicales.fr › Composés polycycliques › Composés macrocycliques › Éthers cycliques › Total Synthesis of Taxol Enabled by...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes de chimie organique › Isomérie › Stéréoisomérie › Total Synthesis of Taxol Enabled by...