Protocol for dissecting cascade computational components in neural networks of a visual system.
Bioinformatics
Computer sciences
Neuroscience
Journal
STAR protocols
ISSN: 2666-1667
Titre abrégé: STAR Protoc
Pays: United States
ID NLM: 101769501
Informations de publication
Date de publication:
16 Nov 2023
16 Nov 2023
Historique:
received:
21
06
2023
revised:
26
08
2023
accepted:
30
10
2023
medline:
17
11
2023
pubmed:
17
11
2023
entrez:
17
11
2023
Statut:
aheadofprint
Résumé
Finding the complete functional circuits of neurons is a challenging problem in brain research. Here, we present a protocol, based on visual stimuli and spikes, for obtaining the complete circuit of recorded neurons using spike-triggered nonnegative matrix factorization. We describe steps for data preprocessing, inferring the spatial receptive field of the subunits, and analyzing the module matrix. This approach identifies computational components of the feedforward network of retinal ganglion cells and dissects the network structure based on natural image stimuli. For complete details on the use and execution of this protocol, please refer to Jia et al. (2021).
Identifiants
pubmed: 37976152
pii: S2666-1667(23)00689-5
doi: 10.1016/j.xpro.2023.102722
pmc: PMC10692719
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
102722Informations de copyright
Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of interests The authors declare no competing interests.
Références
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