Nut Consumption and Fertility: a Systematic Review and Meta-Analysis.

diet female infertility fertility male infertility nuts sperm quality

Journal

Advances in nutrition (Bethesda, Md.)
ISSN: 2156-5376
Titre abrégé: Adv Nutr
Pays: United States
ID NLM: 101540874

Informations de publication

Date de publication:
17 Nov 2023
Historique:
received: 14 07 2023
revised: 18 09 2023
accepted: 13 11 2023
pubmed: 18 11 2023
medline: 18 11 2023
entrez: 17 11 2023
Statut: aheadofprint

Résumé

The high concentration of omega-3 polyunsaturated fats, dietary fibers, vitamins, minerals, and polyphenols found in nuts suggest their regular consumption may be a simple strategy for improving reproductive health. This systematic review and meta-analysis aimed to present up-to-date evidence regarding the association between nut intake and fertility outcomes in males and females. Ovid MEDLINE, Embase, CINAHL, and Scopus were searched from inception to 30 June 2023. Eligible articles were interventional or observational studies in human subjects of reproductive age (18-49 y) that assessed the effects (or association) of dietary nut consumption (for a minimum of 3 mo) on fertility-related outcomes. Random-effects meta-analyses were completed to produce a pooled effect estimate of nut consumption on sperm total motility, vitality, morphology, and concentration in healthy males. Four studies involving 875 participants (646 males, 229 females) were included in this review. Meta-analysis of 2 RCTs involving 223 healthy males indicated consumption of ≥ 60g nuts/d increased sperm motility, vitality, and morphology in comparison to controls but had no effect on sperm concentration. Nonrandomized studies reported no association between dietary nut intake and conventional sperm parameters in males, embryo implantation, clinical pregnancy or live birth in males and females undergoing ART. Our meta-analysis shows that including at least 2 servings of nuts daily as part of a Western-style diet in healthy males improves sperm parameters, which are predictors of male fertility. Due to their nutritional profile, nuts were found to have potential to promote successful reproductive outcomes. This trial was registered at PROSPERO (CRD42020204586).

Identifiants

DOI: 10.1016/j.advnut.2023.100153 PMID: 37977328 PMC: PMC10704322
pubmed: 37977328
pii: S2161-8313(23)01437-0
doi: 10.1016/j.advnut.2023.100153
pmc: PMC10704322
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

100153

Informations de copyright

Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.

Références

Nat Rev Urol. 2017 Aug;14(8):470-485
pubmed: 28508879
PLoS Med. 2012;9(12):e1001356
pubmed: 23271957
Stat Methods Med Res. 2020 Sep;29(9):2520-2537
pubmed: 32292115
Reprod Biol Endocrinol. 2015 Apr 26;13:37
pubmed: 25928197
World J Mens Health. 2023 Oct;41(4):809-847
pubmed: 37118965
Int J Vitam Nutr Res. 2013;83(5):263-70
pubmed: 25305221
Andrology. 2023 May 25;:
pubmed: 37226894
PLoS One. 2014 Jul 30;9(7):e103376
pubmed: 25076495
F S Rep. 2020 Nov 18;2(1):109-117
pubmed: 34223281
Reprod Biol Endocrinol. 2019 Sep 2;17(1):73
pubmed: 31477128
Adv Nutr. 2021 Jun 1;12(3):777-792
pubmed: 33330927
Inflammation. 2018 Aug;41(4):1182-1193
pubmed: 29663102
Andrology. 2015 May;3(3):450-61
pubmed: 25951427
Heliyon. 2021 Nov 09;7(11):e08338
pubmed: 34820542
Fertil Steril. 2015 Nov;104(5):1104-10
pubmed: 26364838
Clin Nutr. 2009 Feb;28(1):39-45
pubmed: 19010571
Fertil Steril. 2020 Sep;114(3):610-617
pubmed: 32712021
Curr Atheroscler Rep. 2010 Nov;12(6):397-406
pubmed: 20820955
Adv Nutr. 2023 Jan;14(1):77-98
pubmed: 36811596
Nutrients. 2015 Nov 05;7(11):9139-53
pubmed: 26556369
Arch Androl. 2001 May-Jun;46(3):169-75
pubmed: 11339641
Int J Mol Med. 2019 Jun;43(6):2523-2531
pubmed: 31017264
J Am Coll Cardiol. 2020 Nov 10;76(19):2282-2284
pubmed: 33153588
Br J Nutr. 2021 Mar 14;125(5):508-520
pubmed: 32713355
Mymensingh Med J. 2015 Oct;24(4):704-9
pubmed: 26620007
Fertil Steril. 2010 Nov;94(6):2096-101
pubmed: 20189169
Eur J Nutr. 2020 Oct;59(7):2841-2856
pubmed: 32372265
Am J Obstet Gynecol. 2022 Aug;227(2):246.e1-246.e11
pubmed: 35364062
Curr Atheroscler Rep. 2018 Aug 9;20(10):48
pubmed: 30094487
Andrology. 2019 Mar;7(2):156-162
pubmed: 30663272
Nutr Rev. 2019 Oct 1;77(10):691-709
pubmed: 31361320
Andrologia. 2011 Feb;43(1):38-47
pubmed: 21219381
Hormones (Athens). 2023 Jun;22(2):165-197
pubmed: 36725796
Curr Opin Obstet Gynecol. 2022 Aug 1;34(4):184-189
pubmed: 35895959
Fertil Steril. 2023 Aug;120(2):333-357
pubmed: 37061157
Am J Obstet Gynecol. 2019 Jun;220(6):567.e1-567.e18
pubmed: 30742825
Foods. 2023 Feb 23;12(5):
pubmed: 36900459
Hum Reprod. 2007 Jul;22(7):1871-7
pubmed: 17478459
Food Funct. 2022 Oct 3;13(19):9904-9917
pubmed: 36053223
J Nutr Metab. 2012;2012:539426
pubmed: 22570770
Food Funct. 2023 Jul 3;14(13):5962-5976
pubmed: 37306209
Food Res Int. 2017 Oct;100(Pt 2):9-18
pubmed: 28888463
Syst Biol Reprod Med. 2016 Dec;62(6):387-395
pubmed: 27792396
J Clin Endocrinol Metab. 2018 Dec 1;103(12):4501-4510
pubmed: 30124893
Am J Clin Nutr. 2007 Jan;85(1):231-7
pubmed: 17209201
BMJ. 2016 Oct 12;355:i4919
pubmed: 27733354
Fertil Steril. 2014 Oct;102(4):998-1005.e8
pubmed: 25190048
Expert Opin Drug Metab Toxicol. 2017 Jan;13(1):51-58
pubmed: 27590039
Fertil Steril. 2009 Jun;91(6):2281-94
pubmed: 19481642
Nutrients. 2019 Jan 08;11(1):
pubmed: 30626111
Nutrients. 2020 Jan 10;12(1):
pubmed: 31936720
Postepy Hig Med Dosw (Online). 2017 May 9;71(0):359-366
pubmed: 28513460
BMJ. 2019 Aug 28;366:l4898
pubmed: 31462531
Hum Reprod. 2018 Mar 1;33(3):494-502
pubmed: 29390148
Front Nutr. 2022 Oct 31;9:1011850
pubmed: 36386927
Biol Reprod. 2021 May 7;104(5):976-994
pubmed: 33598687
Hum Reprod Update. 2017 Jul 1;23(4):371-389
pubmed: 28333357
Clin Trials. 2005;2(2):141-51
pubmed: 16279136
Adv Nutr. 2022 Jun 1;13(3):857-874
pubmed: 35293975
Hum Reprod. 2017 Jan;32(1):215-222
pubmed: 27994040
Antioxidants (Basel). 2023 Mar 30;12(4):
pubmed: 37107211
Adv Nutr. 2021 Dec 1;12(6):2372-2386
pubmed: 34139003
J Nepal Health Res Counc. 2019 Apr 28;17(1):85-89
pubmed: 31110383
Antioxidants (Basel). 2019 Aug 02;8(8):
pubmed: 31382427
Reprod Biol Endocrinol. 2005 Jul 14;3:28
pubmed: 16018814
Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):2848-2853
pubmed: 28223487
Theriogenology. 2017 Mar 1;90:289-300
pubmed: 28166982
Afr J Reprod Health. 2020 Jun;24(2):85-95
pubmed: 34077094
Iran Biomed J. 2012;16(3):162-8
pubmed: 23023218
Reprod Biol Endocrinol. 2004 Mar 23;2:12
pubmed: 15038829
Obes Rev. 2021 Nov;22(11):e13330
pubmed: 34494363
Reprod Biol Endocrinol. 2022 Feb 19;20(1):33
pubmed: 35183196
Am J Clin Nutr. 2018 Nov 1;108(5):953-962
pubmed: 30475967
Arch Gynecol Obstet. 2013 Jul;288(1):191-9
pubmed: 23543240
Nutrients. 2017 Dec 02;9(12):
pubmed: 29207471
Biol Reprod. 2012 Oct 25;87(4):101
pubmed: 22895856
Circulation. 2008 Feb 12;117(6):754-61
pubmed: 18212291
Andrologia. 2018 Dec;50(11):e13126
pubmed: 30569652
Semin Reprod Med. 2013 Jul;31(4):293-300
pubmed: 23775385
Int J Mol Sci. 2020 Oct 21;21(20):
pubmed: 33096823
J Int Med Res. 2020 Jun;48(6):300060520932403
pubmed: 32600086
Am J Clin Nutr. 2016 Sep;104(3):722-8
pubmed: 27465378
Int J Environ Res Public Health. 2019 Dec 06;16(24):
pubmed: 31817639
J Clin Epidemiol. 2009 Oct;62(10):1006-12
pubmed: 19631508

Auteurs

Barbara R Cardoso (BR)

Department of Nutrition, Dietetics and Food, Monash University, Victoria, Australia; Victorian Heart Institute, Monash University, Clayton, Victoria, Australia. Electronic address: barbara.cardoso@monash.edu.

Izabella Fratezzi (I)

Department of Nutrition, Dietetics and Food, Monash University, Victoria, Australia.

Nicole J Kellow (NJ)

Department of Nutrition, Dietetics and Food, Monash University, Victoria, Australia; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, Victoria, Australia. Electronic address: nicole.kellow@monash.edu.

Classifications MeSH