Features of Interferon Status and Methods of Its Correction in the Treatment of Patients with Atypical Chronic Active Herpesvirus Infections.
herpesvirus infections
immunocompromised patients
interferon system
Journal
Bulletin of experimental biology and medicine
ISSN: 1573-8221
Titre abrégé: Bull Exp Biol Med
Pays: United States
ID NLM: 0372557
Informations de publication
Date de publication:
Oct 2023
Oct 2023
Historique:
received:
04
04
2023
medline:
1
12
2023
pubmed:
18
11
2023
entrez:
18
11
2023
Statut:
ppublish
Résumé
It is known that the imbalance of the IFN system is the cornerstone of the immunopathogenesis of atypical chronic active herpesvirus infections and is often associated not only with congenital, genetically determined defects, but also with acquired system dysregulation at different levels: receptor, molecular, at the level of a nuclear transducer of signal transmission. Based on the studied features of immunopathogenesis and the revealed disturbances in the antiviral immune defense system and the IFN system in patients with atypical chronic herpes viral infections, an integration program for correcting IFN status was developed, its clinical and immunological effectiveness was evaluated. Improved effectiveness of complex rehabilitation of immunocompromised patients with atypical chronic active herpes viral infections was demonstrated.
Identifiants
pubmed: 37979025
doi: 10.1007/s10517-023-05948-2
pii: 10.1007/s10517-023-05948-2
doi:
Substances chimiques
Interferons
9008-11-1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
791-793Informations de copyright
© 2023. Springer Science+Business Media, LLC, part of Springer Nature.
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