A review on methods for extracting and quantifying microplastic in biological tissues.

Literature about the occurrence of microplastic in biological tissues has increased over the last few years. This review aims to synthesis the evidence on the preparation of biological tissues, chemical identification of microplastic and accumulation in tissues. Several microplastic's extraction approaches from biological tissues emerged (i.e., alkaline, acids, oxidizing and enzymatic). However, criteria used for the selection of the extraction method have yet to be clarified. Similarly, analytical methodologies for chemical identification often does not align with the size of particles. Furthermore, sizes of microplastics found in biological tissues are likely to be biologically implausible, due to the size of the biological barriers. From this review, it emerged that further assessment are required to determine whether microplastic particles were truly internalized, were in the vasculature serving these organs, or were an artefact of the methodological process. The importance of a standardisation of quality control/quality assurance emerged. Findings arose from this review could have a broad implication, and could be used as a basis for further investigations, to reduce artifact results and clearly assess the fate of microplastics in biological tissues.

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Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.