Engineered bacteria titrate hydrogen sulfide and induce concentration-dependent effects on the host in a gut microphysiological system.

CP: Microbiology bioengineering gut metabolome gut microbiome gut microphysiological system gut on a chip host-microbe interactions hydrogen sulfide inflammatory bowel disease metabolic engineering synthetic biology

Journal

Cell reports
ISSN: 2211-1247
Titre abrégé: Cell Rep
Pays: United States
ID NLM: 101573691

Informations de publication

Date de publication:
18 Nov 2023
Historique:
received: 06 06 2023
revised: 05 10 2023
accepted: 06 11 2023
medline: 19 11 2023
pubmed: 19 11 2023
entrez: 19 11 2023
Statut: aheadofprint

Résumé

Hydrogen sulfide (H

Identifiants

DOI: 10.1016/j.celrep.2023.113481 PMID: 37980564
pubmed: 37980564
pii: S2211-1247(23)01493-6
doi: 10.1016/j.celrep.2023.113481
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

113481

Commentaires et corrections

Type : UpdateOf

Informations de copyright

Copyright © 2023 The Author(s). Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare no competing interests.

Auteurs

Justin A Hayes (JA)

Department of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.

Anna W Lunger (AW)

Department of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.

Aayushi S Sharma (AS)

Department of Mechanical and Industrial Engineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA; Department of Bioengineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.

Matthew T Fernez (MT)

Department of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.

Rebecca L Carrier (RL)

Department of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA; Department of Bioengineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA; Department of Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.

Abigail N Koppes (AN)

Department of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA; Department of Bioengineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.

Ryan Koppes (R)

Department of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA. Electronic address: r.koppes@northeastern.edu.

Benjamin M Woolston (BM)

Department of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA. Electronic address: b.woolston@northeastern.edu.

Classifications MeSH