Unusual location of subungual melanoma surgically managed successfully: A rare case report from Syria.

Acral lentiginous melanoma (ALM) Case report Dermatological malignancy Hutchinson's sign Nail lesion Subungual melanoma (SUM)

Journal

International journal of surgery case reports
ISSN: 2210-2612
Titre abrégé: Int J Surg Case Rep
Pays: Netherlands
ID NLM: 101529872

Informations de publication

Date de publication:
Dec 2023
Historique:
received: 19 09 2023
revised: 08 11 2023
accepted: 11 11 2023
medline: 20 11 2023
pubmed: 20 11 2023
entrez: 19 11 2023
Statut: ppublish

Résumé

Acral lentiginous melanoma (ALM), the least common subtype of cutaneous melanoma, poses challenges in early detection, resulting in low survival rates. Subungual melanoma (SUM), a rare form of ALM originating from the nail matrix, is less common on the hands than on the feet, accounting in the hands for only 0.3 % of all cutaneous melanomas. This makes the case of hand subungual melanoma that we are presenting very rare and significant. A 64-year-old woman presented with an asymptomatic subungual lesion on her left fifth finger. The lesion, ranging in color from brown to black, did not cause bleeding and exhibited a clear nail plate rupture. An incisional biopsy confirmed the diagnosis of subungual melanoma. The patient underwent a proximal interphalangeal (PIP) joint amputation and remains in good health. Regular CT scans and clinical examination have shown no recurrence. Subungual melanoma, a rare subtype of acral lentiginous melanoma, comprises less than 1 % of all melanomas. While the Hallux and thumb are commonly affected, our case involved the little finger which is the rarest site of hand subungual melanoma. Occurrence ages are between 50 and 70. The Hutchinson sign, nail fold pigmentation, indicates poor prognosis in advanced stages, which was positive in our case. Recommended management is amputation at the level of the most distal unaffected joint. Our aim is to raise healthcare professionals' awareness of early recognition and management of subungual melanoma. Early detection and treatment reduce metastasis risk and improve survival rates.

Identifiants

pubmed: 37980775
pii: S2210-2612(23)01191-4
doi: 10.1016/j.ijscr.2023.109062
pmc: PMC10694301
pii:
doi:

Types de publication

Case Reports

Langues

eng

Pagination

109062

Informations de copyright

Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest All authors declared no conflict of interest.

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Auteurs

Muhammad Anas Kudsi (MA)

Faculty of Medicine, Aleppo University, Aleppo, Syria. Electronic address: kudsianas@gmail.com.

Mohammed Sami Kudsi (MS)

Department of General Surgery, Aleppo University Hospital, Aleppo University, Aleppo, Syria.

Ayesha Ghazy (A)

Faculty of Medicine, Aleppo University, Aleppo, Syria.

Rama Alyousfi (R)

Department of Pathology, Aleppo University Hospital, Aleppo University, Aleppo, Syria.

M Noor Khouja (MN)

Department of Plastic Surgery, Aleppo University Hospital, Aleppo University, Aleppo, Syria.

Aladdin Etr (A)

Department of Plastic Surgery, Aleppo University Hospital, Aleppo University, Aleppo, Syria.

Classifications MeSH