Histopathology and indicators of borderline ovarian tumours with microinvasion in bitches.
gynaecological diseases
implantation metastases
prognostic significance
veterinary pathology
Journal
Veterinarni medicina
ISSN: 0375-8427
Titre abrégé: Vet Med (Praha)
Pays: Czech Republic
ID NLM: 0063417
Informations de publication
Date de publication:
Apr 2023
Apr 2023
Historique:
received:
17
11
2022
accepted:
08
03
2023
medline:
20
11
2023
pubmed:
20
11
2023
entrez:
20
11
2023
Statut:
epublish
Résumé
The authors present two cases of borderline ovarian tumours with microinvasion in bitches with variable clinical significance. The first case documents a four-year-old female Weimaraner diagnosed with a tumour on the right ovary during a veterinary check-up, using ultrasound (USG) examination, which was then surgically removed. Histological examination revealed a clear cell borderline tumour of the ovary with microinvasion. The second case is represented by a necropsy sample from a 52-month-old female German Shepherd who died a day before the planned hysterectomy due to undertreated pyometra. During necropsy, a developed bilateral ovarian tumour was found. An additional histological examination revealed a serous borderline tumour with microinvasion of both ovaries. This paper discusses the histopathological and clinical aspects involved in the prognosis of borderline ovarian tumours in bitches. This concerns the possibility of a change for a more aggressive behaviour of these tumours and their immunohistochemical profile, then the risk of implant metastases and, finally, the time point of diagnosis, intervention, and therapy. Even histologically verified well-differentiated forms of borderline ovarian tumours with microinvasion in bitches can show the variable clinical significance and, therefore, in similar cases, only a good or only a bad prognosis of the disease should not be expected.
Identifiants
pubmed: 37982087
doi: 10.17221/103/2022-VETMED
pii: 122103
pmc: PMC10581509
doi:
Types de publication
Case Reports
Langues
eng
Pagination
175-183Informations de copyright
Copyright: © 2023 Makovicky et al.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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