Exploring the Acceptability of Behavioral Swallowing Interventions for Head and Neck Cancer Patients During Radiotherapy: A Qualitative Study of Patients' Experience.

Head and neck cancer Intervention acceptability Qualitative research Radiotherapy Swallowing Theoretical framework of acceptability

Journal

Dysphagia
ISSN: 1432-0460
Titre abrégé: Dysphagia
Pays: United States
ID NLM: 8610856

Informations de publication

Date de publication:
22 Nov 2023
Historique:
received: 25 06 2023
accepted: 29 10 2023
medline: 22 11 2023
pubmed: 22 11 2023
entrez: 22 11 2023
Statut: aheadofprint

Résumé

The PRO-ACTIVE randomized clinical trial offers 3 swallowing therapies to Head and Neck Cancer (HNC) patients during radiotherapy namely: reactive, proactive low- ("EAT-RT" only), and high-intensity ("EAT-RT + exercises"). Understanding the perceived acceptability of these interventions is important to inform eventual implementation into clinical practice. This study explored patients' perspectives using qualitative methodology. At 2 Canadian PRO-ACTIVE trial sites, 24 trial participants were recruited for individual semi-structured interviews, representing each of the 3 trial arms. Data collection and thematic analysis were guided by the Theoretical Framework of Acceptability (TFA). Member checking was conducted through follow-up focus groups. Seven themes were derived reflecting the TFA constructs. Overall, regardless of trial arm, patients reported a positive experience with therapy. Patients identified benefits of EAT-RT therapy, reporting that it provided meaningful feedback on diet progress and supported goal setting for oral intake. Patients who received proactive therapies valued the opportunity to set expectations early, build mealtime routine iteratively over time, and have an extended engagement with the SLP. Regardless of trial arm, patients agreed proactive therapy aligned with what they think is best and that therapy intensity should accommodate individual needs. This study identified the value to HNC patients of receiving swallowing interventions during RT and setting realistic expectations around swallowing. Compared to reactive care, proactive therapies were perceived helpful in consolidating habits early, establishing realistic expectations around swallowing and building an extended rapport with the SLP. These findings will inform the implementation of proactive versus reactive swallowing therapies in clinical practice.

Identifiants

pubmed: 37991659
doi: 10.1007/s00455-023-10640-8
pii: 10.1007/s00455-023-10640-8
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Peterborough K. M. Hunter Charitable Foundation
ID : 2022-2023 Peterborough K. M. Hunter Charitable Foundation Graduate Award
Organisme : Canada Excellence Research Chairs, Government of Canada
ID : Canada Research Chair (Tier II) in Swallowing Disorders

Informations de copyright

© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Références

McEwen S, et al. “I didn’t actually know there was such a thing as rehab”: survivor, family, and clinician perceptions of rehabilitation following treatment for head and neck cancer. Support Care Cancer. 2016;24(4):1449–53.
pubmed: 26576966 doi: 10.1007/s00520-015-3021-1
Baijens LWJ, et al. European white paper: oropharyngeal dysphagia in head and neck cancer. Eur Arch Otorhinolaryngol. 2021;278(2):577–616.
pubmed: 33341909 doi: 10.1007/s00405-020-06507-5
Govender R, et al. Swallowing interventions for the treatment of dysphagia after head and neck cancer: a systematic review of behavioural strategies used to promote patient adherence to swallowing exercises. BMC Cancer. 2017;17(1):43.
pubmed: 28068939 pmcid: 5223405 doi: 10.1186/s12885-016-2990-x
Hutcheson KA, et al. Two-year prevalence of dysphagia and related outcomes in head and neck cancer survivors: an updated SEER-Medicare analysis. Head Neck. 2019;41(2):479–87.
pubmed: 30536748 doi: 10.1002/hed.25412
Cristofaro MG, et al. The health risks of dysphagia for patients with head and neck cancer: a multicentre prospective observational study. J Transl Med. 2021;19(1):472.
pubmed: 34809654 pmcid: 8607588 doi: 10.1186/s12967-021-03144-2
Greco E, et al. Presence and duration of feeding tube in a 5-year cohort of patients with head and neck cancer treated with curative intensity-modulated radiation therapy. Head Neck. 2021;43(5):1610–20.
pubmed: 33580567 doi: 10.1002/hed.26638
Hutcheson KA, et al. Eat and exercise during radiotherapy or chemoradiotherapy for pharyngeal cancers: use it or lose it. JAMA Otolaryngol Head Neck Surg. 2013;139(11):1127–34.
pubmed: 24051544 pmcid: 3969836 doi: 10.1001/jamaoto.2013.4715
Hunter KU, et al. Aspiration pneumonia after chemo-intensity-modulated radiation therapy of oropharyngeal carcinoma and its clinical and dysphagia-related predictors. Head Neck. 2014;36(1):120–5.
pubmed: 23729173 doi: 10.1002/hed.23275
Xu B, et al. Aspiration pneumonia after concurrent chemoradiotherapy for head and neck cancer. Cancer. 2015;121(8):1303–11.
pubmed: 25537836 doi: 10.1002/cncr.29207
Szczesniak MM, et al. Persistent dysphagia after head and neck radiotherapy: a common and under-reported complication with significant effect on non-cancer-related mortality. Clin Oncol. 2014;26(11):697–703.
doi: 10.1016/j.clon.2014.08.009
Bressan V, et al. The life experience of nutrition impact symptoms during treatment for head and neck cancer patients: a systematic review and meta-synthesis. Support Care Cancer. 2017;25(5):1699–712.
pubmed: 28204992 doi: 10.1007/s00520-017-3618-7
Qualizza M, et al. Listening to the voice of patients with head and neck cancer: a systematic review and meta-synthesis. Eur J Cancer Care. 2019;28(3): e12939.
doi: 10.1111/ecc.12939
Greco E, et al. Dysphagia treatment for patients with head and neck cancer undergoing radiation therapy: a meta-analysis review. Int J Radiat Oncol Biol Phys. 2018;101(2):421–44.
pubmed: 29726363 doi: 10.1016/j.ijrobp.2018.01.097
Martino R, McCulloch T. Therapeutic intervention in oropharyngeal dysphagia. Nat Rev Gastroenterol Hepatol. 2016;13(11):665–79.
pubmed: 27625188 doi: 10.1038/nrgastro.2016.127
Mirabile A, et al. Pain management in head and neck cancer patients undergoing chemo-radiotherapy: clinical practical recommendations. Crit Rev Oncol Hematol. 2016;99:100–6.
pubmed: 26712589 doi: 10.1016/j.critrevonc.2015.11.010
Gulliford SL, et al. Dosimetric explanations of fatigue in head and neck radiotherapy: an analysis from the PARSPORT phase III trial. Radiother Oncol. 2012;104(2):205–12.
pubmed: 22883107 doi: 10.1016/j.radonc.2012.07.005
Xiao C, et al. Symptom clusters in patients with head and neck cancer receiving concurrent chemoradiotherapy. Oral Oncol. 2013;49(4):360–6.
pubmed: 23168337 doi: 10.1016/j.oraloncology.2012.10.004
Trotti A, et al. Mucositis incidence, severity and associated outcomes in patients with head and neck cancer receiving radiotherapy with or without chemotherapy: a systematic literature review. Radiother Oncol. 2003;66(3):253–62.
pubmed: 12742264 doi: 10.1016/S0167-8140(02)00404-8
Jensen SB, et al. A systematic review of salivary gland hypofunction and xerostomia induced by cancer therapies: prevalence, severity and impact on quality of life. Support Care Cancer. 2010;18(8):1039–60.
pubmed: 20237805 doi: 10.1007/s00520-010-0827-8
van den Berg MG, et al. A prospective study on weight loss and energy intake in patients with head and neck cancer, during diagnosis, treatment and revalidation. Clin Nutr. 2006;25(5):765–72.
pubmed: 16698130 doi: 10.1016/j.clnu.2005.12.007
Vissink A, et al. Oral sequelae of head and neck radiotherapy. Crit Rev Oral Biol Med. 2003;14(3):199–212.
pubmed: 12799323 doi: 10.1177/154411130301400305
Kearney A, Cavanagh PW. Acute and long-term effects of chemoradiation therapy in head and neck cancer. In: Doyle PC, editor. Clinical care and rehabilitation in head and neck cancer. New York: Springer; 2019.
Muzumder S, et al. Burden of acute toxicities in head-and-neck radiation therapy: a single-institutional experience. South Asian J Cancer. 2019;8(2):120–3.
pubmed: 31069194 pmcid: 6498722 doi: 10.4103/sajc.sajc_264_17
Meyer F, et al. Predictors of severe acute and late toxicities in patients with localized head-and-neck cancer treated with radiation therapy. Int J Radiat Oncol Biol Phys. 2012;82(4):1454–62.
pubmed: 21640495 doi: 10.1016/j.ijrobp.2011.04.022
Wells M, King E. Patient adherence to swallowing exercises in head and neck cancer. Curr Opin Otolaryngol Head Neck Surg. 2017;25(3):175–81.
pubmed: 28266944 pmcid: 5462098 doi: 10.1097/MOO.0000000000000356
Sekhon M, Cartwright M, Francis JJ. Acceptability of healthcare interventions: an overview of reviews and development of a theoretical framework. BMC Health Serv Res. 2017;17(1):88.
pubmed: 28126032 pmcid: 5267473 doi: 10.1186/s12913-017-2031-8
Patterson JM, et al. Feasibility and acceptability of combining cognitive behavioural therapy techniques with swallowing therapy in head and neck cancer dysphagia. BMC Cancer. 2018;18(1):1.
pubmed: 29291726 pmcid: 5748941 doi: 10.1186/s12885-017-3892-2
Govender R, et al. SIP SMART: a parallel group randomised feasibility trial of a tailored pre-treatment swallowing intervention package compared with usual care for patients with head and neck cancer. BMC Cancer. 2020;20(1):360.
pubmed: 32349693 pmcid: 7191731 doi: 10.1186/s12885-020-06877-3
O’Cathain A, et al. Getting added value from using qualitative research with randomized controlled trials: a qualitative interview study. Trials. 2014;15:215.
pubmed: 24913438 pmcid: 4059032 doi: 10.1186/1745-6215-15-215
Johnson RB, Schoonenboom J. Adding qualitative and mixed methods research to health intervention studies: interacting with differences. Qual Health Res. 2016;26(5):587–602.
pubmed: 26657970 doi: 10.1177/1049732315617479
Dawson C, Adams J, Fenlon D. The experiences of people who receive swallow therapy after surgical treatment of head and neck cancer. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019;128(5):456–63.
pubmed: 31227448 doi: 10.1016/j.oooo.2019.03.012
Checklin M, et al. Patients’ perspectives on what makes a better care experience while undergoing treatment for oropharyngeal dysphagia secondary to head and neck cancer. Dysphagia. 2020;35(4):702–16.
pubmed: 31748827 doi: 10.1007/s00455-019-10077-y
Govender R, et al. Helping patients with head and neck cancer understand dysphagia: exploring the use of video-animation. Am J Speech Lang Pathol. 2019;28(2):697–705.
pubmed: 31136243 pmcid: 6802865 doi: 10.1044/2018_AJSLP-18-0184
Messing BP, et al. Establishing a multidisciplinary head and neck clinical pathway: an implementation evaluation and audit of dysphagia-related services and outcomes. Dysphagia. 2019;34(1):89–104.
pubmed: 29922848 doi: 10.1007/s00455-018-9917-4
Caelli K, Ray L, Mill J. “Clear as mud”: toward greater clarity in generic qualitative research. Int J Qual Methods. 2003;2(2):1–24.
doi: 10.1177/160940690300200201
Martino R, et al. The PRO-ACTIVE trial protocol: a randomized study comparing the effectiveness of prophylactic swallow intervention for patients receiving radiotherapy for head and neck cancer. BMC Cancer. 2021;21(1):1100.
pubmed: 34645411 pmcid: 8513207 doi: 10.1186/s12885-021-08826-0
Hutcheson KA, et al. Eat All Through Radiation Therapy (EAT-RT): structured therapy model to facilitate continued oral intake through head and neck radiotherapy-user acceptance and content validation. Head Neck. 2020;42(9):2390–6.
pubmed: 32445231 doi: 10.1002/hed.26250
Manduchi B, Fitch M, Ringash J, Howell D, Hutcheson K, Martino R. The acceptability of behavioural swallowing interventions for head and neck cancer patients during radiotherapy: a qualitative study exploring experiences of clinical trial speech-language pathologists. Dysphagia. 2023. https://doi.org/10.1007/s00455-023-10625-7 .
Braun V, Clarke V. Using thematic analysis in psychology. Qual Res Psychol. 2006;3(2):77–101.
doi: 10.1191/1478088706qp063oa
Lincoln YS, Guba EG. Naturalistic inquiry. Beverly Hills: Sage Publications; 1985.
doi: 10.1016/0147-1767(85)90062-8
Tong A, Sainsbury P, Craig J. Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups. Int J Qual Health Care. 2007;19(6):349–57.
pubmed: 17872937 doi: 10.1093/intqhc/mzm042
Senchak JJ, Fang CY, Bauman JR. Interventions to improve quality of life (QOL) and/or mood in patients with head and neck cancer (HNC): a review of the evidence. Cancers Head Neck. 2019;4:2.
pubmed: 31210980 pmcid: 6560898 doi: 10.1186/s41199-019-0041-4
Melchers LJ, et al. Exercise adherence in patients with trismus due to head and neck oncology: a qualitative study into the use of the therabite. Int J Oral Maxillofac Surg. 2009;38(9):947–54.
pubmed: 19414238 doi: 10.1016/j.ijom.2009.04.003
Wall LR, et al. Adherence to a prophylactic swallowing therapy program during (chemo) radiotherapy: impact of service-delivery model and patient factors. Dysphagia. 2017;32(2):279–92.
pubmed: 27844152 doi: 10.1007/s00455-016-9757-z
Cnossen IC, et al. Multimodal guided self-help exercise program to prevent speech, swallowing, and shoulder problems among head and neck cancer patients: a feasibility study. J Med Internet Res. 2014;16(3): e74.
pubmed: 24610383 pmcid: 3961811 doi: 10.2196/jmir.2990
Govender R, et al. Patient experiences of swallowing exercises after head and neck cancer: a qualitative study examining barriers and facilitators using behaviour change theory. Dysphagia. 2017;32(4):559–69.
pubmed: 28424898 pmcid: 5515965 doi: 10.1007/s00455-017-9799-x
Hajdu SF, et al. Adherence to preventive swallowing exercises for head and neck cancer patients undergoing (chemo)radiotherapy treatment. Acta Oncol. 2019;58(5):658–64.
pubmed: 30698049 doi: 10.1080/0284186X.2018.1563715
Baudelet M, et al., Increasing adherence to prophylactic swallowing exercises during head and neck radiotherapy: the multicenter, randomized controlled PRESTO-trial. Dysphagia 2022;1–10.
Brockbank S, et al. Pretreatment information on dysphagia: exploring the views of head and neck cancer patients. J Pain Symptom Manag. 2015;49(1):89–97.
doi: 10.1016/j.jpainsymman.2014.04.014
Daun JT, et al. A qualitative study of patient and healthcare provider perspectives on building multiphasic exercise prehabilitation into the surgical care pathway for head and neck cancer. Curr Oncol. 2022;29(8):5942–54.
pubmed: 36005207 pmcid: 9406549 doi: 10.3390/curroncol29080469
Wade DT. Goal setting in rehabilitation: an overview of what, why and how. Clin Rehabil. 2009;23(4):291–5.
pubmed: 19293289 doi: 10.1177/0269215509103551
Rose A, Rosewilliam S, Soundy A. Shared decision making within goal setting in rehabilitation settings: a systematic review. Patient Educ Couns. 2017;100(1):65–75.
pubmed: 27486052 doi: 10.1016/j.pec.2016.07.030
Gardner T, et al. Combined education and patient-led goal setting intervention reduced chronic low back pain disability and intensity at 12 months: a randomised controlled trial. Br J Sports Med. 2019;53(22):1424–31.
pubmed: 30808666 doi: 10.1136/bjsports-2018-100080
Levack WM, et al. Goal setting and strategies to enhance goal pursuit for adults with acquired disability participating in rehabilitation. Cochrane Database Syst Rev. 2015;2015(7):CD009727.
pubmed: 26189709 pmcid: 8941379
Turner-Stokes L, et al. Patient engagement and satisfaction with goal planning: Impact on outcome from rehabilitation. Int J Ther Rehabil. 2015;22(5):210–6.
doi: 10.12968/ijtr.2015.22.5.210
Preede L, et al. Rehabilitation goals and effects of goal achievement on outcome following an adapted physical activity-based rehabilitation intervention. Patient Prefer Adherence. 2021;15:1545–55.
pubmed: 34276210 pmcid: 8277449 doi: 10.2147/PPA.S311966
Glazier SR, et al. Taking the next steps in goal ascertainment: a prospective study of patient, team, and family perspectives using a comprehensive standardized menu in a geriatric assessment and treatment unit. J Am Geriatr Soc. 2004;52(2):284–9.
pubmed: 14728642 doi: 10.1111/j.1532-5415.2004.52072.x
Rice DB, et al. Patient-centered goal setting in a hospital-based outpatient stroke rehabilitation center. PM R. 2017;9(9):856–65.
pubmed: 28082180 doi: 10.1016/j.pmrj.2016.12.004
Hausman DM. Preference, value, choice, and welfare. Cambridge: Cambridge University Press; 2012. p. 153.
Sidani S, et al. Relationships between personal beliefs and treatment acceptability, and preferences for behavioral treatments. Behav Res Ther. 2009;47(10):823–9.
pubmed: 19604500 pmcid: 2742570 doi: 10.1016/j.brat.2009.06.009
Elwyn G, et al. Implementing shared decision making in the NHS. BMJ. 2010;341: c5146.
pubmed: 20947577 doi: 10.1136/bmj.c5146
Hibbard JH, et al. Do increases in patient activation result in improved self-management behaviors? Health Serv Res. 2007;42(4):1443–63.
pubmed: 17610432 pmcid: 1955271 doi: 10.1111/j.1475-6773.2006.00669.x
Poon BY, Shortell SM, Rodriguez HP. Patient activation as a pathway to shared decision-making for adults with diabetes or cardiovascular disease. J Gen Intern Med. 2020;35(3):732–42.
pubmed: 31646455 doi: 10.1007/s11606-019-05351-6
Krist AH, et al. Engaging patients in decision-making and behavior change to promote prevention. Stud Health Technol Inform. 2017;240:284–302.
pubmed: 28972524 pmcid: 6996004
Lindhiem O, et al. Client preferences affect treatment satisfaction, completion, and clinical outcome: a meta-analysis. Clin Psychol Rev. 2014;34(6):506–17.
pubmed: 25189522 pmcid: 4176894 doi: 10.1016/j.cpr.2014.06.002
Hess EP, et al. Shared decision making in patients with low risk chest pain: prospective randomized pragmatic trial. BMJ. 2016;355: i6165.
pubmed: 27919865 pmcid: 5152707 doi: 10.1136/bmj.i6165
Oshima Lee E, Emanuel EJ. Shared decision making to improve care and reduce costs. N Engl J Med. 2013;368(1):6–8.
pubmed: 23281971 doi: 10.1056/NEJMp1209500
Joosten E, et al. Effect of shared decision-making on therapeutic alliance in addiction health care. Patient Prefer Adherence. 2008;2:277–85.
pubmed: 19920974 pmcid: 2770415 doi: 10.2147/PPA.S4149
Kaizer F, Spiridigliozzi AM, Hunt MR. Promoting shared decision-making in rehabilitation: development of a framework for situations when patients with Dysphagia refuse diet modification recommended by the treating team. Dysphagia. 2012;27(1):81–7.
pubmed: 21533793 doi: 10.1007/s00455-011-9341-5
Popay J, Rogers A, Williams G. Rationale and standards for the systematic review of qualitative literature in health services research. Qual Health Res. 1998;8(3):341–51.
pubmed: 10558335 doi: 10.1177/104973239800800305

Auteurs

Beatrice Manduchi (B)

Rehabilitation Sciences Institute, University of Toronto, Toronto, ON, Canada. beatrice.manduchi@mail.utoronto.ca.
Department of Speech-Language Pathology, University of Toronto, Toronto, ON, Canada. beatrice.manduchi@mail.utoronto.ca.
The Swallowing Lab, University of Toronto, Toronto, ON, Canada. beatrice.manduchi@mail.utoronto.ca.

Margaret I Fitch (MI)

Bloomberg Faculty of Nursing, University of Toronto, Toronto, ON, Canada.

Jolie G Ringash (JG)

Department of Radiation Oncology, Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Department of Otolaryngology- Head and Neck Surgery, University of Toronto, Toronto, ON, Canada.

Doris Howell (D)

Princess Margaret Cancer Centre, Toronto, ON, Canada.
Faculty of Nursing, University of Toronto, Toronto, ON, Canada.

Katherine A Hutcheson (KA)

Department of Head and Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Division of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Rosemary Martino (R)

Rehabilitation Sciences Institute, University of Toronto, Toronto, ON, Canada.
Department of Speech-Language Pathology, University of Toronto, Toronto, ON, Canada.
The Swallowing Lab, University of Toronto, Toronto, ON, Canada.
Department of Otolaryngology- Head and Neck Surgery, University of Toronto, Toronto, ON, Canada.
Krembil Research Institute, University Health Network, Toronto, ON, Canada.

Classifications MeSH