Elastomeric vitrimers from designer polyhydroxyalkanoates with recyclability and biodegradability.


Journal

Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440

Informations de publication

Date de publication:
24 11 2023
Historique:
medline: 27 11 2023
pubmed: 22 11 2023
entrez: 22 11 2023
Statut: ppublish

Résumé

Cross-linked elastomers are stretchable materials that typically are not recyclable or biodegradable. Medium-chain-length polyhydroxyalkanoates (mcl-PHAs) are soft and ductile, making these bio-based polymers good candidates for biodegradable elastomers. Elasticity is commonly imparted by a cross-linked network structure, and covalent adaptable networks have emerged as a solution to prepare recyclable thermosets via triggered rearrangement of dynamic covalent bonds. Here, we develop biodegradable and recyclable elastomers by chemically installing the covalent adaptable network within biologically produced mcl-PHAs. Specifically, an engineered strain of

Identifiants

pubmed: 37992173
doi: 10.1126/sciadv.adi1735
pmc: PMC10664982
doi:

Substances chimiques

Polyhydroxyalkanoates 0
Elastomers 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

eadi1735

Subventions

Organisme : National Renewable Energy Laboratory,
ID : DE-AC36-08GO28308
Organisme : National Renewable Energy Laboratory
ID : DE-AC36-08GO28308
Organisme : Alliance for Sustainable Energy LLC and with Argonne National Laboratory
ID : DE-AC02-06CH11357.
Organisme : US Department of Energy, Office of Science, Office of Basic Energy Sciences
ID : DE-AC02-76SF00515

Références

Adv Mater. 2017 Apr;29(14):
pubmed: 28221707
Macromol Rapid Commun. 2021 Feb;42(3):e2000475
pubmed: 33205556
Metab Eng. 2020 Nov;62:62-71
pubmed: 32828991
J Am Chem Soc. 2015 May 27;137(20):6492-5
pubmed: 25945818
Microb Biotechnol. 2020 Jan;13(1):290-298
pubmed: 31468725
Metab Eng. 2015 Mar;28:240-247
pubmed: 25617773
Biomacromolecules. 2019 Feb 11;20(2):645-652
pubmed: 30222322
Sci Robot. 2022 May 4;7(66):eabm6807
pubmed: 35584202
J Am Chem Soc. 2019 Oct 16;141(41):16181-16196
pubmed: 31525287
Mater Sci Eng C Mater Biol Appl. 2017 Nov 1;80:760-770
pubmed: 28866226
Biomacromolecules. 2004 Mar-Apr;5(2):480-5
pubmed: 15003009
J Magn Reson. 2003 Jun;162(2):479-86
pubmed: 12810033
Microb Ecol. 2017 Feb;73(2):353-367
pubmed: 27623963
Science. 2017 Apr 7;356(6333):62-65
pubmed: 28386008
Int J Biol Macromol. 1990 Apr;12(2):158-65
pubmed: 2078532
Metab Eng. 2011 Jan;13(1):11-7
pubmed: 20971206
Metab Eng. 2018 Jul;48:197-207
pubmed: 29885475
Nat Commun. 2021 Apr 15;12(1):2261
pubmed: 33859194
J Am Chem Soc. 2020 Dec 30;142(52):21852-21860
pubmed: 33332118
Adv Mater. 2019 Nov;31(48):e1904765
pubmed: 31538370
Chem Soc Rev. 2015 May 21;44(10):2865-79
pubmed: 25788317
Bioresour Technol. 2021 Dec;342:126008
pubmed: 34592618
Annu Rev Chem Biomol Eng. 2019 Jun 7;10:175-198
pubmed: 30883213
Metab Eng. 2023 Mar;76:193-203
pubmed: 36796578
Environ Microbiol. 2016 Feb;18(2):341-57
pubmed: 25556983
Metab Eng. 2020 Mar;58:82-93
pubmed: 31302223
Adv Mater. 2021 May;33(19):e2004413
pubmed: 33336520
Front Bioeng Biotechnol. 2022 Jan 05;9:817023
pubmed: 35071219
Metab Eng. 2012 Nov;14(6):705-13
pubmed: 23141473
ACS Macro Lett. 2015 Jul 21;4(7):673-678
pubmed: 35596485
Biomacromolecules. 2013 Sep 9;14(9):2963-72
pubmed: 23875914
Int J Biol Macromol. 1999 Jun-Jul;25(1-3):87-94
pubmed: 10416654
Metab Eng. 2020 May;59:119-130
pubmed: 32119929
Environ Sci Technol. 2018 Sep 18;52(18):10441-10452
pubmed: 30156110
ACS Appl Mater Interfaces. 2018 Jul 18;10(28):24224-24231
pubmed: 29943978
Int J Biol Macromol. 2001 Aug 20;29(2):73-82
pubmed: 11518578
Adv Mater. 2020 Sep;32(35):e1907138
pubmed: 32249983
Science. 2022 Oct 14;378(6616):207-211
pubmed: 36227984
Macromol Rapid Commun. 2012 Dec 13;33(23):2041-5
pubmed: 22961806
Biomacromolecules. 2019 Sep 9;20(9):3303-3312
pubmed: 31094501
Int J Biol Macromol. 2016 Feb;83:358-65
pubmed: 26616449
Appl Microbiol Biotechnol. 2023 Mar;107(5-6):1863-1874
pubmed: 36763117
Sci Robot. 2022 Feb 2;7(63):eabn8147
pubmed: 35108025
Adv Mater. 2021 Oct;33(41):e2102766
pubmed: 34322928
Adv Mater. 2022 Jun;34(25):e2105020
pubmed: 34757632
Metab Eng. 2021 Jul;66:167-178
pubmed: 33865980
Metab Eng. 2020 May;59:64-75
pubmed: 31931111

Auteurs

Robin M Cywar (RM)

Renewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, CO 80401, USA.
BOTTLE Consortium, Golden, CO 80401, USA.

Chen Ling (C)

Renewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, CO 80401, USA.
Agile BioFoundry, Golden, CO 80401, USA.

Ryan W Clarke (RW)

Renewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, CO 80401, USA.
BOTTLE Consortium, Golden, CO 80401, USA.
Department of Chemistry, Colorado State University, Fort Collins, CO 80523-1872, USA.

Dong Hyun Kim (DH)

Renewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, CO 80401, USA.
Agile BioFoundry, Golden, CO 80401, USA.

Colin M Kneucker (CM)

Renewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, CO 80401, USA.
Agile BioFoundry, Golden, CO 80401, USA.

Davinia Salvachúa (D)

Renewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, CO 80401, USA.
Agile BioFoundry, Golden, CO 80401, USA.

Bennett Addison (B)

Renewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, CO 80401, USA.

Sarah A Hesse (SA)

BOTTLE Consortium, Golden, CO 80401, USA.
Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA 94025, USA.

Christopher J Takacs (CJ)

BOTTLE Consortium, Golden, CO 80401, USA.
Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA 94025, USA.

Shu Xu (S)

Applied Materials Division, Argonne National Laboratory, Lemont, IL 60439, USA.
Northwestern Argonne Institute of Science and Engineering, 2205 Tech Drive, Suite 1160, Evanston, IL 60208, USA.

Meltem Urgun Demirtas (MU)

Applied Materials Division, Argonne National Laboratory, Lemont, IL 60439, USA.

Sean P Woodworth (SP)

Renewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, CO 80401, USA.
BOTTLE Consortium, Golden, CO 80401, USA.

Nicholas A Rorrer (NA)

Renewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, CO 80401, USA.
BOTTLE Consortium, Golden, CO 80401, USA.

Christopher W Johnson (CW)

Renewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, CO 80401, USA.
Agile BioFoundry, Golden, CO 80401, USA.

Christopher J Tassone (CJ)

BOTTLE Consortium, Golden, CO 80401, USA.
Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA 94025, USA.

Robert D Allen (RD)

Renewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, CO 80401, USA.
BOTTLE Consortium, Golden, CO 80401, USA.

Eugene Y-X Chen (EY)

Department of Chemistry, Colorado State University, Fort Collins, CO 80523-1872, USA.

Gregg T Beckham (GT)

Renewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, CO 80401, USA.
BOTTLE Consortium, Golden, CO 80401, USA.
Agile BioFoundry, Golden, CO 80401, USA.

Articles similaires

Humans Infusions, Intravenous Immune Checkpoint Inhibitors Infusion Pumps Elastomers

Emergent behaviors of buckling-driven elasto-active structures.

Yuchen Xi, Tom Marzin, Richard B Huang et al.
1.00
Elasticity Robotics Animals Movement
Humans Female Male Fracture Fixation, Intramedullary Child
Polyhydroxyalkanoates Carbon Saccharum Molasses Oryza

Classifications MeSH