Thyroid hormone receptor Thra and Thrb knockout differentially affects osteoblast biology and thyroid hormone responsiveness in vitro.
TRα1
TRβ1
Thra
Thrb
osteoblast-osteoclast coupling
osteoblastogenesis
thyroid hormone receptor
Journal
Journal of cellular biochemistry
ISSN: 1097-4644
Titre abrégé: J Cell Biochem
Pays: United States
ID NLM: 8205768
Informations de publication
Date de publication:
22 Nov 2023
22 Nov 2023
Historique:
revised:
30
10
2023
received:
27
07
2023
accepted:
06
11
2023
medline:
22
11
2023
pubmed:
22
11
2023
entrez:
22
11
2023
Statut:
aheadofprint
Résumé
Thyroid hormones (TH) are important modulators of bone remodeling and thus, thyroid diseases, in particular hyperthyroidism, are able to compromise bone quality and fracture resistance. TH actions on bone are mediated by the thyroid hormone receptors (TR) TRα1 and TRβ1, encoded by Thra and Thrb, respectively. Skeletal phenotypes of mice lacking Thra (Thra
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Deutsche Forschungsgemeinschaft
ID : LA 4945/1-1
Organisme : Medical Faculty of the Technische Universität Dresden
ID : MeDDrive-Start grant
Organisme : Fritz Thyssen Stiftung
ID : Az. 10.20.2.042MN
Organisme : Elsbeth-Bonhoff-Stiftung
Organisme : Graduate Academy, Technische Universität Dresden Germany
ID : PostDoc Starter Kit
Informations de copyright
© 2023 The Authors. Journal of Cellular Biochemistry published by Wiley Periodicals LLC.
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