case of autoimmune GFAP astrocytopathy with eosinophils in the cerebrospinal fluid.
Autoimmune encephalitis
Eosinophils
Glial fibrillary acidic protein astrocytopathy
Meningitis
Journal
Journal of neuroimmunology
ISSN: 1872-8421
Titre abrégé: J Neuroimmunol
Pays: Netherlands
ID NLM: 8109498
Informations de publication
Date de publication:
15 Dec 2023
15 Dec 2023
Historique:
received:
29
09
2023
revised:
10
11
2023
accepted:
14
11
2023
pubmed:
23
11
2023
medline:
23
11
2023
entrez:
22
11
2023
Statut:
ppublish
Résumé
Cerebrospinal fluid (CSF) eosinophilia is associated with a narrow differential, primarily including parasitic and fungal infections, neoplasm, and chemical meningitis. It has rarely been reported in neuroinflammatory conditions including as a finding of CSF cytology in two autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy cases. Here we describe a case of autoimmune GFAP astrocytopathy with classic clinical and radiographic features as well as presence of eosinophils in the CSF. This case highlights a potential association of eosinophils in the CSF with autoimmune GFAP astrocytopathy, which may suggest its inclusion in the differential diagnosis of eosinophilic meningitis, encephalitis, or myelitis.
Identifiants
pubmed: 37992587
pii: S0165-5728(23)00235-7
doi: 10.1016/j.jneuroim.2023.578249
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
578249Informations de copyright
Copyright © 2023. Published by Elsevier B.V.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors have no competing interests to disclose.