Motion direction is represented as a bimodal probability distribution in the human visual cortex.
Journal
Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555
Informations de publication
Date de publication:
22 Nov 2023
22 Nov 2023
Historique:
received:
11
11
2022
accepted:
03
11
2023
medline:
24
11
2023
pubmed:
23
11
2023
entrez:
22
11
2023
Statut:
epublish
Résumé
Humans infer motion direction from noisy sensory signals. We hypothesize that to make these inferences more precise, the visual system computes motion direction not only from velocity but also spatial orientation signals - a 'streak' created by moving objects. We implement this hypothesis in a Bayesian model, which quantifies knowledge with probability distributions, and test its predictions using psychophysics and fMRI. Using a probabilistic pattern-based analysis, we decode probability distributions of motion direction from trial-by-trial activity in the human visual cortex. Corroborating the predictions, the decoded distributions have a bimodal shape, with peaks that predict the direction and magnitude of behavioral errors. Interestingly, we observe similar bimodality in the distribution of the observers' behavioral responses across trials. Together, these results suggest that observers use spatial orientation signals when estimating motion direction. More broadly, our findings indicate that the cortical representation of low-level visual features, such as motion direction, can reflect a combination of several qualitatively distinct signals.
Identifiants
pubmed: 37993430
doi: 10.1038/s41467-023-43251-w
pii: 10.1038/s41467-023-43251-w
pmc: PMC10665457
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
7634Subventions
Organisme : EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council)
ID : 677601
Organisme : EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council)
ID : 677601
Informations de copyright
© 2023. The Author(s).
Références
Neuron. 2021 Nov 17;109(22):3699-3712.e6
pubmed: 34525327
J Neurosci. 2001 Jul 1;21(13):4809-21
pubmed: 11425908
Vis Neurosci. 2001 Jul-Aug;18(4):501-16
pubmed: 11829297
J Vis. 2005 Dec 16;5(10):878-87
pubmed: 16441191
J Vis. 2004 May 18;4(6):415-26
pubmed: 15330709
J Neurosci. 2017 May 17;37(20):5195-5203
pubmed: 28432137
J Illusion. 2022 Jan 10;3:
pubmed: 35111989
J Neurosci. 2014 Feb 12;34(7):2592-604
pubmed: 24523549
Cell Rep. 2021 Jan 12;34(2):108617
pubmed: 33440151
J Neurosci. 2014 Sep 10;34(37):12601-15
pubmed: 25209297
Vis Neurosci. 1996 Jan-Feb;13(1):87-100
pubmed: 8730992
Vision Res. 2003 Oct;43(23):2451-68
pubmed: 12972395
Neuroimage. 1999 Feb;9(2):195-207
pubmed: 9931269
Nat Neurosci. 2011 Jun 05;14(7):926-32
pubmed: 21642976
J Neurosci. 2002 Oct 1;22(19):8661-4
pubmed: 12351740
J Vis. 2011 Jun 23;11(7):17
pubmed: 21700953
Vision Res. 1976;16(2):187-91
pubmed: 1266060
Science. 1995 May 12;268(5212):889-93
pubmed: 7754376
Nature. 2003 Jun 26;423(6943):986-90
pubmed: 12827202
Curr Biol. 2006 Jun 6;16(11):1096-102
pubmed: 16753563
Percept Psychophys. 2007 Jan;69(1):48-55
pubmed: 17515215
Nat Neurosci. 2020 Jan;23(1):122-129
pubmed: 31873286
Vision Res. 1987;27(6):953-65
pubmed: 3660656
Neuropsychologia. 2012 Mar;50(4):514-21
pubmed: 21945806
Cereb Cortex. 2005 Aug;15(8):1207-21
pubmed: 15616136
Neuroimage. 2012 Jul 16;61(4):1402-18
pubmed: 22430496
Vision Res. 2003 Nov;43(24):2539-58
pubmed: 13129541
Psychol Methods. 2011 Dec;16(4):406-19
pubmed: 21787084
PLoS One. 2007 Sep 26;2(9):e943
pubmed: 17895984
Vision Res. 1997 Mar;37(5):553-63
pubmed: 9156199
Cereb Cortex. 1997 Mar;7(2):181-92
pubmed: 9087826
Nat Hum Behav. 2022 Feb;6(2):294-305
pubmed: 35058641
PLoS One. 2014 Mar 28;9(3):e93115
pubmed: 24682033
Neuron. 2018 Jan 17;97(2):462-474.e6
pubmed: 29290551
Nat Commun. 2023 Nov 22;14(1):7634
pubmed: 37993430
J Neurophysiol. 2013 Mar;109(5):1233-49
pubmed: 23197457
Nat Neurosci. 2015 Dec;18(12):1728-30
pubmed: 26502262
J Neurosci. 2000 Jul 15;20(14):RC86
pubmed: 10875941
Proc Biol Sci. 2012 Dec 05;280(1752):20122339
pubmed: 23222445
J Neurosci. 2002 Aug 15;22(16):7195-205
pubmed: 12177214
Nature. 1999 Jul 1;400(6739):65-9
pubmed: 10403249
Nat Neurosci. 2015 Oct;18(10):1509-17
pubmed: 26343249
Spat Vis. 1997;10(4):437-42
pubmed: 9176953
Proc Natl Acad Sci U S A. 1996 Mar 19;93(6):2382-6
pubmed: 8637882
Neuron. 2016 Aug 3;91(3):694-707
pubmed: 27497224
J Neurosci. 1996 Nov 1;16(21):6945-64
pubmed: 8824332
Neuroimage. 2002 Oct;17(2):825-41
pubmed: 12377157
J Neurophysiol. 1984 Dec;52(6):1106-30
pubmed: 6520628
Nat Neurosci. 2006 Nov;9(11):1421-31
pubmed: 17041595
Neuroimage. 2018 Oct 15;180(Pt A):78-87
pubmed: 28801251
Vision Res. 2007 Mar;47(6):828-33
pubmed: 17258262
J Neurosci. 2012 Sep 26;32(39):13363-79
pubmed: 23015427
J Physiol. 2007 Dec 1;585(Pt 2):383-400
pubmed: 17962332
Vision Res. 2011 Jul 1;51(13):1431-56
pubmed: 21324335
Neuroimage. 2010 Dec;53(4):1181-96
pubmed: 20637289
Spat Vis. 1997;10(4):433-6
pubmed: 9176952
Nature. 2009 May 7;459(7243):89-92
pubmed: 19270683
Neuroimage. 2014 Oct 15;100:564-79
pubmed: 24996120
J Opt Soc Am A Opt Image Sci Vis. 1998 Aug;15(8):2003-11
pubmed: 9691484
Neuroimage. 2012 Nov 15;63(3):1393-403
pubmed: 22922368
Curr Opin Neurobiol. 2016 Apr;37:126-132
pubmed: 26922005
J Vis. 2009 May 14;9(5):10.1-14
pubmed: 19757888