[Research progress on genetic variants of PDE4D and susceptibility to stroke in Chinese population].
Journal
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics
ISSN: 1003-9406
Titre abrégé: Zhonghua Yi Xue Yi Chuan Xue Za Zhi
Pays: China
ID NLM: 9425197
Informations de publication
Date de publication:
10 Dec 2023
10 Dec 2023
Historique:
medline:
24
11
2023
pubmed:
23
11
2023
entrez:
23
11
2023
Statut:
ppublish
Résumé
The pathogenesis of stroke is complex, with genetic risk factors as one of the main factors. The genetic variants of phosphodiesterase 4D (PDE4D) was significantly associated with the susceptibility to ischemic stroke (IS) in Caucasian population, but its association with the susceptibility to stroke in Chinese population is unclear. This article is intended to review the research on the association between PDE4D genetic variants and stroke susceptibility in Chinese population, aiming to further optimize the relevant research programs and provide reference for the prevention and treatment of stroke in China.
Identifiants
pubmed: 37994145
pii: 940640248
doi: 10.3760/cma.j.cn511374-20220810-00538
doi:
Substances chimiques
Cyclic Nucleotide Phosphodiesterases, Type 4
EC 3.1.4.17
PDE4D protein, human
EC 3.1.4.17
Types de publication
Review
English Abstract
Journal Article
Langues
chi
Sous-ensembles de citation
IM