Characterisation and prion transmission study in mice with genetic reduction of sporadic Creutzfeldt-Jakob disease risk gene Stx6.

Creutzfeldt-Jakob disease Incubation period Prion disease SNARE Syntaxin-6

Journal

Neurobiology of disease
ISSN: 1095-953X
Titre abrégé: Neurobiol Dis
Pays: United States
ID NLM: 9500169

Informations de publication

Date de publication:
22 Nov 2023
Historique:
received: 16 08 2023
revised: 20 11 2023
accepted: 20 11 2023
pubmed: 24 11 2023
medline: 24 11 2023
entrez: 23 11 2023
Statut: aheadofprint

Résumé

Sporadic Creutzfeldt-Jakob disease (sCJD), the most common human prion disease, is thought to occur when the cellular prion protein (PrP

Identifiants

DOI: 10.1016/j.nbd.2023.106363 PMID: 37996040
pubmed: 37996040
pii: S0969-9961(23)00379-0
doi: 10.1016/j.nbd.2023.106363
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

106363

Informations de copyright

Copyright © 2023 The Author(s). Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest J.C. is a director and shareholder of D-Gen Limited, an academic spin-out company in the field of prion diagnosis, decontamination and therapeutics. There are no other competing interests.

Auteurs

Emma Jones (E)

Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, UK.

Elizabeth Hill (E)

Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, UK.

Jacqueline Linehan (J)

Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, UK.

Tamsin Nazari (T)

Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, UK.

Adam Caulder (A)

Mary Lyon Centre at MRC Harwell, Harwell Campus, Oxfordshire OX11 0RD, UK.

Gemma F Codner (GF)

Mary Lyon Centre at MRC Harwell, Harwell Campus, Oxfordshire OX11 0RD, UK.

Marie Hutchison (M)

Mary Lyon Centre at MRC Harwell, Harwell Campus, Oxfordshire OX11 0RD, UK.

Matthew Mackenzie (M)

Mary Lyon Centre at MRC Harwell, Harwell Campus, Oxfordshire OX11 0RD, UK.

Michael Farmer (M)

Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, UK.

Thomas Coysh (T)

Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, UK.

Michael Wiggins De Oliveira (MW)

Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, UK.

Huda Al-Doujaily (H)

Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, UK.

Malin Sandberg (M)

Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, UK.

Emmanuelle Viré (E)

Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, UK.

Thomas J Cunningham (TJ)

Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, UK.

Emmanuel A Asante (EA)

Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, UK.

Sebastian Brandner (S)

Division of Neuropathology and Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.

John Collinge (J)

Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, UK.

Simon Mead (S)

Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, UK. Electronic address: s.mead@prion.ucl.ac.uk.

Classifications MeSH