Functionalized heteroatom-doped carbon dots for biomedical applications: A review.
Biosensing
Carbon dots
Multimodal imaging
Phosphorescence
Theranostics
Upconversion
Journal
Analytica chimica acta
ISSN: 1873-4324
Titre abrégé: Anal Chim Acta
Pays: Netherlands
ID NLM: 0370534
Informations de publication
Date de publication:
15 Dec 2023
15 Dec 2023
Historique:
received:
11
05
2023
revised:
18
09
2023
accepted:
04
10
2023
medline:
27
11
2023
pubmed:
24
11
2023
entrez:
23
11
2023
Statut:
ppublish
Résumé
Carbon nanoparticles (CDs) have recently drawn a great attention in (bio)chemical analysis, sensing and bioimaging owing to their photostability, water stability, minimal toxicity, biocompatibility and ease of surface functionalization. While the vast majority of CDs applications rely on exploiting their fluorescent properties, doping such nanomaterials with various elements has recently received increasing attention as an effective approach to modify their optoelectronic characteristics, introducing novel improved optical features such as phosphorescence, upconversion luminescence or multimodal imaging capabilities. This review article focuses in the recent advances on the synthesis of heteroatom-doped CDs, exhibiting distinctive features of high value for sensing and imaging, as well as various functionalization schemes developed for guided analyte labeling. Relevant applications in chemical sensing, bioimaging and disease therapy are here presented. A final section intends to provide an overview towards future developments of such emerging light-emitting nanomaterials in the design of future devices and strategies for (bio)analytical chemistry.
Identifiants
pubmed: 37996151
pii: S0003-2670(23)01095-4
doi: 10.1016/j.aca.2023.341874
pii:
doi:
Substances chimiques
Carbon
7440-44-0
Water
059QF0KO0R
Fluorescent Dyes
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
341874Informations de copyright
Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: The authors declare no conflict of interest.Jose M Costa-Fernandez reports financial support was provided by Gobierno del Principado de Asturias Consejería de Ciencia, Innovación y Universidad. Guillermo Redondo-Fernandez reports financial support was provided by Government of Principality of Asturias. Jorge Ruiz Encinar reports financial support was provided by Spain Ministry of Science and Innovation. Ana Soldado reports financial support was provided by Spain Ministry of Science and Innovation.