Methylene C(sp

Cross-Coupling C−H Activation Natural Products Total Synthesis

Journal

Angewandte Chemie (International ed. in English)
ISSN: 1521-3773
Titre abrégé: Angew Chem Int Ed Engl
Pays: Germany
ID NLM: 0370543

Informations de publication

Date de publication:
23 Nov 2023
Historique:
received: 24 10 2023
pubmed: 24 11 2023
medline: 24 11 2023
entrez: 24 11 2023
Statut: aheadofprint

Résumé

The divergent synthesis of two indane polyketides of the indidene family, namely (±)-indidene A (11 steps, 1.7 %) and (+)-indidene C (13 steps, 1.3 %), is reported. The synthesis of the trans-configured common indane intermediate was enabled by palladium(0)-catalyzed methylene C(sp

Identifiants

pubmed: 37997293
doi: 10.1002/anie.202316103
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e202316103

Subventions

Organisme : Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
ID : 200021_184608
Organisme : Universität Basel

Informations de copyright

© 2023 Wiley-VCH GmbH.

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Auteurs

Anton Kudashev (A)

University of Basel, Department of Chemistry, St. Johanns-Ring 19, 4056, Basel, Switzerland.

Stefania Vergura (S)

University of Basel, Department of Chemistry, St. Johanns-Ring 19, 4056, Basel, Switzerland.

Marco Zuccarello (M)

University of Basel, Department of Chemistry, St. Johanns-Ring 19, 4056, Basel, Switzerland.

Thomas Bürgi (T)

University of Geneva, Department of Physical Chemistry, 30 Quai Ernest-Ansermet, 1211, Geneva 4, Switzerland.

Olivier Baudoin (O)

University of Basel, Department of Chemistry, St. Johanns-Ring 19, 4056, Basel, Switzerland.

Classifications MeSH