Development of a Screening Method for Fluoroquinolones in Meat Samples Using Molecularly Imprinted Carbon Dots.

carbon dots fluorescence quenching fluoroquinolones meat samples molecularly imprinted polymers nano-composites

Journal

Biosensors
ISSN: 2079-6374
Titre abrégé: Biosensors (Basel)
Pays: Switzerland
ID NLM: 101609191

Informations de publication

Date de publication:
07 Nov 2023
Historique:
received: 10 10 2023
revised: 27 10 2023
accepted: 02 11 2023
medline: 27 11 2023
pubmed: 24 11 2023
entrez: 24 11 2023
Statut: epublish

Résumé

An accurate and simple screening method has been developed for the determination of fluoroquinolone antibiotics. Carbon dots were synthesized by simple hydrothermal treatment as highly fluorescent nano-sensors. They were subsequently used in the synthesis of organic-based molecularly imprinted polymers to develop fluorescence-based polymeric composites using enoxacin as a representative dummy template molecule of fluoroquinolones. The method was optimized concerning the pH of the medium and composite concentration. The normalized fluorescence intensity showed efficient quenching under optimized conditions upon successive addition of the template, with an excellent correlation coefficient. The proposed method was applied to eight other fluoroquinolones, exhibiting, in all cases, good correlation coefficients (0.65-0.992) within the same linearity range (0.03-2.60 mg mL

Identifiants

pubmed: 37998147
pii: bios13110972
doi: 10.3390/bios13110972
pmc: PMC10669409
pii:
doi:

Substances chimiques

Fluoroquinolones 0
Enrofloxacin 3DX3XEK1BN
Carbon 7440-44-0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : A. N. Research funded by MINECO
ID : (PID2021-127457OB-C21/C22)

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Auteurs

Ahmed Faried Abdel Hakiem (AFA)

Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, South Valley University, Qena 83523, Egypt.
Department of Analytical Chemistry, Faculty of Chemistry, Universidad Complutense de Madrid, 28040 Madrid, Spain.

Idoia Urriza-Arsuaga (I)

Independent Researcher, 28007 Madrid, Spain.

Javier L Urraca (JL)

Department of Analytical Chemistry, Faculty of Chemistry, Universidad Complutense de Madrid, 28040 Madrid, Spain.

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Classifications MeSH