Surgical Treatment for Early Cervical Cancer in the HPV Era: State of the Art.

HPV cervical dysplasia early cervical cancer surgical treatment

Journal

Healthcare (Basel, Switzerland)
ISSN: 2227-9032
Titre abrégé: Healthcare (Basel)
Pays: Switzerland
ID NLM: 101666525

Informations de publication

Date de publication:
10 Nov 2023
Historique:
received: 07 08 2023
revised: 12 10 2023
accepted: 08 11 2023
medline: 24 11 2023
pubmed: 24 11 2023
entrez: 24 11 2023
Statut: epublish

Résumé

Cervical cancer (CC) is the fourth most common cancer among women worldwide. The aim of this study is to focus on the state of the art of CC prevention, early diagnosis, and treatment and, within the latter, the role of surgery in the various stages of the disease with a focus on the impact of the LACC study (Laparoscopic Approach to Cervical Cancer trial) on the scientific debate and clinical practice. We have discussed the controversial application of minimally invasive surgery (MIS) for tumors < 2 cm and the possibility of fertility-sparing surgery on young women desirous of pregnancy. This analysis provides support for surgeons in the choice of better management, including patients with a desire for offspring and the need for sentinel node biopsy (SNB) rather than pelvic lymphadenectomy for tumors < 4 cm, and without suspicious lymph nodes' involvement on imaging. Vaccines and early diagnosis of pre-cancerous lesions are the most effective public health tool to tackle cervical cancer worldwide.

Identifiants

pubmed: 37998434
pii: healthcare11222942
doi: 10.3390/healthcare11222942
pmc: PMC10671714
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

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Auteurs

Mario Palumbo (M)

Department of Public Health, School of Medicine, University of Naples "Federico II", 80131 Naples, Italy.

Luigi Della Corte (L)

Department of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples "Federico II", 80131 Naples, Italy.

Carlo Ronsini (C)

Department of Woman, Child and General and Specialized Surgery, School of Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.

Serena Guerra (S)

Department of Public Health, School of Medicine, University of Naples "Federico II", 80131 Naples, Italy.

Pierluigi Giampaolino (P)

Department of Public Health, School of Medicine, University of Naples "Federico II", 80131 Naples, Italy.

Giuseppe Bifulco (G)

Department of Public Health, School of Medicine, University of Naples "Federico II", 80131 Naples, Italy.

Classifications MeSH