Diagnosis of Chronic Pulmonary Aspergillosis: Clinical, Radiological or Laboratory?

antibody chronic pulmonary aspergillosis clinical symptoms laboratory diagnosis radiological findings

Journal

Journal of fungi (Basel, Switzerland)
ISSN: 2309-608X
Titre abrégé: J Fungi (Basel)
Pays: Switzerland
ID NLM: 101671827

Informations de publication

Date de publication:
06 Nov 2023
Historique:
received: 11 10 2023
revised: 27 10 2023
accepted: 03 11 2023
medline: 24 11 2023
pubmed: 24 11 2023
entrez: 24 11 2023
Statut: epublish

Résumé

Chronic pulmonary aspergillosis (CPA) is a chronic progressive lung disease associated with a poor prognosis and a 5-year mortality rate of approximately 40-50%. The disease is characterized by slowly progressive destruction of the lung parenchyma, in the form of multiple cavities, nodules, infiltrates or fibrosis. CPA can be challenging to diagnose due to its non-specific symptoms and similarities with other respiratory conditions combined with the poor awareness of the medical community about the disease. This can result in delayed treatment even for years and worsening of the patient's condition. Serological tests certainly play a significant role in diagnosing CPA but cannot be interpreted without radiological confirmation of CPA. Although many data are published on this hot topic, there is yet no single definitive test for diagnosing CPA, and a multidisciplinary approach which involves a combination of clinical picture, radiological findings, microbiological results and exclusion of other mimicking diseases, is essential for the accurate diagnosis of CPA.

Identifiants

pubmed: 37998889
pii: jof9111084
doi: 10.3390/jof9111084
pmc: PMC10672318
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Références

Med Mycol. 2019 Apr 1;57(Supplement_2):S104-S109
pubmed: 30816975
BMC Pulm Med. 2020 Apr 15;20(1):89
pubmed: 32293386
Virulence. 2023 Dec;14(1):2172264
pubmed: 36752587
J Clin Microbiol. 2019 Feb 27;57(3):
pubmed: 30626661
BMC Pulm Med. 2016 Aug 18;16(1):123
pubmed: 27538521
PLoS One. 2020 Mar 17;15(3):e0222738
pubmed: 32182249
J Fungi (Basel). 2021 Oct 07;7(10):
pubmed: 34682263
Infect Drug Resist. 2023 Apr 14;16:2217-2226
pubmed: 37081946
Intern Med. 2023 Nov 15;62(22):3291-3298
pubmed: 36927976
Medicine (Baltimore). 2019 Apr;98(16):e15021
pubmed: 31008929
Front Microbiol. 2018 Apr 09;9:691
pubmed: 29686661
Clin Microbiol Infect. 2019 Sep;25(9):1157.e1-1157.e7
pubmed: 30685498
Int J Tuberc Lung Dis. 2021 Jul 1;25(7):537-546
pubmed: 34183098
Intern Med. 2017;56(4):449-453
pubmed: 28202870
PLoS Pathog. 2020 Jul 15;16(7):e1008645
pubmed: 32667960
Thorac Cancer. 2023 May;14(15):1408-1410
pubmed: 37035863
Med Mycol. 2021 Apr 6;59(4):327-334
pubmed: 32642756
Eukaryot Cell. 2007 Aug;6(8):1380-91
pubmed: 17557878
Int J Tuberc Lung Dis. 2021 Jul 1;25(7):519-520
pubmed: 34183095
Pol J Microbiol. 2021 Mar;70(1):3-11
pubmed: 33815522
Respir Med. 2018 Aug;141:121-131
pubmed: 30053957
Appl Environ Microbiol. 2019 Mar 6;85(6):
pubmed: 30635379
Lancet Infect Dis. 2017 Nov;17(11):e357-e366
pubmed: 28774699
Diagn Interv Imaging. 2015 May;96(5):435-42
pubmed: 25753544
Lancet Infect Dis. 2016 Nov;16(11):e251-e260
pubmed: 27638360
Radiol Bras. 2015 Nov-Dec;48(6):400-1
pubmed: 26811560
Med Mycol. 2005 May;43 Suppl 1:S147-54
pubmed: 16110807
Front Med (Lausanne). 2022 Feb 11;9:811807
pubmed: 35223906
Clin Respir J. 2020 Jun;14(6):571-577
pubmed: 32077238
Med Mycol. 2005 May;43 Suppl 1:S207-38
pubmed: 16110814
J Fungi (Basel). 2020 Jun 02;6(2):
pubmed: 32498415
Medicine (Baltimore). 2017 Oct;96(42):e8315
pubmed: 29049239
Med Mycol. 2013 Nov;51(8):811-7
pubmed: 23834282
J Immunol. 2014 Jun 1;192(11):5332-42
pubmed: 24790151
PLoS One. 2021 Nov 12;16(11):e0259766
pubmed: 34767589
Eur Respir Rev. 2022 Nov 29;31(166):
pubmed: 36450372
Emerg Infect Dis. 2018 Aug;24(8):
pubmed: 30016256
Front Microbiol. 2018 Aug 17;9:1810
pubmed: 30174658
Respiration. 2018;96(2):159-170
pubmed: 29982245
J Fungi (Basel). 2020 Mar 26;6(2):
pubmed: 32225054
Clin Microbiol Rev. 2019 Nov 13;33(1):
pubmed: 31722890
Clin Respir J. 2018 Nov;12(11):2566-2572
pubmed: 30191673
J Fungi (Basel). 2020 May 20;6(2):
pubmed: 32443672
Med Mycol. 2012 Nov;50(8):811-7
pubmed: 22568603
J Mycol Med. 2020 Dec;30(4):101041
pubmed: 32950379
Cell Microbiol. 2007 Oct;9(10):2315-22
pubmed: 17587328
Respir Med. 2013 Jul;107(7):1094-100
pubmed: 23632100
Am J Trop Med Hyg. 2022 Nov 30;108(1):22-26
pubmed: 36450228
Eur J Clin Microbiol Infect Dis. 2020 Jan;39(1):1-3
pubmed: 31811506
Diagn Pathol. 2015 Sep 03;10:153
pubmed: 26334307
Ann Allergy Asthma Immunol. 2017 Sep;119(3):253-257
pubmed: 28801088
Respiration. 2014;88(2):162-74
pubmed: 24943102
Microbiol Spectr. 2023 Jun 15;11(3):e0026423
pubmed: 37125929
J Fungi (Basel). 2022 Mar 13;8(3):
pubmed: 35330299
J Clin Microbiol. 2017 Jun;55(6):1738-1746
pubmed: 28330887
Respir Med. 2012 May;106(5):724-9
pubmed: 22349065
Antimicrob Agents Chemother. 2018 Jun 26;62(7):
pubmed: 29760132
J Fungi (Basel). 2016 Jun 07;2(2):
pubmed: 29376935
Eur Respir J. 2011 Apr;37(4):865-72
pubmed: 20595150
Mycopathologia. 2023 Oct;188(5):603-621
pubmed: 37289362
Heliyon. 2023 Apr 07;9(4):e15356
pubmed: 37123983
BMC Microbiol. 2010 Apr 08;10:105
pubmed: 20377900
Clin Microbiol Infect. 2021 Sep;27(9):1230-1241
pubmed: 33601011
J Fungi (Basel). 2021 Jun 12;7(6):
pubmed: 34204844
Eur Respir J. 2016 Jan;47(1):45-68
pubmed: 26699723

Auteurs

Aleksandra Barac (A)

Clinic for Infectious and Tropical Diseases, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.

Ankica Vujovic (A)

Clinic for Infectious and Tropical Diseases, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.

Ana Drazic (A)

Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.

Goran Stevanovic (G)

Clinic for Infectious and Tropical Diseases, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.

Bianca Paglietti (B)

Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.

Katarina Lukic (K)

Center for Radiology and MRI, University Clinical Center of Serbia, 11000 Belgrade, Serbia.

Maja Stojanovic (M)

Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Clinic of Allergy and Immunology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.

Mihailo Stjepanovic (M)

Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Clinic for Pulmonology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.

Classifications MeSH