Efficacy of an Internet-Delivered Intervention for Improving Insomnia Severity and Functioning in Veterans: Randomized Controlled Trial.

RCT RCTs cognitive behavioral therapy insomnia internet intervention online intervention randomized controlled trial sleep treatment veteran veterans veterans’ health

Journal

JMIR mental health
ISSN: 2368-7959
Titre abrégé: JMIR Ment Health
Pays: Canada
ID NLM: 101658926

Informations de publication

Date de publication:
24 Nov 2023
Historique:
received: 03 07 2023
accepted: 06 10 2023
revised: 26 09 2023
medline: 24 11 2023
pubmed: 24 11 2023
entrez: 24 11 2023
Statut: epublish

Résumé

Despite a growing evidence base that internet-delivered cognitive behavioral therapy for insomnia (iCBT-I) is associated with decreased insomnia severity, its efficacy has been minimally examined in veterans. The objective of this study was to evaluate the efficacy of an unguided iCBT-I (Sleep Healthy Using the Internet [SHUTi]) among veterans. We conducted a single-blind, randomized controlled trial in Operation Enduring Freedom, Operation Iraqi Freedom, and Operation New Dawn veterans eligible for Veterans Health Administration care. Participants were randomly assigned (1:1) to receive SHUTi (a self-guided and interactive program) or an Insomnia Education Website (IEW) that provided nontailored and fixed insomnia information. Web-based assessments were administered at baseline, postintervention, 6 months postintervention, and 1 year postintervention. The primary outcome was self-reported insomnia severity (Insomnia Severity Index [ISI]). Secondary outcomes were self-reported mental and physical health functioning (Veterans RAND 36-item Health Survey). Exploratory outcomes comprised sleep diary parameters. Of the 231 randomized participants (mean age 39.3, SD 7.8 years; 170/231, 73.5% male sex; 26/231, 11.3% Black; 172/231, 74.5% White; 10/231, 4.3% multiracial; and 17/231, 7.4% other; 36/231, 15.6% Hispanic) randomized between April 2018 and January 2019, a total of 116 (50.2%) were randomly assigned to SHUTi and 115 (49.8%) to the IEW. In intent-to-treat analyses, SHUTi participants experienced significantly larger ISI decreases compared with IEW participants at all time points (generalized η Self-administered iCBT-I was associated with immediate and long-term improvements in insomnia severity. Findings suggest that leveraging technology to meet insomnia treatment demands among veterans may be a promising approach. ClinicalTrials.gov NCT03366870; https://clinicaltrials.gov/ct2/show/NCT03366870.

Sections du résumé

BACKGROUND BACKGROUND
Despite a growing evidence base that internet-delivered cognitive behavioral therapy for insomnia (iCBT-I) is associated with decreased insomnia severity, its efficacy has been minimally examined in veterans.
OBJECTIVE OBJECTIVE
The objective of this study was to evaluate the efficacy of an unguided iCBT-I (Sleep Healthy Using the Internet [SHUTi]) among veterans.
METHODS METHODS
We conducted a single-blind, randomized controlled trial in Operation Enduring Freedom, Operation Iraqi Freedom, and Operation New Dawn veterans eligible for Veterans Health Administration care. Participants were randomly assigned (1:1) to receive SHUTi (a self-guided and interactive program) or an Insomnia Education Website (IEW) that provided nontailored and fixed insomnia information. Web-based assessments were administered at baseline, postintervention, 6 months postintervention, and 1 year postintervention. The primary outcome was self-reported insomnia severity (Insomnia Severity Index [ISI]). Secondary outcomes were self-reported mental and physical health functioning (Veterans RAND 36-item Health Survey). Exploratory outcomes comprised sleep diary parameters.
RESULTS RESULTS
Of the 231 randomized participants (mean age 39.3, SD 7.8 years; 170/231, 73.5% male sex; 26/231, 11.3% Black; 172/231, 74.5% White; 10/231, 4.3% multiracial; and 17/231, 7.4% other; 36/231, 15.6% Hispanic) randomized between April 2018 and January 2019, a total of 116 (50.2%) were randomly assigned to SHUTi and 115 (49.8%) to the IEW. In intent-to-treat analyses, SHUTi participants experienced significantly larger ISI decreases compared with IEW participants at all time points (generalized η
CONCLUSIONS CONCLUSIONS
Self-administered iCBT-I was associated with immediate and long-term improvements in insomnia severity. Findings suggest that leveraging technology to meet insomnia treatment demands among veterans may be a promising approach.
TRIAL REGISTRATION BACKGROUND
ClinicalTrials.gov NCT03366870; https://clinicaltrials.gov/ct2/show/NCT03366870.

Identifiants

pubmed: 37999953
pii: v10i1e50516
doi: 10.2196/50516
pmc: PMC10709797
doi:

Banques de données

ClinicalTrials.gov
['NCT03366870']

Types de publication

Journal Article

Langues

eng

Pagination

e50516

Informations de copyright

©Sarra Nazem, Sean M Barnes, Jeri E Forster, Trisha A Hostetter, Lindsey L Monteith, Emily B Kramer, Laurel A Gaeddert, Lisa A Brenner. Originally published in JMIR Mental Health (https://mental.jmir.org), 24.11.2023.

Références

Health Informatics J. 2018 Mar;24(1):3-13
pubmed: 27354394
Am J Phys Med Rehabil. 2010 Jun;89(6):437-45
pubmed: 20489391
J Rehabil Res Dev. 2012;49(6):867-78
pubmed: 23299258
Psychother Psychosom. 2012;81(4):206-16
pubmed: 22585048
Ann Intern Med. 2020 Mar 3;172(5):325-336
pubmed: 32066145
J Clin Neurosci. 2021 Jul;89:430-436
pubmed: 34074598
Psychiatry Res. 2018 May;263:108-114
pubmed: 29524908
Arch Gen Psychiatry. 1961 Jun;4:561-71
pubmed: 13688369
Sleep Breath. 2016 Mar;20(1):379-82
pubmed: 25924933
NeuroRehabilitation. 2013;32(3):693-6
pubmed: 23648625
Psychol Assess. 2022 Feb;34(2):197-203
pubmed: 34941354
J Psychosom Res. 1967 Aug;11(2):213-8
pubmed: 6059863
Clin Psychol Rev. 2009 Dec;29(8):674-84
pubmed: 19744760
Med Care. 1996 Mar;34(3):220-33
pubmed: 8628042
Int Rev Psychiatry. 2014 Apr;26(2):205-13
pubmed: 24892895
JMIR Form Res. 2021 Dec 9;5(12):e29573
pubmed: 34889746
Harv Rev Psychiatry. 2010 Mar-Apr;18(2):80-95
pubmed: 20235773
Sleep Med. 2021 Aug;84:283-288
pubmed: 34214960
Front Psychiatry. 2021 Dec 23;12:798453
pubmed: 35002813
Am J Public Health. 2012 Mar;102 Suppl 1:S93-7
pubmed: 22390611
Sleep Med Rev. 2016 Dec;30:1-10
pubmed: 26615572
Sleep Med. 2020 Nov;75:315-325
pubmed: 32950013
Clin Psychol Rev. 2015 Aug;40:195-212
pubmed: 26164549
Sleep. 2018 Jun 1;41(6):
pubmed: 29618098
Sci Rep. 2023 Feb 2;13(1):1929
pubmed: 36732610
JAMA. 1989 Aug 18;262(7):925-30
pubmed: 2754793
Suicide Life Threat Behav. 2016 Feb;46(1):88-95
pubmed: 26052862
Curr Psychiatry Rep. 2013 Oct;15(10):401
pubmed: 24005883
Sleep. 2009 Dec;32(12):1549-58
pubmed: 20041590
Psychooncology. 2012 Jul;21(7):695-705
pubmed: 21538678
Syst Rev. 2014 Feb 25;3:18
pubmed: 24568642
E J Appl Psychol. 2008;4(2):32-42
pubmed: 20953264
Implement Res Pract. 2021 Nov 15;2:26334895211053659
pubmed: 37090002
Sleep. 2006 Nov;29(11):1398-414
pubmed: 17162986
Am J Psychiatry. 2002 Jan;159(1):5-11
pubmed: 11772681
Sleep. 2011 May 01;34(5):601-8
pubmed: 21532953
Arch Gen Psychiatry. 2009 Jul;66(7):692-8
pubmed: 19581560
J Consult Clin Psychol. 1988 Dec;56(6):893-7
pubmed: 3204199
J Clin Sleep Med. 2021 Jun 1;17(6):1267-1277
pubmed: 33656983
Interact J Med Res. 2019 Jul 24;8(3):e12408
pubmed: 31342904
Behav Res Ther. 2014 Oct;61:78-88
pubmed: 25194223
J Psychiatr Res. 2003 Jan-Feb;37(1):9-15
pubmed: 12482465
Sleep Med. 2020 Feb;66:174-183
pubmed: 31901759
Am J Med Qual. 1999 Jan-Feb;14(1):28-38
pubmed: 10446661
Curr Sleep Med Rep. 2017;3(2):48-56
pubmed: 28553574
Sleep. 2009 Jun;32(6):807-15
pubmed: 19544758
Contemp Clin Trials. 2019 Apr;79:73-79
pubmed: 30825525
Behav Sleep Med. 2011;9(4):216-23
pubmed: 22003975
J Clin Sleep Med. 2012 Apr 15;8(2):209-18
pubmed: 22505869
Lancet Psychiatry. 2016 Apr;3(4):333-41
pubmed: 26827250
J Med Internet Res. 2019 Jan 25;21(1):e11752
pubmed: 30681966
Sleep. 2007 Feb;30(2):213-8
pubmed: 17326547
Mil Med. 2014 May;179(5):521-8
pubmed: 24806497
Lancet Digit Health. 2020 Aug;2(8):e397-e406
pubmed: 33328044
Behav Sleep Med. 2019 Mar-Apr;17(2):137-155
pubmed: 28345961
Psychol Assess. 2015 Jun;27(2):501-512
pubmed: 25496086
Sleep. 2016 Jul 01;39(7):1399-410
pubmed: 27091538
Sleep. 2001 Jun 15;24(4):411-7
pubmed: 11403525
Sleep. 2017 Jun 1;40(6):
pubmed: 28472528
NIH Consens State Sci Statements. 2005 Jun 13-15;22(2):1-30
pubmed: 17308547
Clin Psychol Rev. 2005 Jul;25(5):539-58
pubmed: 15951083
Int J Chronobiol. 1976;4(2):97-110
pubmed: 1027738
Curr Psychiatry Rep. 2019 Jun 4;21(7):50
pubmed: 31161406
Sleep Med. 2001 Jul;2(4):297-307
pubmed: 11438246
Behav Ther. 2022 May;53(3):440-457
pubmed: 35473648
JAMA Psychiatry. 2022 Jun 1;79(6):538-549
pubmed: 35442432
Sleep. 2012 Feb 01;35(2):287-302
pubmed: 22294820
Psychol Res Behav Manag. 2011;4:21-8
pubmed: 22114532
Front Psychol. 2013 Nov 26;4:863
pubmed: 24324449
Am J Psychiatry. 1994 Aug;151(8):1172-80
pubmed: 8037252
Sleep Med Rev. 2021 Apr;56:101404
pubmed: 33370637
J Pers Assess. 1991 Apr;56(2):289-307
pubmed: 2056423
J Clin Psychol. 2013 Oct;69(10):1078-93
pubmed: 24014057
JAMA Psychiatry. 2017 Jan 01;74(1):68-75
pubmed: 27902836
J Ambul Care Manage. 2004 Jul-Sep;27(3):263-80
pubmed: 15287216
J Abnorm Psychol. 2017 Aug;126(6):739-749
pubmed: 28557509
J Consult Clin Psychol. 1995 Feb;63(1):79-89
pubmed: 7896994
J Clin Sleep Med. 2015 Sep 15;11(9):995-1005
pubmed: 26094928
Psychiatr Serv. 2016 Feb;67(2):176-83
pubmed: 26620286
Eval Program Plann. 1983;6(3-4):299-313
pubmed: 10267258
Behav Res Ther. 2014 Feb;53:41-6
pubmed: 24412462
Sleep. 1999 Dec 15;22(8):1134-56
pubmed: 10617176
Clin Psychol Rev. 2017 Jun;54:1-16
pubmed: 28371648

Auteurs

Sarra Nazem (S)

Dissemination & Training Division, National Center for Posttraumatic Stress Disorder, Menlo Park, CA, United States.
Veterans Affairs Rocky Mountain Mental Illness Research, Education and Clinical Center, Aurora, CO, United States.

Sean M Barnes (SM)

Veterans Affairs Rocky Mountain Mental Illness Research, Education and Clinical Center, Aurora, CO, United States.
Department of Psychiatry, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.

Jeri E Forster (JE)

Veterans Affairs Rocky Mountain Mental Illness Research, Education and Clinical Center, Aurora, CO, United States.
Department of Physical Medicine and Rehabilitation, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.

Trisha A Hostetter (TA)

Veterans Affairs Rocky Mountain Mental Illness Research, Education and Clinical Center, Aurora, CO, United States.

Lindsey L Monteith (LL)

Veterans Affairs Rocky Mountain Mental Illness Research, Education and Clinical Center, Aurora, CO, United States.
Department of Psychiatry, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Department of Physical Medicine and Rehabilitation, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.

Emily B Kramer (EB)

Veterans Affairs Rocky Mountain Mental Illness Research, Education and Clinical Center, Aurora, CO, United States.

Laurel A Gaeddert (LA)

Veterans Affairs Rocky Mountain Mental Illness Research, Education and Clinical Center, Aurora, CO, United States.

Lisa A Brenner (LA)

Veterans Affairs Rocky Mountain Mental Illness Research, Education and Clinical Center, Aurora, CO, United States.
Department of Psychiatry, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Department of Physical Medicine and Rehabilitation, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Department of Neurology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.

Classifications MeSH