Toluidine blue O photosensitizer combined with caffeic acid improves antibacterial performance by increasing the permeability of cell membrane.
Antibacterial photodynamic therapy
Caffeic acid
Membrane permeability
Toluidine blue O
Journal
Colloids and surfaces. B, Biointerfaces
ISSN: 1873-4367
Titre abrégé: Colloids Surf B Biointerfaces
Pays: Netherlands
ID NLM: 9315133
Informations de publication
Date de publication:
Jan 2024
Jan 2024
Historique:
received:
11
08
2023
revised:
25
10
2023
accepted:
16
11
2023
medline:
7
12
2023
pubmed:
25
11
2023
entrez:
24
11
2023
Statut:
ppublish
Résumé
Photodynamic therapy has always been an antibacterial tool for solving multi-drug resistant bacteria problem, but the side effects and the low efficiency due to the high aggregation and low solubility of photosensitizers limit its application. Due to the anti-inflammatory effect of caffeic acid, two novel photosensitizers (CA-1-TBO, CA-TBO) were synthesized by conjugating caffeic acid with toluidine blue O (TBO). The structures have been characterized by
Identifiants
pubmed: 38000122
pii: S0927-7765(23)00542-8
doi: 10.1016/j.colsurfb.2023.113657
pii:
doi:
Substances chimiques
Photosensitizing Agents
0
Anti-Bacterial Agents
0
Tolonium Chloride
15XUH0X66N
caffeic acid
U2S3A33KVM
Octanols
0
Water
059QF0KO0R
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
113657Informations de copyright
Copyright © 2023 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.