Glutathionyl Hemoglobin and Its Emerging Role as a Clinical Biomarker of Chronic Oxidative Stress.
S-glutathionylation
clinical marker
glutathione
glutathionyl hemoglobin
glutathionylated hemoglobin
oxidative stress
post-translational modification
Journal
Antioxidants (Basel, Switzerland)
ISSN: 2076-3921
Titre abrégé: Antioxidants (Basel)
Pays: Switzerland
ID NLM: 101668981
Informations de publication
Date de publication:
07 Nov 2023
07 Nov 2023
Historique:
received:
19
10
2023
revised:
02
11
2023
accepted:
04
11
2023
medline:
25
11
2023
pubmed:
25
11
2023
entrez:
25
11
2023
Statut:
epublish
Résumé
Hemoglobin is one of the proteins that are more susceptible to S-glutathionylation and the levels of its modified form, glutathionyl hemoglobin (HbSSG), increase in several human pathological conditions. The scope of the present review is to provide knowledge about how hemoglobin is subjected to S-glutathionylation and how this modification affects its functionality. The different diseases that showed increased levels of HbSSG and the methods used for its quantification in clinical investigations will be also outlined. Since there is a growing need for precise and reliable methods for markers of oxidative stress in human blood, this review highlights how HbSSG is emerging more and more as a good indicator of severe oxidative stress but also as a key pathogenic factor in several diseases.
Identifiants
pubmed: 38001829
pii: antiox12111976
doi: 10.3390/antiox12111976
pmc: PMC10669486
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
Eur J Biochem. 1982 Apr;123(3):513-9
pubmed: 7075597
Bioconjug Chem. 2011 Apr 20;22(4):785-93
pubmed: 21384878
Indian J Psychiatry. 2012 Jul;54(3):244-7
pubmed: 23226848
Clin Chem. 2003 Feb;49(2):327-30
pubmed: 12560364
Chem Biol Interact. 2018 Feb 1;281:121-136
pubmed: 29258867
Amino Acids. 2022 Apr;54(4):675-686
pubmed: 34129091
Antioxid Redox Signal. 2016 Jul 20;25(3):119-46
pubmed: 26906267
Kidney Int Suppl. 2001 Feb;78:S155-8
pubmed: 11169002
J Struct Biol. 2019 Dec 1;208(3):107386
pubmed: 31518635
Eur J Clin Invest. 2001 Nov;31(11):1007-11
pubmed: 11737244
Int J Mol Sci. 2020 Oct 30;21(21):
pubmed: 33143095
J Cancer Res Ther. 2021 Jan-Mar;17(1):22-28
pubmed: 33723127
Chem Res Toxicol. 2014 May 19;27(5):864-72
pubmed: 24641270
Arch Biochem Biophys. 2004 Jan 1;421(1):108-14
pubmed: 14678791
J Pediatr. 2003 May;142(5):583-5
pubmed: 12756395
Expert Rev Clin Immunol. 2022 Sep;18(9):923-931
pubmed: 35904251
Free Radic Biol Med. 2004 Feb 15;36(4):464-70
pubmed: 14975449
J Chromatogr B Biomed Sci Appl. 2000 Sep 1;746(1):91-4
pubmed: 11048744
Anal Biochem. 2003 Jan 15;312(2):85-90
pubmed: 12531191
Ann Emerg Med. 1982 Apr;11(4):214-21
pubmed: 7073040
Antioxid Redox Signal. 2013 May 1;18(13):1623-41
pubmed: 23075118
J Heart Valve Dis. 1998 Jul;7(4):387-95
pubmed: 9697059
Molecules. 2019 Apr 22;24(8):
pubmed: 31013638
Neurol Res. 2017 Jan;39(1):73-82
pubmed: 27809706
Antioxid Redox Signal. 2012 Mar 15;16(6):543-66
pubmed: 22066468
Antioxid Redox Signal. 2020 Apr 1;32(10):677-700
pubmed: 31813265
Clin Chem. 2000 Jan;46(1):82-8
pubmed: 10620575
Clin Chem. 1995 Mar;41(3):448-54
pubmed: 7882521
J Neurosci Res. 2007 May 15;85(7):1506-14
pubmed: 17387692
Int J Cell Biol. 2013;2013:797914
pubmed: 24348565
Antioxid Redox Signal. 2005 Mar-Apr;7(3-4):348-66
pubmed: 15706083
Bioconjug Chem. 2012 Dec 19;23(12):2344-53
pubmed: 23153198
South Med J. 2011 Nov;104(11):757-61
pubmed: 22024786
Indian J Med Res. 2019 Apr;149(4):497-502
pubmed: 31411173
Anal Biochem. 2005 Jan 15;336(2):279-88
pubmed: 15620893
Arch Neurol. 1999 Oct;56(10):1201-8
pubmed: 10520935
Front Cell Dev Biol. 2014 Nov 17;2:68
pubmed: 25453035
Redox Biol. 2020 Sep;36:101679
pubmed: 32818797
Oxid Med Cell Longev. 2017;2017:2818565
pubmed: 29456785
Molecules. 2023 Jan 04;28(2):
pubmed: 36677554
Eur J Prev Cardiol. 2020 Mar;27(4):394-406
pubmed: 31408370
J Clin Lab Anal. 2009;23(5):319-23
pubmed: 19774625
Nat Rev Cardiol. 2021 Apr;18(4):251-275
pubmed: 33037326
Proc Natl Acad Sci U S A. 2004 Mar 16;101(11):3780-5
pubmed: 15004285
Biochim Biophys Acta. 1995 Feb 23;1243(2):230-8
pubmed: 7873567
J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Aug;855(1):59-65
pubmed: 17222592
Biochem J. 2016 Dec 15;473(24):4527-4550
pubmed: 27941030
Environ Health Perspect. 1997 Jun;105 Suppl 4:875-82
pubmed: 9255574
Cancer Cell. 2020 Aug 10;38(2):167-197
pubmed: 32649885
Biochem J. 1990 Jul 1;269(1):1-11
pubmed: 2198020
Int J Mol Sci. 2022 Dec 12;23(24):
pubmed: 36555387
Free Radic Biol Med. 1994 Mar;16(3):383-91
pubmed: 8063201
Ann Med. 2018 Mar;50(2):121-127
pubmed: 29237304
Molecules. 2021 Apr 26;26(9):
pubmed: 33926119
J Biol Chem. 1986 Nov 5;261(31):14710-6
pubmed: 3771548
Free Radic Biol Med. 1998 Dec;25(9):1044-8
pubmed: 9870557
Methods Enzymol. 2010;473:179-97
pubmed: 20513478
Am J Hematol. 1993 Jan;42(1):7-12
pubmed: 8416301
Clin Biochem. 2005 Oct;38(10):892-9
pubmed: 16051210
Arch Biochem Biophys. 2003 Sep 15;417(2):244-50
pubmed: 12941307
J Mol Cell Cardiol. 2012 Mar;52(3):559-67
pubmed: 21784079
Acta Haematol. 2012;127(1):26-30
pubmed: 21996674
J Chromatogr B Biomed Sci Appl. 1999 Aug 6;731(1):121-4
pubmed: 10491997
Int J Mol Sci. 2023 Aug 31;24(17):
pubmed: 37686361
Oxid Med Cell Longev. 2017;2017:8416763
pubmed: 28819546
J Cell Mol Med. 2004 Apr-Jun;8(2):201-12
pubmed: 15256068
Biochem J. 1980 Jul 15;190(1):125-30
pubmed: 7447929
Clin Chem. 2000 Feb;46(2):145-6
pubmed: 10657367
Anal Biochem. 1983 Jun;131(2):504-9
pubmed: 6614484
J Biol Chem. 2003 Apr 25;278(17):14607-13
pubmed: 12556467
MethodsX. 2019 Sep 10;6:1992-1998
pubmed: 31667096
Antioxid Redox Signal. 2006 Sep-Oct;8(9-10):1723-8
pubmed: 16987024
Ann Emerg Med. 1999 Nov;34(5):646-56
pubmed: 10533013
Mol Med. 2001 Sep;7(9):619-23
pubmed: 11778651
Antioxid Redox Signal. 2005 Jul-Aug;7(7-8):930-9
pubmed: 15998248
Hemoglobin. 2017 Jul - Nov;41(4-6):300-305
pubmed: 29210301
Biochem Soc Trans. 2004 Nov;32(Pt 5):655-8
pubmed: 15493980
Adv Exp Med Biol. 2017;960:443-467
pubmed: 28585211
Trends Biochem Sci. 2009 Feb;34(2):85-96
pubmed: 19135374
Antioxid Redox Signal. 2008 Nov;10(11):1941-88
pubmed: 18774901
Front Mol Biosci. 2020 Nov 09;7:569293
pubmed: 33263002
Curr Atheroscler Rep. 2017 Sep 18;19(11):42
pubmed: 28921056
World Allergy Organ J. 2012 Jan;5(1):9-19
pubmed: 23268465
Clin Biochem. 2007 Sep;40(13-14):986-94
pubmed: 17574228