COVID-19
GPX3
antioxidant genetic profile
disease progression
inflammatory markers
oxidative stress
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
10 Nov 2023
10 Nov 2023
Historique:
received:
29
09
2023
revised:
17
10
2023
accepted:
21
10
2023
medline:
27
11
2023
pubmed:
25
11
2023
entrez:
25
11
2023
Statut:
epublish
Résumé
In SARS-CoV-2 infection, excessive activation of the immune system intensively increases reactive oxygen species levels, causing harmful hyperinflammatory and oxidative state cumulative effects which may contribute to COVID-19 severity. Therefore, we assumed that antioxidant genetic profile, independently and complemented with laboratory markers, modulates COVID-19 severity. The study included 265 COVID-19 patients. Polymorphism of G
Identifiants
pubmed: 38003341
pii: ijms242216151
doi: 10.3390/ijms242216151
pmc: PMC10671662
pii:
doi:
Substances chimiques
Fibrinogen
9001-32-5
GPX3 protein, human
EC 1.11.1.-
Glutathione Peroxidase
EC 1.11.1.9
GSTO1 protein, human
EC 2.5.1.18
Glutathione Transferase
EC 2.5.1.18
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Science Fund of the Republic of Serbia
ID : Antioxidentification No7546803
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