Exploring the Association between Delirium and Malnutrition in COVID-19 Survivors: A Geriatric Perspective.


Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
09 Nov 2023
Historique:
received: 25 09 2023
revised: 06 11 2023
accepted: 07 11 2023
medline: 27 11 2023
pubmed: 25 11 2023
entrez: 25 11 2023
Statut: epublish

Résumé

Older individuals face an elevated risk of developing geriatric syndromes when confronted with acute stressors like COVID-19. We assessed the connection between in-hospital delirium, malnutrition, and frailty in a cohort of COVID-19 survivors. Patients aged ≥65, hospitalized in a tertiary hospital in Milan for SARS-CoV-2 pneumonia, were enrolled and screened for in-hospital delirium with the 4 'A's Test (4AT) performed twice daily (morning and evening) during hospital stay. Malnutrition was assessed with the malnutrition universal screening tool (MUST) at hospital admission and with the mini-nutritional assessment short-form (MNA-SF) one month after hospital discharge. Frailty was computed with the frailty index one month after hospital discharge. Fifty patients (median age 78.5, 56% male) were enrolled. At hospital admission, 10% were malnourished. The 13 patients (26%) who developed delirium were frailer (7 vs. 4), experienced a higher in-hospital mortality (5 vs. 3), and were more malnourished one month after discharge (3 of the 4 patients with delirium vs. 6 of the 28 patients without delirium who presented at follow up). The 4AT scores correlated with the MNA-SF scores (r = -0.55,

Identifiants

pubmed: 38004121
pii: nu15224727
doi: 10.3390/nu15224727
pmc: PMC10674410
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Ministero della Salute
ID : COVID-2020-12371617

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Auteurs

Sarah Damanti (S)

Vita Salute University, 20100 Milan, Italy.
General Medicine and Continuity of Care Unit, IRCCS San Raffaele Hospital, 20132 Milan, Italy.

Marta Cilla (M)

Center for Liver Disease, Division of Internal Medicine and Hepatology, IRCCS Ospedale San Raffaele, 20132 Milan, Italy.

Giordano Vitali (G)

General Medicine and Continuity of Care Unit, IRCCS San Raffaele Hospital, 20132 Milan, Italy.

Valeria Tiraferri (V)

Vita Salute University, 20100 Milan, Italy.

Chiara Pomaranzi (C)

Vita Salute University, 20100 Milan, Italy.

Giulia De Rubertis (G)

Vita Salute University, 20100 Milan, Italy.

Rebecca De Lorenzo (R)

Vita Salute University, 20100 Milan, Italy.

Giuseppe Di Lucca (G)

Unit of General Medicine and Advanced Care, IRCCS Ospedale San Raffaele, 20132 Milan, Italy.

Raffaella Scotti (R)

Unit of General Medicine and Advanced Care, IRCCS Ospedale San Raffaele, 20132 Milan, Italy.

Emanuela Messina (E)

Infectious Diseases Unit, San Raffaele Scientific Institute, 20132 Milan, Italy.

Raffaele Dell'Acqua (R)

Infectious Diseases Unit, San Raffaele Scientific Institute, 20132 Milan, Italy.

Monica Guffanti (M)

Infectious Diseases Unit, San Raffaele Scientific Institute, 20132 Milan, Italy.

Paola Cinque (P)

Infectious Diseases Unit, San Raffaele Scientific Institute, 20132 Milan, Italy.

Antonella Castagna (A)

Vita Salute University, 20100 Milan, Italy.
Infectious Diseases Unit, San Raffaele Scientific Institute, 20132 Milan, Italy.

Patrizia Rovere-Querini (P)

Vita Salute University, 20100 Milan, Italy.
General Medicine and Continuity of Care Unit, IRCCS San Raffaele Hospital, 20132 Milan, Italy.
Division of Immunology, Transplantation & Infectious Diseases, Università Vita-Salute San Raffaele, IRCCS Ospedale San Raffaele, 20132 Milan, Italy.

Moreno Tresoldi (M)

Unit of General Medicine and Advanced Care, IRCCS Ospedale San Raffaele, 20132 Milan, Italy.

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