Glial tone of aggression.

Aggression Astrocyte Cerebellum Fiber photometry Optogenetics Social interaction

Journal

Neuroscience research
ISSN: 1872-8111
Titre abrégé: Neurosci Res
Pays: Ireland
ID NLM: 8500749

Informations de publication

Date de publication:
24 Nov 2023
Historique:
received: 03 10 2023
revised: 16 11 2023
accepted: 20 11 2023
pubmed: 26 11 2023
medline: 26 11 2023
entrez: 25 11 2023
Statut: aheadofprint

Résumé

Anger transition is often abrupt. In this study, we investigated the mechanisms responsible for switching and modulating aggression levels. The cerebellum is considered a center for motor coordination and learning; however, its connection to social behavior has long been observed. Here, we used the resident-intruder paradigm in male mice and examined local field potential (LFP) changes, glial cytosolic ion fluctuations, and vascular dynamics in the cerebellar vermis throughout various phases of a combat sequence. Notably, we observed the emergence of theta band oscillations in the LFP and sustained elevations in glial Ca

Identifiants

pubmed: 38007191
pii: S0168-0102(23)00203-1
doi: 10.1016/j.neures.2023.11.008
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Conflict of interest The authors declare no conflicts of interest.

Auteurs

Yuki Asano (Y)

Super-network Brain Physiology, Graduate School of Life Sciences, Tohoku University, Sendai 980-8577 Japan.

Daichi Sasaki (D)

Super-network Brain Physiology, Graduate School of Life Sciences, Tohoku University, Sendai 980-8577 Japan.

Yoko Ikoma (Y)

Super-network Brain Physiology, Graduate School of Life Sciences, Tohoku University, Sendai 980-8577 Japan.

Ko Matsui (K)

Super-network Brain Physiology, Graduate School of Life Sciences, Tohoku University, Sendai 980-8577 Japan. Electronic address: matsui@med.tohoku.ac.jp.

Classifications MeSH